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All Journal JSFK (Jurnal Sains Farmasi & Klinis) Medica Hospitalia Jurnal Ilmu Kesehatan Jurnal Riset Inossa : Media Hasil Riset Pemerintahan, Ekonomi dan Sumber Daya Alam Prosiding University Research Colloquium Jurnal Farmasi SYIFA Media Farmasi E-Amal: Jurnal Pengabdian Kepada Masyarakat
Azmi, Rizki Nur
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Hepatotoksik terkait Obat Antituberkulosis pada Pasien Tuberkulosis dan Koinfeksi Tuberkulosis-HIV Azmi, Rizki Nur; Ardiani, Tiara; Siami, Sahra
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 1 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.932 KB) | DOI: 10.36408/mhjcm.v9i1.650

Abstract

BACKGROUND : The side effect of antituberculosis drugs that is toxic to liver cells, called hepatotoxic, needs to be a concern in the treatment of tuberculosis. The presence of these unwanted side effects poses a challenge in treatment because it can lead to discontinuation oh therapy or a change in regimen. Coinfection with HIV is also thought to increase the potential for hepatotoxicity of antituberculosis drugs. OBJECTIVE: This study aims to determine the incidence of hepatotoxicity of antituberculosis drugs in patients with tuberculosis and tuberculosis-HIV coinfection. METHOD : This study is an observational study with a cross sectional design, which was conducted in one of the hospitals in Samarinda City. Sources of research data came from patient medical record in 2018 – 2020. There was 53 tuberculosis patients and 53 tuberculosis-HIV coinfection patients. Differences in live enzyme values (AST and ALT) and severity in the two groups were analyzed by Mann-Whitney and Chi-Square tests. RESULT : The average value of AST and ALT in tuberculosis-HIV coinfection patients were higher than patients without HIV infection, which is AST 127,1 µ/L and ALT 100,7 µ/L. The highest degree of severity experienced by the patient was grade 3 (severe hepatotoxicity). Tuberculosis-HIV coinfection patients with grade 3 severity were 22,6% and tuberculosis patients were 9,4%. The values of liver enzymes and the severity of hepatotoxicity in the two groups of patients were statistically significant with p value < 0,05. CONCLUSION : Tuberculosis-HIV coinfection patients tend to have a higher incidence of hepatotoxicity related to antituberculosis drugs than those without HIV infection.
Pengetahuan dan Perilaku Swamedikasi pada Masyarakat Kota Samarinda Azmi, Rizki Nur; Hanifa, Deasy Nur Chairin; Suwarno, Kafka Navisa; Maharani, Adelya
Media Farmasi Vol 20 No 1 (2024): Media Farmasi Edisi April 2024
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v20i1.404

Abstract

Self-Medication Knowledge and Behavior in Samarinda City Communities Improper use of drugs in self-medication or self-medication practices can cause serious health problems, such as the emergence of drug side effects, dependence, and others. Good knowledge and behavior can result in rational self-treatment and reduce the dangerous risks of the practice. The aim of this research is to analyze the knowledge and behavior of the people of Samarinda City. The research design used was cross sectional using a questionnaire containing questions to assess knowledge and self-medication behavior. Data collection was carried out in August – September 2023 by distributing questionnaires in various public areas in Samarinda City. The sampling technique used was purposive sampling. The research results obtained from 330 respondents who were the research sample, with the dominant characteristics being 68.2% women, 98.2% adults (19 - 44 years old) and 87.9% having a high school education (SMA). The level of self-medication knowledge was higher in the poor category (79.1%) and the level of self-medication behavior was in the good category (83.3%). Penggunaan obat yang tidak tepat dalam praktik swamedikasi atau pengobatan mandiri dapat menyebabkan masalah kesehatan yang serius, seperti munculnya efek samping obat, ketergantungan dan lain-lain. Pengetahuan dan perilaku yang baik dapat menghasilkan pengobatan mandiri yang rasional dan mengurangi risiko berbahaya dari praktik tersebut. Tujuan penelitian ini ialah menganalisis pengetahuan dan perilaku masyarakat Kota Samarinda. Desain penelitian yang digunakan adalah cross sectional dengan menggunakan kuesioner yang berisi pertanyaan untuk menilai pengetahuan dan perilaku swamedikasi. Pengumpulan data dilakukan pada bulan Agustus – September 2023 dengan menyebarkan kuesioner di berbagai public area di Kota Samarinda. Teknik sampling yang digunakan ialah purposive sampling. Hasil penelitian didapatkan 330 responden yang menjadi sampel penelitian, dengan karakteristik dominan pada perempuan sebanyak 68,2%, berusia dewasa (19 – 44 tahun) sebanyak 98,2% dan memiliki pendidikan terakhir Sekolah Menengah Atas (SMA) sebanyak 87,9%. Tingkat pengetahuan swamedikasi lebih banyak pada kategori buruk (79,1%) dan tingkat perilaku swamedikasi pada kategori baik (83,3%).
EVALUASI DOSIS DAN PROFIL PENGOBATAN PADA PASIEN DIABETES MELLITUS TIPE 2 KOMPLIKASI NEFROPATI DI RUMAH SAKIT DI KOTA SAMARINDA Ruslan, Rainhard Duta Pradana; setiawan, Roni; Hanif, Deasy Nur Chairin; Azmi, Rizki Nur
Jurnal Riset Inossa : Media Hasil Riset Pemerintahan, Ekonomi dan Sumber Daya Alam Vol. 5 No. 01 (2023): Juni
Publisher : Badan Perencanaan Pembangunan Daerah, Penelitian dan Pengembangan Kota Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54902/jri.v5i01.100

