Claim Missing Document
Check
Articles

Found 2 Documents
Search

Fibroblast Growth Factor-23 (FGF-23) in Patients with Regular Hemodialysis: A Risk Factor for Restless Legs Syndrome Harahap, Rasyidah Hasan; Riri Andri Muzasti; Alwi Thamrin Nasution
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (781.417 KB) | DOI: 10.32734/jetromi.v2i3.4293

Abstract

Background: Restless Legs Syndrome (RLS) is one of the most common sleep disturbance problems in dialysis patients. In this study, we would like to explore some of bone and mineral marker disorder especially fibroblast growth factor-23 (FGF-23)and its correlation with RLS in regular hemodialysis patients. Methods: This is a cross sectional study design involving 71 respondents with chronic kidney disease that already had regular hemodialysis at Haji Adam Malik Hospital Medan. Status of RLS in this patients were being evaluated according to the International Restless Leg Syndrome Study Group (IRLSG) by interviewing and laboratory examination of FGF-23, hemoglobin (Hb), serum iron (SI), total iron binding capacity (TIBC), transferrin saturation (TSAT), serum ferritin, calcium (Ca) and phosphate (P) level. Results: Of all study subjects, 26 respondents (34.6%) diagnosed with RLS. Bivariate analysis result showed that there is a relationship between FGF-23, hemoglobin, phosphate, and transferrin saturation level with RLS. Logistic regression analysis used to see the most dominant factor of all. Conclusion This study conclude that increase in FGF-23 levels can increase the risk of RLS. However, FGF-23 is not the most dominant risk factor for RLS in regular hemodialysis patients.
The Association Between Sociodemographic Factors, Onset and Duration of Ilness With Personal and Social Performances in Outpatient Chronic Schizophrenia in Stabilization Phase Alyya Andini Syafitri; Vita Camellia; M. Yusuf Rachmatsyah; Riri Andri Muzasti
Jurnal Psikiatri Surabaya Vol. 14 No. 2 (2025): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i2.53018

Abstract

Introductions: Schizophrenia is a serious mental illness that affects a person’s daily quality of life. Various factors such as sociodemographic factors, onset, and duration of illness can be related to the quality of life in schizophrenia. The parameter for measuring quality of life in schizophrenia patients is the Personal and Social Performance Scale (PSP Scale). This study is aim to analyze the association between sociodemographic factors, onset, and duration of illness in outpatient chronic schizophrenia patients in the stabilization phase with their personal and social performances. Methods: This study is an observational analytical research with a cross-sectional study design. The sample of this study was outpatient chronic schizophrenia stabilization phase in a mental hospital of North Sumatra Province, Prof. Dr. Muhammad Ildrem Medan Mental Hospital and selected using the purposive sampling method, where after calculating using the multivariate analysis predictive concept method, the number of samples needed was 80 samples. The data used is primary data obtained directly from respondents. The analysis used is univariate, bivariate and multivariate analysis with chi-square. Results: There is a significant relationship between the level of personal and social function with education level (p=0.002), marital status (p=0.001), and employment (p=0.002) in outpatient chronic schizophrenia stabilization phase. Conclusion: The results of multivariate analysis showed that the most significant variables with personal and social function in outpatient chronic schizophrenia stabilization phase were marital status (OR=4.395), employment (OR=4.220), and education level (OR= 0.220) in order of the variables with the greatest strength of influence.