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PROFIL MANIFESTASI KLINIS DAN LABORATORIUM PASIEN DEMAM TIFOID DI RS PKU BANTUL Devita, Ninda; Riski, Muhammad Syafiq; Marufi, Rian; Habibah, Ulil Albab
Jurnal Kedokteran Universitas Palangka Raya Vol 11 No 2 (2023): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v11i2.10753

Abstract

Typhoid fever can give various clinical manifestations and laboratoryThis study is a retrospective descriptive study using medical record data. The data collected was clinical manifestations and laboratory then presented in a frequency distribution diagram. A total of 72 typhoid fever patients at PKU Hospital Bantul in 2014-2015 were included as subjects. A 53% of the subjects were women. The mean age was 32 ± 14 years. The main symptoms were fever (99%), gastrointestinal symptoms (91%), headache (37%), muscle aches (11%), and cough (8%). The dominant physical examination found hepatomegaly and dirty tongue (19% and 5%). The main laboratory abnormalities were increased SGOT (46%), SGPT (39%), anemia (26%), and leukopenia (22%) It was concluded, typhoid fever patients often found fever, gastrointestinal symptoms, headache accompanied by anemia, leukopenia, and elevated liver enzymes in laboratory tests.
Changes In Hematological Parameters Of Typhoid Fever Patients At Pku Bantul Hospital, Yogyakarta Devita, Ninda; Riski, Muhammad Syafiq; Marufi, Rian
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 12 No. 2 (2024): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v12i2.31587

Abstract

Background: Typhoid fever causes changes in the results of hematological examination. Many factors influence hematological changes in thyphoid fever these changes. Obective: This study aims to determine the relationship between several patient characteristics and hematological changes in typhoid fever patients at PKU General Hospital, Bantul, Yogyakarta. Method: This is a cross-sectional study. A total of 85 patients diagnosed with typhoid fever at PKU General Hospital were included in this study. Hematological examination results and subject characteristics (sex, age, duration of fever) were taken from medical records. The relationship between subject characteristics and hematological changes was analyzed by Chi-Square test using Medcalc software. Result:  Anemia and leukopenia were found to be higher in female subjects (34.88% vs 17.14%; p=0.03 and 20.45% vs 9.75%; p=0.04). Age ≥45 years are associated with the incidence of anemia (18.61 vs 40.00; p=0.03). Leukopenia and thrombocytosis was higher in patients with a duration of fever < 1 week (p=0.02 and p=0.000). Conclusion: Hematological changes in thyphoid fever are influenced by gender, age, and duration of fever before admission to the hospital. Keywords: Typhoid fever, Hematological changes, Factor influenced