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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan Majalah Patologi Indonesia Ebers Papyrus
Puspita Eka Wuyung
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan

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Pengaruh Pemberian Ekstrak Etil Asetat Ulva fasciatadelile dan Turbinaria decurrensbory terhadap Laju Pertumbuhan Tumor Kelenjar Susu Padamencit C3h Thamrin Wikanta; Vita Fitria Handayani; Lestari Rahayu; Asri Pratitis; Puspita Eka Wuyung
Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 6, No 1 (2011): Juni 2011
Publisher : Balai Besar Riset Pengolahan Produk dan Bioteknologi Kelautan dan Perikanan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/jpbkp.v6i1.92

Abstract

ABSTRACTBreast cancer is the second mostly found disease after cervix cancer to Indonesian woman. Research on the effect of Ulva fasciata Delile and Turbinaria decurrensBory ethyl acetate extract feeding on the Adenocarcinoma mammaecell proliferation on C3H mice has beenconducted. Thirty experimental mice were devided into 6 treatment groups, i.e.: K-I, negative control; K-II, solvent control; K-III, given U. fasciata ethyl acetate extract dose of 41.32 mg/20 g BW (body weight); K-IV, given U. fasciataethyl acetate extract dose of 82.64 mg/20 g BW; K-V, given T. decurrensethyl acetate extract dose of 24.29 mg/20 g BW; and K-VI, given T. decurrens ethyl acetate extract dose of 48.59 mg/20 g BW. All treatments were given during 21 days. The mice body weight and tumor volume were measured and collected subsequently at every two days. Tumor doubling time was calculated at the end of research. Results showed that there wasa highly tumor growth inhibition on the K-IV shown by the high doubling time value. Tumor growth inhibition decreased according to the sequence as follows: K-IV (U. fasciata dose of 82.64 mg/20g BW), K-V (T. decurrensdose of 24.29 mg/20 g BW), K-VI (T. decurrensdose of 48.59 mg/20 g BW) which equal to K-II (solvent control), K-III (U. fasciatadose of 41.32 mg/20 g BW), K-I(negative control).
Co-Authors Asri Pratitis Budiana Tanurahardja DEWI IRAWATI Dewi Jantika Dian Sari Oethia Vathonati Fita Ferdiana Hartono Tjahjadi Hendy Setyo Yudhanto Lestari Rahayu Minarma Siagian Nurjati Chairani Siregar Reni Angeline Rina Effendi Salinah Salinah Susy Olivia Thamrin Wikanta Vita Fitria Handayani