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All Journal Indian Journal of Forensic Medicine & Toxicology Neurona
Herlina Suryawati
Unknown Affiliation
Health Professions Medicine & Pharmacology Neuroscience Public Health

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The Relationship between theSeverity of Obstructive Sleep Apnea (OSA) and Tension-Type Headache Frequency Aprilia; Herlina Suryawati; M.I. Widiastuti; Aris Catur Bintoro; EndangKustiowati; Jimmy Eko Budi Hartono
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15288

Abstract

HUBUNGAN ANTARA KADAR SEROTONIN SERUM DENGAN FUNGSI KOGNITIF PADA PASIEN NYERI KEPALA TIPE TEGANG KRONIS Ega Primadona; Dwi Pudjonarko; Dani Rahmawati; Endang Kustiowati; Herlina Suryawati; Trianggoro Budisulystio
NEURONA Vol 38 No 1 (2020)
Publisher : PERDOSNI

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Abstract

Introduction: Chronic tension-type headache (CTTH) is a major health problem, although the previous data is very limited, especially in Indonesia. Cognitive disorders often occur in CTTH patients. In addition, stress factors (mental or physical), anxiety, depression, temperamental instability, that is, bigger emotional status are factors that can cause CTTH. Serotonin is involved in various behavioral functions, especially in the regulation of mood, aggressiveness and impulsiveness. Aim: To analyze the relationship between serotonin serum level with cognitive function on CTTH. Methods: This was a cross sectional study in the outpatient of neurological clinic dr. Kariadi Hospital Semarang between April - September 2019. The data consist ofserotonin levels, MoCA-Ina questionnaire, Hamilton Depression Rating scale (HDRS) score and Score Hamilton Anxiety Rating scale (HAM-A). Statistical analysis with fisher’s exact. Results: The data were obtained from 38 subjects which consisted of female (78.9%) and male (21.1%). There was a significant relationship between anxiety and cognitive function in CTTH. There was no significant relationship between depression and cognitive function on CTTH. Impaired cognitive function in CTTH is related to memory (90%) and executive domains (70%) in most cases. Discussion: There was no significant difference between normal and abnormal serum serotonin levels with impaired cognitive function. There was a significant association between low serum serotonin levels and anxiety in CTTH patients. There was no association between low serum serotonin levels and depression in CTTH patients. CTTH patients experienced cognitive impairments regarding memory and executive domains in most cases. Keywords: Chronic tension type headache, cognitive, MoCA-Ina, serotonin
Co-Authors Aprilia Aris Catur Bintoro Dani Rahmawati Dwi Pudjonarko Ega Primadona Endang Kustiowati EndangKustiowati Jimmy Eko Budi Hartono M.I. Widiastuti Trianggoro Budisulystio