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Fingerprint Study of Curcuma xanthorrhiza Rhizome by High Performance Thin Layer Chromatography (HPTLC) Wikara, Tina; Sulistiowaty, Anny; Murhandini, Sri; Usia, Tepy
Jurnal Jamu Indonesia Vol. 1 No. 2 (2016): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v1i2.13

Abstract

The rhizome of Curcuma xanthorrhiza Roxb is intensively used in Indonesia as traditional medicine. It is widely used for hepatoprotective and anti inflammatory activities. To ensure the quality of its extract, we have studied the fingerprint or phytochemical analysis. This research was aimed to produce a chromatogram profile of the rhizome by HPTLC. The HPTLC fingerprint chromatogram of C. xanthorrhiza rhizome was performed using HPTLC plate of silica gel 60 F254 as the stationary phase and chloroform-methanol (97:3) as the mobile phase. Spot detection was carried out by TLC photo documentary system at 254 and 366 nm and TLC scanner at 427 nm. The developed method was validated according to ICH guidelines by determination of specificity and precision. We found that the specifity and precission of the method were met the acceptance criteria. In conclusion, the developed method is valid and could be used for quality control and standardization of herbal medicine containing C. xanthorrhiza rhizome.
Tren Kepatuhan Pelaku Usaha Bidang Kosmetik di Indonesia Astuti, Sri; Wikara, Tina; Nurhayati, Sri; Sari, Evi Ratna; Carolina, Rotua Uli; Rahmita, Galuh Zhafirah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 2 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i2.741

Abstract

Compliance of business actors with regulations and standards such as the Good Manufacturing Practice (GMP) and regulations on the distribution, advertising and labelling of cosmetics is a crucial aspect in ensuring the safety and quality of cosmetic products to protect public health. This study aimed to assess the level of compliance of cosmetics business actors with regulations and standards in Indonesia. This quantitative study analyzed secondary data from the Indonesian FDA (BPOM)’s risk-based supervision of production and distribution facilities, advertising, and labelling across 34 provinces from 2019–2023. Each year, 4270–7,054 facilities were inspected and classified as compliant or non-compliant, and compliance proportions were calculated. The results were weighted using the Analytical Hierarchy Process (AHP) to produce a compliance index categorized into four levels: excellent (90.01–100), good (66.67–90), fair (33.34–66.66), and poor (0–33.33). The results of the analysis showed that the compliance index of cosmetics businesses for five years ranged from 71.62 to 83.79 and was classified as good: 82.79 (2019), 80.96 (2020), 75.41 (2021), 71.62 (2022), and 83.79 (2023). The index trend showed a fluctuating pattern from year to year, with the highest value recorded in 2023.
Analysis of Public Knowledge, Attitudes, and Practices in Food and Drug Selection in Indonesia Wikara, Tina; Astuti, Sri; Nurhayati, Sri; Carolina, Rotua Uli; Sari, Evi Ratna
Kesmas Vol. 20, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

As consumers, the public plays a vital role in ensuring the safe and appropriate use of products. This study aimed to assess awareness of food and drug safety and quality among the Indonesian population. Using a cross-sectional survey, the authors measured public awareness across three key dimensions: knowledge, attitudes, and practices. Data were collected from 20,610 respondents aged 17–65 years from 34 provinces in Indonesia. The survey approach employed a three-stage stratified sampling design. Data were collected through structured face-to-face interviews, and the results were presented as an index ranging from 0 to 100 (low to high awareness). The respondents demonstrated good knowledge (92.85), attitudes (90.46), and practices (80.97). The average overall Awareness Index was 88.09. The authors observed significant variations by region, age, education, and occupation, but not by sex. The gap between knowledge and attitudes, and practices can be regarded as a public health concern. Awareness of food and drug safety and quality that does not manifest in behavioral practices does not protect consumers from harm.