Abstract

The number of Diabetes Milletus cases in the city of Samarinda is 3.04%. One of the complications of uncontrolled DM can cause nephropathy. DM patients with diabetic nephropathy are described as having chronic albuminuria of 300 mg/24 hours on 2 visits 3 to 6 months. The purpose of this study was to look at the profile and treatment evaluation of patients with Diabetes Mellitus Type 2 complications of nephropathy at a hospital in Samarinda City. The method in this study is non-experimental observational with a descriptive design. With a cross-sectional approach using retrospective data, namely looking at data based on medical records of patients with Diabetes Mellitus Type 2 complications of nephropathy at a hospital in Samarinda City. The results of a study conducted at Samarinda City Hospital with a sample of 94 type 2 DM patients with nephropathy complications who were treated at inpatient installations from January 2021 to March 2022. The percentages were obtained based on gender, namely men (45.74%) ) and women (54.26%). The age range of patients with nephropathy DM is between 18-60 years with the most incidence being 41-60 (57.45%). The treatment profile obtained the greatest results using insulin, namely novorapid insulin (43.43%), lantus (19.74%) ), levemir (13.16%). while the oral drug, sulfonylrea (Gliquidone) 30 mg (13.16%). In this study there were 789 (97.65%) correct doses of 808 drugs and 19 (2.35%) incorrect doses. drug cases that require adjustment of drug dosage because it is influenced by the GFR value. Keywords: Type 2 Diabetes Mellitus, Dosage Evaluation, Nephropathy Complications, Treatment Profile.
PENGOLAHAN NUGGET IKAN KEMBUNG SEBAGAI UPAYA PENINGKATAN STATUS GIZI ANAK Azmi, Rizki Nur; Hanifa, Deasy Nur Chairin; Putra, Aditya Rian Riady; Sarah, Aulia; Regita, Geta
E-Amal: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 2: Mei-Agustus 2024
Publisher : LP2M STP Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47492/eamal.v4i2.3412

