Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Majalah Patologi Indonesia Jurnal MedScientiae
Freciyana Boedijono
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Ekspresi Programmed Death Ligand-1 (PD-L1) pada Seminoma Testis sebagai Potensi Faktor Prognostik Freciyana Boedijono; Budiana Tanurahardja; Ria Kodariah
Majalah Patologi Indonesia Vol 29 No 3 (2020): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (594.889 KB) | DOI: 10.55816/mpi.v29i3.448

Abstract

BackgroundThe prognosis of testicular seminoma cases which failed to be cured with conventional therapy is poor. Several recurrent eventsafter chemotherapy were also found. PD-L1 is expressed in various types of malignancy and tumor infiltrating lymphocytes (TILs)and its role is known as a prognostic factor. This study was conducted to determine the role of PD-L1 expression seminoma indetermining overall survival (OS) and progression free survival (PFS).MethodsThis is a retrospective cohort study with survival analysis. Clinical data were obtained from medical record in RSUPN CiptoMangunkusumo since January 2011-December 2016 and observed for 2 years. Histopathological data were obtained fromAnatomical Pathology Department and PD-L1 immunohistochemical staining were performed.ResultsA significant correlation between PD-L1 expression in tumor cells with 2-year OS (p=0.023) and PFS (p=0.002) in testicularseminoma was found. No significant correlation between PD-L1 expression in TILs with 2-year OS (p=0.235) and PFS (p=0.111).We also found significant correlations between PD-L1 expression of tumor cells and TILs with PFS (p=0.019). A significantcorrelation between stage with 2-year OS (p=0.010) and PFS (p=0.000) and lymph node metastases with 2-year OS (p=0.010) andPFS (p=0.000).ConclusionPD-L1 expression of testicular seminoma cells were significantly correlated with OS and PFS. There were no statistically significantassociations between PD-L1 expression in TILs with OS and PFS.
Characteristics and Histopathological Features of Breast Tumor Patients at RSUD dr. Chasbullah Abdulmadjid Bekasi City 2019-2023 Angeline, Reni; Husseynia Muharrani; Shintia Christina; Freciyana Boedijono
Jurnal MedScientiae Vol. 3 No. 3 (2024): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3501

Abstract

Globocan data for 2020 in the world, breast cancer cases are in first place with 2,261,419 cases, the death rate is in fifth place with 684,994 people. In Indonesia, in 2020 breast cancer ranks first. In the 2020 Bekasi City health profile data, there were 92 cases (4.8%) of breast lumps/tumors, compared to 2019 was 6.37%, but when compared to 2018, there was an increase in cases of 4.18%. The aim of this study was to find out information on the characteristics and histopathological features of breast tumor patients at RSUD dr. Chasbullah Abdulmadjid Bekasi City in 2019-2023. This research is a descriptive study with a cross-sectional method, using secondary data from anatomical pathology archives. In the study, a total of 488 cases of benign and malignant breast tumors were found, consisting of: 176 cases in 2019, 97 cases in 2020, 77 cases in 2021, 69 cases in 2022, and 69 cases in 2023. Description of tumor incidence Most benign breasts at the age of 20-29 years, location of upper lateral quadrant tumors, clinical diagnosis of benign breast tumors and histopathological type of mammary fibroadenoma. Meanwhile, the description of the incidence of malignant breast tumors is highest at age > 50 years, location of the upper lateral quadrant tumor, clinical diagnosis and histopathological type of invasive ductal carcinoma.
Co-Authors Angeline, Reni Budiana Tanurahardja Husseynia Muharrani Ria Kodariah Ria Kodariah Shintia Christina