Sigumonrong, Yacobda Hamonangan
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SURVIVAL ANALYSIS OF PEDIATRIC WILMS TUMOR BASED ON RISK STRATIFICATION Andy; Sigumonrong, Yacobda Hamonangan
Indonesian Journal of Urology Vol 29 No 1 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i1.712

Abstract

Objective: This study aims to determine prognostic factors of WT patient in Adam Malik Hospital, Medan. Material & Methods: at Adam Malik Hospital, Medan. Univariate and multivariate Cox regression analyses were performed to determine independent prognostic factors for WT. The primary endpoint of this study were patients’ overall survival (OS) obtained by performing Kaplan-Meier analysis on significant variables. Results: From the univariate Cox regression analysis, gender was found to be the sole significant factor (HR = 0.218, p = 0.005) with males have a higher hazard ratio. The multivariate Cox regression analysis yielded age of diagnosis (HR = 13.860, p = 0.014) and incomplete tumor removals (HR = 0.056, p = 0.008). Kaplan-Meier analysis were performed on three significant variables mentioned before. Only gender yielded a significant Mantel-Cox log-rank score (p = 0.002) with male patients were found to have better survivability (which median survival 476 days compared to females’ 11 days). The survival of the boys was 45.45% while all of the girls did not survive until the cut-off. Conclusion: Three prognostic factors, including children’s gender, age of diagnosis, and tumor removal status, were confirmed to be prognostic factors for the overall survival of children with WT. Further studies covering broader demographic areas were suggested to confirm significant results.
Spontaneous resolution of haematuria and clot retention after covid-19: a case report Wijaya, William Saputra; Prapiska, Fauriski Febrian; Sigumonrong, Yacobda Hamonangan; Adhyatma, Kharisma Prasetya
Medistra Medical Journal (MMJ) Vol 1 No 2 (2024): Medistra Medical Journal (MMJ)
Publisher : Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/mmj.v1i2.2062

Abstract

COVID-19 has been associated with a hypercoagulable state which leads to an increase risk of thromboembolic events in blood vessels. The nature of renal manifestation of COVID-19 usually involves microvascular thrombosis resulting kidney injury. Major renal artery thrombosis in COVID-19 is considered quite rare. We present a case of a patient with recurrent haematuria and clot retention post PCNL for nephrolithiasis with an spontaneous resolution of complaints after infection with COVID-19. The patient was found to have a high D-dimer, fibrinogen values, and an elevated partial thromboplastin time. We reviewed existing literature to assess whether or not these events are related to one another