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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Buletin Kedokteran dan Kesehatan Prima
Chiuman, Veranyca
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Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Other

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EFFECT OF ANDALIMAN (Zanthoxylum Acanthopodium) NANOHERBAL EXTRACT ADMINISTRATION ON LIVER FUNCTION AND LIVER HISTOPATHOLOGY OF STREPTOZOTOCIN-INDUCED DIABETIC MALE WISTAR RATS Permata Khaira, Azzuhra; Ginting, Chrismis Novalinda; Chiuman, Linda; Chiuman, Veranyca; Sihombing, Bungaran
International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Vol 6 No 3 (2024)
Publisher : The Islamic Education and Multiculturalism Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47006/ijierm.v6i3.350

Abstract

Abstract : Background: Diabetes Mellitus is a systemic disease with hyperglycemia, and can cause Non-Alcoholic Fatty Liver Disease (NAFLD). Nanoherbal of andaliman has an antioxidant effect on the body. Objective: This study aims to determine the effect of nanoherbal of andaliman on liver function and liver histopathology. Method: This study used an experimental method with a post-test-only control group design of 30 male wistar rats induced with streptozosin, divided into 6 groups with nano herbal of andaliman as the testing material. Results: There is no difference in the liver function (SGOT and SGPT) between the groups that are given andaliman and the ones that do not with the p values of 0,183 and 0,449 (p>0,05). There is a difference in liver histopathology between the groups with the p-value of 0,03 (p<0,05), it also shows that the groups that are given andaliman experienced liver degeneration. Conclusion: Nanoherbal of andaliman has the antioxidant effect that acts as hepatoprotection, but also includes some substances that can cause damage to the liver cells. The writer suggested adding more samples, doing the pre-test and post-test examinations, and also analyzing the effect of the steroid and terpenoid in andaliman on the liver cells.
The impact of work commitment and motivation on the performance of nurses at Muyang Kute Hospital, Bener Meriah Regency Jumiati, Jumiati; Hartono, Hartono; Ginting, Rapael; Wilvia, Wilvia; Setiawan, Linda Novelgia; Chiuman, Veranyca; Yuni, Yuni; Pratiwi, Tari Dwi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6678

Abstract

This study investigates the influence of work commitment and motivation on nurse performance at Muyang Kute Regional General Hospital, Bener Meriah Regency, Indonesia, using an analytical survey with a cross-sectional design. A total sampling of 49 nurses from inpatient wards participated in the study. Data were collected via questionnaires measuring work commitment (Guttman scale), work motivation (Guttman scale), and nurse performance (Likert scale). Bivariate analysis using Fisher’s Exact Test revealed a significant association between both work commitment and nurse performance (p = 0.000) and work motivation and nurse performance (p = 0.003). Nurses with high commitment demonstrated significantly higher performance, with 81.8% exhibiting high performance compared to 25.9% of nurses with low commitment. Similarly, nurses with high work motivation showed significantly higher performance, with 70.4% categorized as high performers compared to 27.3% of those with low motivation. These findings highlight the critical role of work commitment and motivation in enhancing nurse performance, suggesting that interventions aimed at improving these factors could lead to significant improvements in healthcare delivery at Muyang Kute Hospital. The study underscores the importance of addressing factors that influence nurse commitment and motivation to optimize patient outcomes and organizational success.
Anti-inflammatory Activity of Lemon Pepper Nanoemulsion on Carrageenan-Induced Male Wistar Rat Chiuman, Linda; Sebayang, Dwi Putri Agita; Chiuman, Veranyca; Suhartomi, Suhartomi
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6292

Abstract

Lemon pepper does not only have a unique taste but also has some active compounds, which has anti-inflammatory activity. This study intended to investigate the anti-inflammatory effect of lemon pepper nanoemulsion on carrageenan-induced Wistar rats. This experimental study used Twenty-five male Wistar rats that were grouped into five different groups, including control, standard, lemon pepper nanoemulsion dose of 25, 50, and 75 mg/ kgBW. Initially, all rats received air injection in the back area for 5 days to form an air pouch. After that, all rats were injected with 1% carrageenan solution, and received treatment based on the groups for 48 hours via oral route. Then, it counted the number of white blood cells by Giemsa Stain that was expressed as a number of cells per High Power Field (HPF). The increasing of Lemon pepper nanoemulsion dose significantly decreased the number of leucocytes in the carrageenan aspiration after 48 hours of treatment (P-Value < 0.001). The lowest number of leucocytes was found in the Lemon Pepper Nanoemulsion dose of 75 mg/kgBW (2.40 leukocytes per HPF). Hence, it can be deducted that the lemon pepper nanoemulsion has an anti-inflammatory effect, especially at a dose of 50-75 mg/kgBW.
Co-Authors Chiuman, Linda Ginting, Chrismis Novalinda Hartono Hartono Jumiati Jumiati Permata Khaira, Azzuhra Pratiwi, Tari Dwi Rapael Ginting Sebayang, Dwi Putri Agita Setiawan, Linda Novelgia Sihombing, Bungaran SUHARTOMI . Wilvia, Wilvia YUNI, YUNI