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All Journal Indian Journal of Forensic Medicine & Toxicology
Entedhar R. Sarhat
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Public Health

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Evaluation of Lipocalin-2 and Visfatin, and Vitamin (D,C, and E) in Serum of Diabetic Patients with Chronic Periodontitis Anas Qahtan Hamdi; Entedhar R. Sarhat; Nagham Hasan Ali; Thuraia Rifaat Sarhat
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14578

Abstract

Objective: The aim of the present study is to verify the hypothesis that salivary and serum lipocalin-2and visfatin, and vitamin (D,C, and E) used as indicators for chronic periodontitis among DMT2 patients.Subjects and methods: We enrolled 41 type 2 diabetic patients with chronic periodontitis -18 males and 23females, aged 60± 14 years and 49 controls- 26 males and 23 females, aged 61.8 ± 12.5 years. Blood sampleswere collected after an overnight fast and routine biochemical parameters such as glucose, lipocalin-2 andvisfatin, and vitamin (D,C, and E)were determined in all samples. Data were considered significant at a levelof p < 0.05.Periodontitis status was established using classic clinical parameters, Plaque index (PI), gingivalindex (GI), probing depth (PD) and clinical attachment level (CAL). Results: 1) The mean serum of bloodglucose, Visfatin, and LCN2 were higher in patients group than in those with normal control group (P<0.001for all comparisons) ; 2) patients with had a lower Vitamin D,C, and E than those with a normal group (P <0.001 for all comparisons).Conclusions: The activity of lipocalin-2 and visfatin in saliva and serum can beuseful in diagnosis, monitorization and treatment of this disease. Further studies are needed to elucidate therole of lipocalin-2 and visfatin in periodontitis and systemic disease interactions.
The Study of Hemodialysis on the Change Rate of Serum Osteopontin, Sialic Acid, and Nitric Oxide Levels Entedhar R. Sarhat; Takea Shaker Ahmed; Mahde Salih Hamad; Rajaa S. Najim; ThuraiaRifaat Sarhat; Kasim Sakran Abass
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15686

Abstract

Objective : Chronic renal failure (CRF) is one of the most prevalent diseases of human societies, especially in Iraq. Despite all advances that have been made so far, hemodialysis with all its complications is being applied as the novel treatment strategy for such individuals.Osteopontin (OPN) is a multi-functional secreted glycoprotein that plays a crucial role in and inflammatory process.Our aim was to ascertain whether circulating osteopontin,sialic acid ,and NO levels are altered in patients with CRF before and after dialysis.Design and Methods: A total of 126 patients with HD were enrolled in this study. Serum OPN levels were measured using a commercial enzymelinked immunosorbent assay kit.Results: Osteopontin and Sialic acid levels were significantly higher in haemodialysed CKD patients than predialysed CKD patients and normal healthy controls. The levels of NO was significantly lower in CRF patients pre HD when compared with healthy controls and significantly increased in post HD as compared to pre HD. Conclusion: In our study, OPN SA, NO were found to be a valuable marker of severity of CKD.
Altered Serum Marker of Adipokines Profile in Breast Cancer Women Shaimaa Essa Ahmed; Entedhar R. Sarhat; Neda Awni; ThuraiaRifaat Sarhat; Kasim Sakran Abass
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15697

Abstract

Co-Authors Anas Qahtan Hamdi Kasim Sakran Abass Mahde Salih Hamad Nagham Hasan Ali Neda Awni Rajaa S. Najim Shaimaa Essa Ahmed Takea Shaker Ahmed Thuraia Rifaat Sarhat ThuraiaRifaat Sarhat