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All Journal Medica Hospitalia NUSANTARA: Jurnal Pengabdian Kepada Masyarakat
Ardiani, Tiara
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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Peningkatan Perilaku Hidup Bersih Dan Sehat (PHBS) Sebagai Intervensi Pencegahan Kejadian Stunting Di Rw 03 Desa Sirnagalih Kecamatan Tamansari Kabupaten Bogor Tahun 2024 Zakiah, Lela; Awalia, Mutia; Putri, Ega; Nurhayati, Siti; Ardiani, Tiara; Nabila, Wanda
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 2 (2024): Mei : Jurnal Pengabdian Kepada Masyarakat
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/nusantara.v4i2.2617

Abstract

In our nation, stunting remains a serious health issue that has to be addressed. According to WHO data from 2020, Indonesia has the second-highest rate of stunted children under five in Southeast Asia, with a rate of 31.8%. The Community Midwifery Care Intervention Practice seeks to reduce stunting by educating and raising public knowledge of the use of Clean and Healthy Living Behavior (PHBS) as an intervention. With a sample size of thirty, this study employed the lecture technique with booklets and posters. Respondents completed questionnaires that were distributed as part of the data collection process. According to the research findings, there was a significant influence on promoting clean and healthy living behavior (PHBS) as an intervention to prevent stunting, as evidenced by the pretest value which showed that the greatest number of people with poor knowledge was 21 (70.0%), and the posttest results indicated that the greatest number of people with good knowledge was 27 (90.0%). The t value for this effect was 4.835. To sum up, there is an impact on raising awareness of Clean and Healthy Living Behavior (PHBS) as a stunting prevention strategy.  
Hepatotoksik terkait Obat Antituberkulosis pada Pasien Tuberkulosis dan Koinfeksi Tuberkulosis-HIV Azmi, Rizki Nur; Ardiani, Tiara; Siami, Sahra
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 1 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.932 KB) | DOI: 10.36408/mhjcm.v9i1.650

Abstract

BACKGROUND : The side effect of antituberculosis drugs that is toxic to liver cells, called hepatotoxic, needs to be a concern in the treatment of tuberculosis. The presence of these unwanted side effects poses a challenge in treatment because it can lead to discontinuation oh therapy or a change in regimen. Coinfection with HIV is also thought to increase the potential for hepatotoxicity of antituberculosis drugs. OBJECTIVE: This study aims to determine the incidence of hepatotoxicity of antituberculosis drugs in patients with tuberculosis and tuberculosis-HIV coinfection. METHOD : This study is an observational study with a cross sectional design, which was conducted in one of the hospitals in Samarinda City. Sources of research data came from patient medical record in 2018 – 2020. There was 53 tuberculosis patients and 53 tuberculosis-HIV coinfection patients. Differences in live enzyme values (AST and ALT) and severity in the two groups were analyzed by Mann-Whitney and Chi-Square tests. RESULT : The average value of AST and ALT in tuberculosis-HIV coinfection patients were higher than patients without HIV infection, which is AST 127,1 µ/L and ALT 100,7 µ/L. The highest degree of severity experienced by the patient was grade 3 (severe hepatotoxicity). Tuberculosis-HIV coinfection patients with grade 3 severity were 22,6% and tuberculosis patients were 9,4%. The values of liver enzymes and the severity of hepatotoxicity in the two groups of patients were statistically significant with p value < 0,05. CONCLUSION : Tuberculosis-HIV coinfection patients tend to have a higher incidence of hepatotoxicity related to antituberculosis drugs than those without HIV infection.
Co-Authors Awalia, Mutia Azmi, Rizki Nur Nabila, Wanda Putri, Ega Siami, Sahra Siti Nurhayati Zakiah, Lela