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All Journal Cermin Dunia Kedokteran Ophthalmologica Indonesiana
Amelia, Yufilia Suci
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Health Professions Medicine & Pharmacology Public Health

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Konjungtivitis pada COVID-19 Stefanie, Airina; Haryady, Stefanny; Amelia, Yufilia Suci
Cermin Dunia Kedokteran Vol 48, No 11 (2021): Kardio-SerebroVaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (110.315 KB) | DOI: 10.55175/cdk.v48i11.1550

Abstract

Corona Virus Disease 19 (COVID-19) pertama ditemukan di Wuhan, Cina, pada Desember 2019 dan telah menjadi ancaman kesehatan global. COVID-19 disebabkan oleh Severe Acute Respiratory Corona Virus 2 (SARS-CoV-2), ditransmisikan melalui droplet pernapasan atau kontak erat. Penelitian terbaru menyatakan bahwa konjungtiva dapat menjadi port d’entree SARS-CoV-2, dan menyebabkan gejala konjungtivitis. Jalur transmisi SARS-CoV 2 ke okuler diduga melalui inokulasi langsung dan melalui reseptor ACE2 yang diekspresikan di konjungtiva. Karakteristik konjungtivitis COVID-19 adalah sekret mukoid ataupun aqueous berlebih, sensasi tidak nyaman pada okuler seperti gatal, benda asing, atau rasa terbakar, serta hiperemis konjungtiva. Pada pemeriksaan RT PCR swab okuler ataupun nasofaring dapat positif pada 3 hingga 21 hari setelah onset gejala. Studi ini merupakan literature review. Artikel diambil dari database Google scholar, Pubmed, Lange, Elsevier, dengan kata kunci “ocular manifestation in COVID-19”, “characteristics of conjunctivitis in COVID-19”, “mechanism of COVID-19 in conjunctiva”. Artikel yang dipilih adalah jurnal yang dipublikasi sejak tanggal 1 Desember 2019 sampai 30 Oktober 2020. Corona Virus Disease 19 (COVID-19) was first discovered in Wuhan, China, in 2019 and has been declared as global health emergency. COVID-19 is caused by Severe Acute Respiratory Corona Virus 2 (SARS-CoV 2) transmitted through droplet and physical contact. Studies stated that conjunctiva is a potential port of entry of SARS-CoV2, which then leads to conjunctivitis. This literature review is based on analytic study on conjunctivitis in COVID-19. The transmission route is thought from direct inoculation and expression of ACE2 receptors from conjunctiva. Most common characteristics of conjunctivitis in COVID-19 are increased conjunctival secretions both mucoid and aqueous, and ocular discomfort such as itching, foreign bodies sensations, burning, and conjunctival hyperemia. RT PCR from both ocular and nasopharyngeal swabs were detectable from days 3 to 21 after the onset of symptoms. This study is a review on published articles from December 1st 2019 to October 30th 2020, in Google Scholar, PubMed, Lange, and Elsevier; selected with keywords “ocular manifestation in COVID-19”, “characteristics of conjunctivitis in COVID-19”, “mechanism of COVID-19 in conjunctiva”. 
THE ASSOCIATION BETWEEN ATRIAL FIBRILLATION AND CENTRAL RETINAL ARTERY OCCLUSION: A META-ANALYSIS AND SYSTEMATIC REVIEW: Oral Presentation - Observational Study - General practitioner Amelia, Yufilia Suci; Alberta, Ivana Beatrice; Angelia, Maria; Pratama, Kevin Gracia
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/qdf5xw44

Abstract

Introduction Central retinal artery occlusion (CRAO) is a condition where the central retinal artery is blocked. Atrial Fibrillation (AF) is commonly associated with retinal embolism that originates anywhere between the heart and the ophthalmic artery. This study aims to explore the incidence of AF in CRAO. Methods A systematic search was performed in three databases: Pubmed, EBSCO host, and Proquest. Newcastle-Ottawa Scale was used to assess the risk of bias in the study included. Results Our systematic review comprises six studies, 4 studies included CRAO patients as the study population and AF as the endpoint, and the other 2 studies with CRAO as the endpoint. Meta-analysis of the first group resulted in a significantly favorable AF incident after CRAO with an odds ratio (OR) of 1.46 (95% CI 1.17-1.81, p=0.0007). The second metaanalysis supports CRAO with an OR of 4.86 (95% CI 2.30-10.28, p<0.0001). Discussion Our study indicates that AF is a significant risk factor for CRAO. Extended cardiac monitoring may play a crucial diagnostic role in CRAO patients, and longer-term monitoring (23 years) may be a reasonable option as part of the diagnostic workup. Short-term monitoring alone may fail to detect a significant proportion of patients with underlying AF. Conclusions It is crucial to identify AF in preventing ocular infarction. This study revealed that AF was identified as a risk factor in patients with CRAO and vice versa.
Co-Authors Alberta, Ivana Beatrice Angelia, Maria Haryady, Stefanny Pratama, Kevin Gracia Stefanie, Airina