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All Journal PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Holistik Jurnal Kesehatan
Nabigha, Zehan Aura
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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COMPARISON OF THE NUMBER OF ERYTHROCYTES IN 3 ML, 2 ML, & 1 ML OF BLOOD SAMPLES WITH K2EDTA ANTICOAGULANTS AFTER A 4-HOUR DELAY IN THE DR. H. ABDUL MOELOEK BANDAR LAMPUNG HOSPITAL Syuhada; Priyayi, Hemas; Putri , Bella Tania; Nabigha, Zehan Aura; Triwahyuni, Tusy
PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS Vol. 1 No. 2 (2022): APRIL
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/comorbid.v1i2.144

Abstract

Background: The volume of blood samples, especially the number of erythrocytes in laboratory examinations, has an important role in determining the results of the diagnosis, in this case pre-analytic errors often occur so that a definite diagnosis will be difficult to establish. Therefore, research on the comparison between the results of the examination of the number of erythrocytes in the volume of blood samples of 3 mL, 2 mL, and 1 mL after being delayed for 4 hours with K2EDTA anticoagulant helps to determine a definite diagnosis from laboratory tests, one of which is the count of the number of erythrocytes. Research purpose: it aims to identify the comparison of erythrocytes in the volume of blood sample 3 ml, 2 ml, and 1 ml with k2edta anticoagulant after postponed for four hours. Research methods: the study uses primary data with hematology analyzer in rsud Dr.abdul moeloek bandar lampung. This type of research is a quantitative, using observational analtic design with a cross sectional view and with consecutive method, through hematology analysis using a alayzer mindray bc-3600 hematology. The research has 50 respondents. Results: the results of erythrocytes comparison between blood volume 3 ml, 2 ml and 1 ml (ml) with k2edta anticoagulant after 4 hours have different results but statistically the results have the same with 3 ml, that show the lowest result. Conclusion: there is no significant differences between the examunation of the erythrocytes with the volume of blood sample 3 mL, 2 mL, and 1 mL in the vacutainer k2edta tube after postponed for four hours.
Faktor yang berhubungan dengan kejadian tuberkulosis paru pada anak (usia 0-14 tahun) Nabigha, Zehan Aura; Aryawati, Wayan; Aryastuti, Nurul
Holistik Jurnal Kesehatan Vol. 19 No. 12 (2026): Volume 19 Nomor 12
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i12.759

