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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Cermin Dunia Kedokteran Journal of General Procedural Dermatology and Venereology Indonesia Ophthalmologica Indonesiana
Alberta, Ivana Beatrice
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Retinopati Klorokuin dan Hidroksiklorokuin Alberta, Ivana Beatrice; Tri Ekaputri, Maria Vania; Amita, Angela Shinta Dewi
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1038.997 KB) | DOI: 10.55175/cdk.v47i10.1081

Abstract

Klorokuin dan hidroksiklorokuin kerap digunakan sebagai tatalaksana berbagai penyakit autoimun, infeksi malaria, dan kini menjadi salah satu obat penanggulangan darurat Coronavirus Disease-19 (COVID-19). Kedua obat ini berpotensi sebagai antiinflamasi dan antivirus. Namun penggunaannya sering menimbulkan berbagai efek samping seperti pada jantung, saraf, saluran pencernaan, dan juga mata. Efek samping pada mata dapat berupa toksisitas retina yang dapat berakhir menjadi retinopati ireversibel. Guna menghindari cacat permanen, diperlukan pencegahan yang tepat dengan mengenali faktor risiko dan skrining, serta pemantauan ketat penggunaan obat.Chloroquine and hydroxychloroquine are often used as a treatment for autoimmune disease, malaria infection, and now become an emergency drug for Coronavirus Disease-19 (COVID-19). Both are potential anti-inflammatory and antiviral agents. However, potential various side effects to the heart, nerves, gastrointestinal tract, and also eyes must be considered. Side effects on the eyes are retinal toxicity which can end up as irreversible retinopathy. Proper prevention is needed by recognizing risk factors and screening, as well as strict monitoring of drug use.
The association between blotting paper application and severity of acne vulgaris among medical students Alberta, Ivana Beatrice; Hermawan, Melyawati; Ali, Soegianto
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Acne vulgaris is an inflammatory condition of the pilosebaceous glands caused by various factors including excessive excretion of sebaceous glands. Excess sebum can be reduced using oil blotting paper (OBP), a thin paper with microspores that absorb the oil on the face. This study was conducted to determine the association between OBP application and sebum excretion according to the Oily Skin Self- Assessment Scale (OSSAS) questionnaire and acne severity according to the Global Acne Grading System (GAGS) questionnaire. Methods: This experimental study was conducted in 2017 among 60 students aged 17–22 years at the Faculty of Medicine, Atma Jaya Catholic University of Indonesia, recruited by purposive sampling. Data on sebum excretion and the degree of AV severity before and after intervention were analyzed using the chi- square test with a significant level of p < 0.05. Results: Before intervention, 11 (18.3%) students had dry skin, 23 (38.3%) had slightly dry skin, 17 (28.4%) had slightly oily skin, and 9 (15%) had oily skin. The prevalence of AV was 100%, with 48 (80%) students having mild severity and the remaining having moderate severity. There was no effect of using OBP on sebum excretion (p = 0.211); however, an improvement was noted on GAGS raw data score (p < 0.001). Conclusion: AV is an inflammatory disease of the pilosebaceous glands, and one of the etiologies is excessive sebum excretion, which can be reduced using OBP. This study demonstrated that OBP application did not reduce sebum excretion statistically but could improve the severity of AV.
ARTIFICIAL INTELLIGENCE IN OPHTHALMOLOGY: CHALLENGES AND READINESS IN INDONESIA Dien Putri, Asnhy Anggun; Alberta, Ivana Beatrice; Ciputra, Fredy
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol. 6 No. 2 (2023): Al-Iqra Medical Journal: Jurnal Berkala Ilmiah Kedokteran
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/aimj.v6i2.10951