Abstract

Kurangnya gizi dalam periode 1000 hari pertama kehidupan merupakan penyebab utama terjadi stunting yang berdampak pada banyak permasalahan kesehatan terhadap masa depan anak. Protein hewani seperti ikan kembung memiliki potensi dalam pemenuhan gizi anak. Ikan ini juga dapat diolah menjadi bentuk nugget yang disukai anak. Dalam kegiatan ini dilakukan pengabdian kepada masyarakat berupa sosialisasi pembuatan nugget ikan kembung. Kegiatan dilakukan di Kelurahan Sidodadi, Kota Samarinda, Provinsi Kalimantan Timur. Peserta kegiatan meliputi orang tua dan pengasuh balita di daerah tersebut. Hasil kegiatan didapatkan adanya peningkatan pengetahuan yang signifikan dari uji statistik dengan nilai p 0,005 dan tingkat kesukaan dalam uji hedonik terhadap nugget ikan kembung didapatkan suka pada aspek warna, aroma, tekstur, rasa, dan tampilan secara keseluruhan
Analysis of Risk Factors For Anemia and Neutropenia Post-Chemotherapy in Patients with Acute Lymphoblastic Leukemia at Samarinda Hospital Aisyah, Siti; Azmi, Rizki Nur
Jurnal Ilmu Kesehatan Vol 12 No 2 (2024): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chemotherapy is the main therapy in the treatment of acute lymphoblastic leukemia and can change the body's hematological parameters during therapy. Haematological side effects that commonly occur after chemotherapy include anemia and neutropenia. The aim of this study was to determine the risk factors for anemia and neutropenia in patients with acute lymphoblastic leukemia after chemotherapy. This research is retrospective analytic with cross sectional data collection methods. The type of data used is secondary data from medical records of patients diagnosed with acute lymphoblastic leukemia. Data were analyzed using SPSS version 25.0. The research results obtained from this study were that there was a significant relationship between chemotherapy regimen and the incidence of anemia in acute lymphoblastic leukemia patients (p=0.001), and a significant relationship was found between age and chemotherapy regimen and the incidence of neutropenia in acute lymphoblastic leukemia patients (p= 0.005 and p=0.011). The conclusion obtained is that risk factors for chemotherapy regimens have a significant relationship between the incidence of anemia. In addition, the risk factors of age and chemotherapy regimen have a significant relationship between the incidence of neutropenia. Risk factors aged 12-25 years have the opportunity to increase the risk of neutropenia by 0.231 times greater than risk factors for chemotherapy regimens.
Hubungan Tingkat Kepatuhan Meminum Obat Dengan Nilai Tekanan Darah Pada Pasien Hipertensi Geriatri Di Puskesmas Segiri Kota Samarinda Fathimah, Umi; Azmi, Rizki Nur; Abdissalam, Erfan
Jurnal Farmasi SYIFA Vol 3 No 2 (2025): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v3i2.776

Abstract

Hipertensi merupakan salah satu penyakit yang paling sering muncul di negara berkembang seperti Indonesia. Penyakit hipertensi pada geriatri diindikasikan ketika hasil pengukuran tekanan darah sistolik ≥ 150 mmHg dan tekanan darah diastolik ≥ 90 mmHg. Prevalensi hipertensi di Kalimantan Timur berdasarkan diagnosis dokter sebanyak 39,30% dari jumlah total penduduk usia ≥18 tahun. Sedangkan angka kasus hipertensi berdasarkan data Dinas Kesehatan Kota Samarinda  tahun 2024 sebanyak 69.156 kejadian. Penyebab ketidakpatuhan lansia dalam meminum obat antihipertensi diantaranya disebabkan oleh kesibukan dalam bekerja, penurunan daya ingat terkait waktu pemberian obat, efek samping dari pengobatan seperti mengantuk, pusing, rasa mual selama mengonsumsi obat antihipertensi serta penghentian pengobatan saat keadaan membaik. Tujuan penelitian ini untuk mengetahui adanya hubungan tingkat kepatuhan meminum obat dengan nilai tekanan darah pada pasien hipertensi di Puskesmas Segiri Kota Samarinda. Penelitian ini merupakan jenis penelitian kuantitatif yang dirancang dengan menggunakan studi cross sectional. Teknik pengambilan sampel yang digunakan adalah purposive sampling dengan jumlah sampel minimum 61 responden. Analisis yang digunakan adalah uji Spearman Rank Corellation. Data yang didapatkan dari pengisian kuesioner Morisky Medication Adherence Scale (MMAS-8) dan nilai tekanan darah di analisis univariat dan bivariat. Hasil yang di dapatkan adalah nilai p = 0,000 dengan nilai koefisien korelasi 0,438. Hasil tersebut disimpulkan bahwa terdapat hubungan cukup kuat antara kepatuhan meminum obat terhadap nilai tekanan darah pasien hipertensi geriatri di Puskesmas Segiri Kota Samarinda.
Pengaruh Pemberian Edukasi oleh Apoteker terhadap Peningkatan Pengetahuan Masyarakat tentang Penatalaksanaan Nyeri pada Geriatri Cholisoh, Zakky; Azmi, Rizki Nur; Malik, Irhamadi
Prosiding University Research Colloquium Proceeding of The 11th University Research Colloquium 2020: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Usia geriatri akan merubah kondisi fisik dan profil farmakokinetik farmakodinamik. Meningkatnya sarana kesehatan (klinik dan apotek) yang terdapat di Kabupaten Sukoharjo berdampak pada penggunaan obat masyarakat yang secara bebas melakukan upaya untuk memelihara dan meningkatkan kesehatan sendiri (swamedikasi). Swamedikasi tanpa dasar pengetahuan yang tepat dapat meningkatkan kemungkinan terjadinya medication error. Intervensi edukasi obat oleh Apotekerterbukti dapat menurunkn angka kejadian medication error. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh sesi edukasi oleh apoteker terhadap pengetahuan masyarakat Dusun Karangtengah Ngadirejo Kartasura Sukoharjo tentang penatalaksanaan nyeri pada penyakit otot dan tulang dengan obat dan tanpa obat serta bagaimana cara memilih obat penghilang rasa nyeri yang aman. Penelitian dilakukan dengan cara memberikan intervensi edukasi kepada respoden. Evaluasi tertulis dengan memberikan kuesioner dilakukan sebelum dan sesudah intervensi. Kuesioner berisi pertanyaan tertutup tentang penyebab gout, rematik, dan osteoarthritis, perbedaan antara ketiganya; serta penatalaksanaan nyeri karena penyakit otot dan tulang. Analisis data dilakukan dengan membandingkan skor pengetahuan sebelum dan sesudah intervensi dengan uji t berpasangan. Hasil penelitian menunjukkan adanya peningkatan pengetahuan masyarakat tentang penyakit rematik dan penatalaksanaan nyeri sebelum dan sesudah edukasi secara signifikan (uji t berpasangan p< 0,001) dengan rata-rata nilai pengetahuan sebelum penyuluhan adalah 55,0±23,1 dan sesudah penyuluhan adalah 82,0±15,4. Berdasarkan hasil penelitian tersebut terbukti bahwa sesi edukasi oleh apoteker dapat meningkatkan pengetahuan masyarakat tentang penatalaksanaan nyeri secara signifikan. Hal ini diharapkan akan memunculkan kesadaran yang dapat merubah tingkah laku atau pola pikir seseorang agar dapat memperoleh obat yang efektif dan aman serta dapat menggunakan obat nyeri dengan baik dan benar.
Antiepileptic Drug Prescribing Patterns and Seizure Control Among Outpatients with Epilepsy at a Public Hospital in Indonesia Faqih, Muhammad; Cholisoh, Zakky; Seftiyanti , Nirma; Nugraheni, Ambar Yunita; Azmi, Rizki Nur
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 2 (2025): J Sains Farm Klin 12(2), August 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.2.156-166.2025

