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Low-intensity aerobic cycle ergometer effects on lung function of myasthenia gravis patients: A randomized controlled trial Amalina, Nabila; Poerwandari, Dewi; Handajani, Noor I.; Sudibyo, Devi A.; Melaniani, Soenarnatalina
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.844

Abstract

Patients with generalized myasthenia gravis (MG) often show restrictive spirometry results. Although regular exercise and physical fitness are linked to better respiratory function, there is limited research assessing the effects of aerobic exercise on lung function in MG patients. The aim of this study was to analyze the effect of low-intensity aerobic exercise using a cycle ergometer on lung function parameters in MG patients. A randomized controlled trial with pre- and post-test was conducted at the Medical Rehabilitation Outpatient Clinic of Dr. Soetomo General Academic Hospital in Surabaya, Indonesia, in 2023. MG patients classified as I−IIb based on the Myasthenia Gravis Foundation of America (MGFA) classification were recruited and randomly divided into treatment and control groups. The treatment group was given low-intensity aerobic exercise using a cycle ergometer, education on lifestyle changes, and breathing exercises (deep and pursed lip breathing). Lung function parameters, including forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and forced expiratory volume ratio (FEVR), were then measured. Measurements were conducted before and after eight weeks of low-intensity aerobic cycle ergometer exercise and compared with those of a control group. A total of 17 MG patients were included in this study. The results showed a significant increase in FVC in the treatment group (p=0.003), whereas no significant change in the control group (p=0.068). A significant increase in FEV1 was observed both in the treatment (p=0.029) and the control group (p=0.016). There was no improvement in FEVR in either group. After the intervention, significant differences were observed in FVC (p=0.009) and FEV1 (p=0.029) between the treatment and control groups. There was no significant difference in FEVR values after the intervention between both groups (p=0.491). In conclusion, eight weeks of low-intensity aerobic cycle ergometer exercise led to significant improvements in FVC and FEV1 among MG patients.
Prototipe Perpustakaan Virtual Museum & Galeri Sby*Ani Dengan Design Innovation Methode Amalina, Nabila; Susetyarto, Martinus Bambang
Metrik Serial Teknologi dan Sains Vol. 3 No. 1 (2022)
Publisher : Konsorsium Cendekiawan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51616/teksi.v3i1.277

Abstract

Virtual architecture has unlimited space. The space is one of the answers to the fulfillment of space needs on limited land in the real world. The development of the library at the SBY*Ani Museum and Gallery is actually thinking about using virtual architecture to meet the demands of providing an alternative space that can functionate the library to keep books and collections, with low cost and sustain quality layout management, and flexible visiting times for readers/borrowers. Purpose of the research was finding a library prototype that give a pleasant space experience and user friendly, also having an impact on the sustainability of library management which was combaining architecture of the virtual world and of the real world. The research used the Design Innovation Method (Kumar V., 2013) which has seven different activity modes for design innovation, namely: Sense Intent, Know Context, Know People, Frame Insights, Explore Concepts, Frame Solutions, and Realize Offerings. The result of the research was a virtual library prototype at the SBY*Ani Museum and Gallery which is an effort to develop the architecture of the library space in the virtual world combined with architecture in the real world. The development was carried out to accommodate space needs, especially a pleasant space experience and user friendly space that provide books and collections, and to design other spaces that can be built in the virtual world, with attractive interior designs, user friendly products, safe, comfortable, and flexible for readers/borrowers. By this research process which was using the Design Innovation Method, at least three prototypes were found, namely D0, D1, and D2. All three have been tested and are being evaluated to establish the findings of the research. This research has limitations in terms of funding and research work time, in which researchers must combine the research work schedule with the work schedule for the SBY*Ani Museum and Gallery construction project, as well as the situation and conditions for the application of restrictions on community activities due to the Covid-19 pandemic. The research value was unique in terms of the research methods and findings, originality, and useful impact that can be felt by the community and owner of the Museum and Gallery SBY*Ani