Abstract

Artificial Intelligence (AI) has been increasingly used in various fields of medicine. It involves the development of algorithms and computer programs that can learn from and adapt to data, enabling machines to perform tasks without explicit human instructions. The ultimate goal of AI is to create machines that can think and reason like humans. AI has the potential to transform the field of ophthalmology, which leads to improved patient care. This study aims to examine the current state of AI in ophthalmology, the challenges facing its adoption in Indonesia, and the opportunities for growth and development in this field. A literature search was conducted using PubMed, Google Scholar, and Proquest to identify relevant studies and reports related to AI in ophthalmology. AI in ophthalmology has been studied extensively in the field of screening, diagnosis, management, and predicting outcomes. Some studies proved that AI has a relatively high accuracy in diagnosing certain eye diseases, as demonstrated by its high sensitivity and specificity. However, high accuracy does not necessarily mean that AI is ready for clinical practice, especially in Indonesia. Several challenges include the risk of bias, the absence of standard assessment methods for AI, inadequate infrastructure and regulation, ethics, and sociocultural aspects. AI has the potential to revolutionize the ophthalmology field in Indonesia, leading to better patient outcomes and more efficient healthcare systems.
Karakteristik Klinis dan Kesintasan Keratoplasti Tembus Optik di Layanan Tingkat Tersier di Indonesia: Studi Retrospektif 4 Tahun Widyawati, Syska; Gondhowiardjo, Tjahjono D.; Nora, Rina La Distia; Harniza, Yulika; Samira, Cut Putri; Alberta, Ivana Beatrice
Majalah Kedokteran Indonesia Vol 72 No 6 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.6-2022-785

Abstract

Introduction: Purpose, to evaluate patient demographic characteristics, indications and variables related to penetrating keratoplasty (PK) survival. Study design, this study was retrospective case series. Methods: We trace all medical records of PK patients from 2015 to 2018 in Cipto Mangunkusumo Hospital Jakarta. The traced variables were indications of surgery, corneal vascularization, previous failed graft, glaucoma after PK, and other complication. PK survival rate is shown in the Kaplan Meier curve using SPSS v20.0. Results: A total of 214 patients underwent PK (men 67.3%, woman 32,7%) with mean age of 42.11 (0-85) years were included in this study. Three most common indications of keratoplasty were corneal scar (32.7%), infectious corneal ulcer (25.5%), and failed graft (19.2%). The overall graft survival rate for PK is 61.7%. The mean graft survival time was 14.388 ± 0.580 months (95% CI; 13.252-15.524). Conclusion: The graft survival rate for penetrating optic keratoplasty was 61.7%. Establishing an appropriate early diagnosis, reasonable surgical procedures, close monitoring, and early detection of complications with proactive interventions lead to better outcomes. Further research is needed to determine the relationship between the risk factors for corneal graft failure.
THE ASSOCIATION BETWEEN ATRIAL FIBRILLATION AND CENTRAL RETINAL ARTERY OCCLUSION: A META-ANALYSIS AND SYSTEMATIC REVIEW: Oral Presentation - Observational Study - General practitioner Amelia, Yufilia Suci; Alberta, Ivana Beatrice; Angelia, Maria; Pratama, Kevin Gracia
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/qdf5xw44

Abstract

Introduction Central retinal artery occlusion (CRAO) is a condition where the central retinal artery is blocked. Atrial Fibrillation (AF) is commonly associated with retinal embolism that originates anywhere between the heart and the ophthalmic artery. This study aims to explore the incidence of AF in CRAO. Methods A systematic search was performed in three databases: Pubmed, EBSCO host, and Proquest. Newcastle-Ottawa Scale was used to assess the risk of bias in the study included. Results Our systematic review comprises six studies, 4 studies included CRAO patients as the study population and AF as the endpoint, and the other 2 studies with CRAO as the endpoint. Meta-analysis of the first group resulted in a significantly favorable AF incident after CRAO with an odds ratio (OR) of 1.46 (95% CI 1.17-1.81, p=0.0007). The second metaanalysis supports CRAO with an OR of 4.86 (95% CI 2.30-10.28, p<0.0001). Discussion Our study indicates that AF is a significant risk factor for CRAO. Extended cardiac monitoring may play a crucial diagnostic role in CRAO patients, and longer-term monitoring (23 years) may be a reasonable option as part of the diagnostic workup. Short-term monitoring alone may fail to detect a significant proportion of patients with underlying AF. Conclusions It is crucial to identify AF in preventing ocular infarction. This study revealed that AF was identified as a risk factor in patients with CRAO and vice versa.
Co-Authors Amelia, Yufilia Suci Amita, Angela Shinta Dewi Angelia, Maria Ciputra, Fredy Dien Putri, Asnhy Anggun Harniza, Yulika Hermawan, Melyawati Nora, Rina La Distia Pratama, Kevin Gracia Samira, Cut Putri Soegianto Ali Tjahjono D. Gondhowiardjo Tri Ekaputri, Maria Vania Widyawati, Syska