Abstract

Background: Epilepsy affects nearly 50 million people globally, including approximately 700,000–1.4 million in Indonesia, with 70,000 new cases reported annually. Objective: This study aimed to determine antiepileptic drug (AED) prescribing patterns and to examine their association with seizure control outcomes in patients with epilepsy. Methods: A descriptive cross-sectional analysis was conducted using 185 outpatient prescriptions. Data on patient demographics, seizure frequency, and AED regimens were collected. Patterns of monotherapy and polytherapy were analyzed descriptively, and seizure control was compared using chi-square analysis. Results: Of the patients evaluated, 48.6% were male and 51.4% female. Monotherapy was prescribed in 51.4% of patients, predominantly valproic acid (VPA) and phenytoin (PHT). Polytherapy was used in 48.6% of patients, with the most common combinations being VPA + carbamazepine (CBZ) and PHT + VPA. Seizure-free control within six months was achieved in 34.6% of patients. A significant association was found between therapy regimen and seizure control (p = 0.040), with poor control more frequent in polytherapy (73.3%) than monotherapy (57.9%). Patients on polytherapy had twice the risk of poor seizure control (OR = 2.00; 95% CI: 1.08–3.72). Conclusion: Valproic acid remains the most prescribed AED for monotherapy, while phenytoin–valproic acid combinations are frequent in polytherapy. Polytherapy was associated with poorer seizure control, highlighting the importance of individualized AED selection and rational drug utilization in epilepsy management
Co-Authors Abdissalam, Erfan Ambar Yunita Nugraheni Ardiani, Tiara Cholisoh, Zakky Fathimah, Umi Hanif, Deasy Nur Chairin Hanifa, Deasy Nur Chairin Maharani, Adelya Malik, Irhamadi Muhammad Faqih Putra, Aditya Rian Riady Regita, Geta Roni Setiawan Ruslan, Rainhard Duta Pradana Sarah, Aulia Seftiyanti , Nirma Siami, Sahra Siti Aisyah Suwarno, Kafka Navisa