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All Journal Buletin Kedokteran dan Kesehatan Prima International Journal of Health and Pharmaceutical (IJHP)
Wilvia, Wilvia
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Results from an Obesity Model in White Male Wistar Rats After Administration of Telang Flower (Clitoria Ternatea) Extract on Pancreatic Function and Histopathological Characteristics Yulisandra Rini, Weni; Azmi Tanjung, Fahrul; Wilvia, Wilvia
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 2 (2024): May 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.323

Abstract

Diabetes mellitus (DM) is a chronic disease affecting 95% of diabetics, characterized by high blood glucose levels due to decreased insulin production. Bioactive chemicals from plants like butterfly pea flower and Clitoria Ternatea can potentially treat DM, inhibit carbohydrate-digesting enzymes, and potentially regenerate pancreatic beta cells. This study tests butterfly pea flower extract on obesity-related pancreatic function in white rats. In obese rats given varied dosages of butterfly pea flower extract, the study evaluates pancreatic tissue histopathology and ethanol extract properties. The study examines male Wistar rats' acclimatization before treatment with butterfly pea flower extract, a high-fat diet, and butterfly pea flower extract, comparing the effects of the extract on rats. Pancreatic function is examined using enzymes amylase and lipase. Histopathological observation of pancreatic organs involves several steps, including fixation, washing, infiltration, embedding, cutting, attaching, deparaffinization, dealcoholization, staining, mounting, and scoring. A post-test-only control group design compared butterfly pea flower extract and pancreatic function in male white rats. Butterfly pea flower extract improved pancreatic histology in obese white rats at 600mg/KgWB, closer to the normal group. The extract contains secondary metabolites that repair cell tissue damaged by the rats' high-fat diet and obesity.
The impact of work commitment and motivation on the performance of nurses at Muyang Kute Hospital, Bener Meriah Regency Jumiati, Jumiati; Hartono, Hartono; Ginting, Rapael; Wilvia, Wilvia; Setiawan, Linda Novelgia; Chiuman, Veranyca; Yuni, Yuni; Pratiwi, Tari Dwi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6678

Abstract

This study investigates the influence of work commitment and motivation on nurse performance at Muyang Kute Regional General Hospital, Bener Meriah Regency, Indonesia, using an analytical survey with a cross-sectional design. A total sampling of 49 nurses from inpatient wards participated in the study. Data were collected via questionnaires measuring work commitment (Guttman scale), work motivation (Guttman scale), and nurse performance (Likert scale). Bivariate analysis using Fisher’s Exact Test revealed a significant association between both work commitment and nurse performance (p = 0.000) and work motivation and nurse performance (p = 0.003). Nurses with high commitment demonstrated significantly higher performance, with 81.8% exhibiting high performance compared to 25.9% of nurses with low commitment. Similarly, nurses with high work motivation showed significantly higher performance, with 70.4% categorized as high performers compared to 27.3% of those with low motivation. These findings highlight the critical role of work commitment and motivation in enhancing nurse performance, suggesting that interventions aimed at improving these factors could lead to significant improvements in healthcare delivery at Muyang Kute Hospital. The study underscores the importance of addressing factors that influence nurse commitment and motivation to optimize patient outcomes and organizational success.
Co-Authors Azmi Tanjung, Fahrul Chiuman, Veranyca Hartono Hartono Jumiati Jumiati Pratiwi, Tari Dwi Rapael Ginting Setiawan, Linda Novelgia Yulisandra Rini, Weni YUNI, YUNI