Abstract

Background: Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and can affect all ages, including children. The incidence of pulmonary TB in children is influenced by various factors, such as host, agent, and environment. These factors include exclusive breastfeeding, Bacille Calmette-Guérin (BCG) immunization status, low birth weight (LBW), socioeconomic status, and history of contact with TB patients. Rajabasa Indah Community Health Center ranked third in terms of TB cases in Bandar Lampung in 2022, with 125 cases in adults and 40 cases in children. If risk factors are not addressed, the number of new cases will continue to increase. Purpose: To identify factors associated with the incidence of pulmonary TB in children aged 0-14 years. Method: This was a quantitative study with a case-control design. The sampling technique used purposive sampling, with a total of 120 children participating, divided into 30 cases and 90 controls. Data analysis was performed using chi-square tests and multiple logistic regression. Results: In the case group, 76.7% had a history of exclusive breastfeeding, 70% had received BCG immunization, 63.3% had no history of low birth weight (LBW), 53.2% were from low socioeconomic status, and 60% had no history of contact with TB patients. Meanwhile, in the control group, 68.9% had a history of exclusive breastfeeding, 94.4% had received BCG immunization, 91.1% had no history of low birth weight (LBW), 56.7% were from high socioeconomic status, and 86.7% had no history of contact with TB patients. There was a significant association between a history of low birth weight (p = 0.001), BCG immunization status (p = 0.001), and a history of contact with TB patients (p = 0.004) and the incidence of pulmonary TB in children. The dominant factor influencing the incidence of pulmonary TB in children was BCG immunization status (p = 0.002). Conclusion: There is a significant association between BCG immunization status, history of low birth weight (LBW), and history of contact with TB patients with the incidence of pulmonary TB in children. BCG immunization is a dominant factor in TB prevention, therefore, the public is encouraged to ensure that children receive complete basic immunizations, especially BCG from birth, to prevent pulmonary TB and more severe TB cases. Suggestion: Further research can be conducted with a larger sample size to provide information regarding the description of risk factors for TB incidents in children.   Keywords: Children; Bacille Calmette-Guérin (BCG) Immunization; Low Birth Weight (LBW); Tuberculosis.   Pendahuluan: Tuberkulosis (TB) merupakan penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis dan dapat menyerang segala usia, termasuk anak-anak. Kejadian TB paru pada anak dipengaruhi oleh berbagai faktor, seperti host, agent, dan lingkungan, yang meliputi pemberian ASI eksklusif, status imunisasi Bacille Calmette-Guérin (BCG), berat badan lahir rendah (BBLR), status sosial ekonomi, serta riwayat kontak dengan penderita TB. Puskesmas Rajabasa Indah menempati urutan ketiga dalam jumlah kasus TB terbanyak di Bandar Lampung pada tahun 2022, dengan 125 kasus pada orang dewasa dan 40 kasus pada anak-anak. Jika faktor risiko tidak dicegah, jumlah kasus baru akan terus bertambah. Tujuan: Untuk mengetahui faktor-faktor yang berhubungan dengan kejadian TB paru pada anak usia 0-14 tahun Metode: Penelitian kuantitatif dengan rancangan case-control. Teknik pengambilan sampel dilakukan dengan purposive sampling, dengan total 120 anak sebagai partisipan, yang terbagi menjadi kelompok kasus sebanyak 30 anak dan kelompok kontrol sebanyak 90 anak. Analisis data dilakukan menggunakan uji chi-square dan regresi logistik ganda. Hasil: Pada kelompok kasus, 76.7% memiliki riwayat ASI eksklusif, 70% telah mendapatkan imunisasi BCG, 63.3% tidak memiliki riwayat BBLR, 53.2% berasal dari status sosial ekonomi rendah, dan 60% tidak memiliki riwayat kontak dengan penderita TB. Sementara pada kelompok kontrol, 68.9% memiliki riwayat ASI eksklusif, 94.4% telah mendapatkan imunisasi BCG, 91.1% tidak memiliki riwayat BBLR, 56.7% berasal dari status sosial ekonomi tinggi, dan 86.7% tidak memiliki riwayat kontak dengan penderita TB. Terdapat hubungan yang signifikan antara riwayat BBLR (p = 0.001), status imunisasi BCG (p = 0.001), dan riwayat kontak dengan penderita TB (p = 0.004) dengan kejadian TB paru pada anak. Faktor dominan yang berpengaruh terhadap kejadian TB paru pada anak adalah status imunisasi BCG (p = 0.002). Simpulan: Terdapat hubungan yang signifikan antara status imunisasi BCG, riwayat BBLR, dan riwayat kontak dengan penderita TB dengan kejadian TB paru pada anak. Imunisasi BCG merupakan faktor dominan dalam pencegahan TB, sehingga masyarakat diimbau untuk memastikan anak-anak mendapatkan imunisasi dasar lengkap, terutama BCG sejak lahir, guna mencegah kejadian TB paru dan kasus TB yang lebih berat. Saran: Penelitian selanjutnya dapat dilakukan dengan jumlah sampel yang lebih banyak diperlukan guna memberikan informasi terkait gambaran faktor resiko kejadian TB pada anak.   Kata Kunci: Anak; Berat Badan Lahir Rendah (BBLR); Imunisasi Bacille Calmette-Guérin (BCG);  Tuberkulosis.
Co-Authors Aryastuti, Nurul Aryawati, Wayan Priyayi, Hemas Putri , Bella Tania syuhada Tusy Triwahyuni