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Asih Budiastuti
Department Of Dermatology, Faculty Of Medicine, Diponegoro University, Semarang, Indonesia
Health Professions Medicine & Pharmacology Public Health

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PENGARUH PEMAKAIAN MASKER MADU TERHADAP DERAJAT KEPARAHAN AKNE VULGARIS Fitriani, Ulfah; Budiastuti, Asih; Widodo, Aryoko
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 8, No 3 (2019): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.825 KB) | DOI: 10.14710/dmj.v8i3.24510

Abstract

Latar belakang: Akne vulgaris merupakan kelainan kulit kronik pada unit pilosebasea yang ditandai dengan seborrhea, formasi komedo terbuka dan tertutup, pustula dan papula yang erimatus, serta pada kasus yang berat dapat disertai pustul yang dalam dan pseudokista. Madu memiliki senyawa hidrogen peroksida (H2O2) yang efektif sebagai zat antibakteri. Sifat antibakteri madu membantu mengatasi infeksi pada luka sedangkan aksi anti inflamasinya dapat mengurangi nyeri yang berpengaruh pada proses penyembuhan. Tujuan: Mengetahui adanya pengaruh pemberian madu terhadap derajat keparahan Akne Vulgaris. Metode: Penelitian ini merupakan studi klinis dengan desain randomized pre and post test control group. Subjek penelitian adalah mahasiswi Fakultas Kedokteran Universitas Diponegoro Semarang yang memenuhi kriteria inklusi. Subyek penelitian diacak kedalam kelompok kontrol dan perlakuan, masing-masing kelompok terdiri dari 20 subyek dan lama penelitian selama 4 minggu atau. Data yang diperoleh merupakan data primer dengan mengisi kuisioner, menghitung jumlah lesi AV dan menentukan derajat keparahan AV. Hasil: Lesi total AV awal penelitian kedua kelompok tidak berbeda bermakna (p=0,301), begitu pula dengan lesi total AV akhir penelitian (p=0,229). Perbedaan total lesi AV awal (20,95±10,98) dan akhir (12,32±12,23) kelompok kontrol berbeda bermakna (p<0,005). Terdapat penurunan bermakna (p<0,001) dari lesi AV awal (25,11±13,32)  dan akhir (15,21±12,54) pada kelompok perlakuan. Delta lesi kelompok kontrol dan perlakuan juga tidak berbeda bermakna (p=0,698). Pada akhir penelitian, derajat keparahan AV antara kedua kelompok didapatkan hasil akhir tidak berbeda bermakna (p=1,000). Kesimpulan: Tidak didapatkan hubungan bermakna antara pemakaian masker madu dengan derajat keparahan AV selama 4 minggu.Kata kunci: Akne vulgaris, derajat keparahan, masker madu.
Association between Bubble Tea Consumption and Prevalence of Acne Vulgaris Subagio, Devina; Budiastuti, Asih; Riyanto, Puguh; Aryoko Widodo, Yulian Ludovicus
Cermin Dunia Kedokteran Vol 48, No 7 (2021): Infeksi - [Covid - 19]
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.984 KB) | DOI: 10.55175/cdk.v48i7.1450

Abstract

Introduction: Acne vulgaris (AV) is one of the most common skin disorders among youth. A cross-sectional study was conducted to analyze the association between bubble tea consumption and the prevalence of acne vulgaris among medical students. Method: Subjects were obtained from consecutive sampling. There were 91 eligible subjects meeting inclusion criteria. Data was collected using questionnaires. Examinations were through observation of photographs of lesions. Chi-square analysis was conducted at a 95% confidence interval (p<0.05). Results: Data were collected from 91 medical students with mean age 19.62+0.98 year-old. The prevalence of acne was 58.2%; mostly in age 20 years (37.7%). There is a significant association between consumption of bubble tea and the prevalence of AV (p<0.001). Conclusion: Bubble tea consumption is associated with prevalence of acne vulgaris.Pendahuluan: Akne vulgaris merupakan salah satu penyakit kulit yang umum dialami pada dewasa muda. Metode: Penelitian observasional cross sectional untuk mengetahui asosiasi konsumsi bubble tea dengan kejadian akne vulgaris. Sampel diambil dengan metode consecutive sampling menghasilkan 91 mahasiswa yang memenuhi kriteria inklusi dan eksklusi. Pengambilan data primer dengan kuesioner. Pemeriksaan fisik observasi kulit responden dengan foto. Analisis data menggunakan uji Chi-Square dengan tingkat kemaknaan p<0,05. Hasil: Angka kejadian akne vulgaris adalah 58,2% dengan rata-rata usia 19.62+0.98; usia terbanyak penderita adalah 20 tahun (37,7%). Terdapat asosiasi bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris (p<0,001). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris.
MELATONIN CAN NOT SIGNIFICANTLY INCREASE PLATELET COUNT Tania Meysavira Fawzi; Lusiana Batubara; Asih Budiastuti; Taufik Eko Nugroho
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 3 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i3.29492

