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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Cermin Dunia Kedokteran
Agustina, Angelia
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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Kombinasi Paramedian Forehead Flap dan Hinge Flap pada Basalioma Nasal dengan Defek Kompleks Agustina, Angelia; Pribadi, Sweety
Cermin Dunia Kedokteran Vol 47, No 3 (2020): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (917.074 KB) | DOI: 10.55175/cdk.v47i3.373

Abstract

Basalioma merupakan kanker kulit non-melanoma yang paling sering ditemukan. Basalioma umumnya tumbuh lambat, menyebabkan destruksi lokal, jarang bermetastasis. Penyakit ini berkembang pada area terpapar sinar UV, umumnya di hidung. Tulisan ini melaporkan kasus seorang pria 48 tahun dengan basalioma di daerah nasal. Dilakukan eksisi luas dan rekonstruksi paramedian forehead flap, dikombinasi dengan hinge flap dan cartilage graft. Hasil pemeriksaan patologi anatomi menunjukkan basalioma berpigmen, dengan ulserasi fokal keratotik, batas irisan bebas. Manajemen yang tepat dapat meningkatkan kualitas hidup baik secara estetik maupun mencegah kekambuhan. Basalioma is the most common non-melanoma skin cancer. Basalioma is generally a slow growing tumor, locally destructive and rarely metastasizes. This tumor developed mostly in areas exposed to UV, nose is the most common location. This paper reports a 48-year-old male with basalioma in the nasal area. Extensive excision was carried out followed by reconstruction with paramedian forehead flap combined with hinge flaps and auricular cartilage graft. Pathological examination shows pigmented basalioma with focal keratotic ulceration, edge of incision was free from tumor. Appropriate management is needed to improve aesthetically and to prevent recurrence.
Assessing the Efficacy of Dengue Vaccine: A Comprehensive Literature Review Agustina, Angelia; Alamanda, Cut Nur Cinthia
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 2 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i2.2415

Abstract

Dengue fever remains a major global public health issue, especially in tropical nations like Indonesia, where cases of Dengue Hemorrhagic Fever (DHF) continue to increase annually. Despite extensive efforts in mosquito vector control programs, the transmission of dengue fever continues. World Health Organization (WHO) recommends vaccination as a potential option that can be used in endemic areas such as Indonesia. This literature review aims to collect and analyze the latest evidence on the efficacy and effectiveness of dengue vaccines based on findings from current relevant research. Dengvaxia, TAK-003, and TV003/TV005 are potential vaccines to provide immunity and prevent dengue infections with efficacy of Dengvaxia, DENV 3 and 4 70-80%, DENV 1 and 2 40-50%; TAK-003 seropositive 76.1%, seronegative 66.2% and TV003/TV005 seropositive 89.2% seronegative 73.6% (1-6). Additionally, TV003/TV005 can be used for travelers to endemic areas, as a single-dose administration and has been shown to provide immunity regardless of serostatus.
Co-Authors Alamanda, Cut Nur Cinthia Pribadi, Sweety