Abstract

Background: Burn injury defines as skin or tissue damage caused by heat, radioactivity, electricity, or chemicals. Burn injury have an impact on physiological homeostasis. Burn injury will cause an increase in free radicals, it can also cause changes in the platelet count. Melatonin has been proposed as burn supportive therapy because it acts as an antioxidant that can eliminate free radicals. Melatonin can increase the number of the platelets through the mechanism of increasing megakaryocyte fragmentation and modulating the cytokines involved in platelet production. Aim: Proving the effects of melatonin supplementation on the number of platelets in male Wistar rats with third degree of burn injury. Methods: This research was an experimental with randomized control group pre-post test design. Samples are 12 healthy male Wistar rats then randomly divide into two groups, control and experimental group. Each rat was induced 30% burn injury under anesthesia. Rats in control group were given placebo at 0, 8, and 16 hours after burn injury, while rats in experimental group were treated with melatonin intraperitoneal at 0, 8 and 16 hours after burn injury. Blood samples were collected from the retroorbital sinuses at 0, 3, and 24 hours. Data were analyzed statistically by Paired t-Test and Independent t-Test. Results: In control group, the number of platelets at 0-3 hours (p=0,024) and 0-24 hours (p=0,039) showed a significant decrease in platelet count. In experimental group, the number of platelets at 0-3 hours (p=0,047), 0-24 hours (0,015), 3-24 hours (p=0,04) showed a significant decrease in platelet count.Conclusions: Melatonin administration did not cause a significant increase of platelets number. Keywords: Burns, Platelet count, Melatonin
Association between Bubble Tea Consumption and Prevalence of Acne Vulgaris Devina Subagio; Asih Budiastuti; Puguh Riyanto; Yulian Ludovicus Aryoko Widodo
Cermin Dunia Kedokteran Vol 48, No 7 (2021): Infeksi - [Covid - 19]
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i7.1450

Abstract

Introduction: Acne vulgaris (AV) is one of the most common skin disorders among youth. A cross-sectional study was conducted to analyze the association between bubble tea consumption and the prevalence of acne vulgaris among medical students. Method: Subjects were obtained from consecutive sampling. There were 91 eligible subjects meeting inclusion criteria. Data was collected using questionnaires. Examinations were through observation of photographs of lesions. Chi-square analysis was conducted at a 95% confidence interval (p<0.05). Results: Data were collected from 91 medical students with mean age 19.62+0.98 year-old. The prevalence of acne was 58.2%; mostly in age 20 years (37.7%). There is a significant association between consumption of bubble tea and the prevalence of AV (p<0.001). Conclusion: Bubble tea consumption is associated with prevalence of acne vulgaris.Pendahuluan: Akne vulgaris merupakan salah satu penyakit kulit yang umum dialami pada dewasa muda. Metode: Penelitian observasional cross sectional untuk mengetahui asosiasi konsumsi bubble tea dengan kejadian akne vulgaris. Sampel diambil dengan metode consecutive sampling menghasilkan 91 mahasiswa yang memenuhi kriteria inklusi dan eksklusi. Pengambilan data primer dengan kuesioner. Pemeriksaan fisik observasi kulit responden dengan foto. Analisis data menggunakan uji Chi-Square dengan tingkat kemaknaan p<0,05. Hasil: Angka kejadian akne vulgaris adalah 58,2% dengan rata-rata usia 19.62+0.98; usia terbanyak penderita adalah 20 tahun (37,7%). Terdapat asosiasi bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris (p<0,001). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris.
Co-Authors Aryoko Widodo Aryoko Widodo, Yulian Ludovicus Devina Subagio Fitriani, Ulfah Lusiana Batubara Puguh Riyanto Puguh Riyanto Subagio, Devina Tania Meysavira Fawzi Taufik Eko Nugroho Yulian Ludovicus Aryoko Widodo