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All Journal Indian Journal of Forensic Medicine & Toxicology
Noor Ghaleb Abdul Kareem
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Public Health

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Tissue Factor and Tissue Factor Pathway Inhibitor in Men and Women Affected with Hypertension Noor Ghaleb Abdul Kareem; Dakhel Ghani Omran
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16220

Abstract

Hypertension is one of the most common chronic diseases characterized with continuous elevation of bloodpressure. The present study involved tested 45 hypertensive men and 45 hypertensive women. Sixty (60)apparently healthy subjects (30 men and 30 women) were also included to serve as a control group. All menand women were subdivided into three groups according to their ages (41-50, 51-60, 61-70 years old).Results yield from present study indicated a significant decrease (p<0.05) in the levels of testosterone andestradiol in first age group of hypertensive men and women respectively and there were nonsignificantdifferences (p>0.05) in second and third age groups of patients compared to healthy groups.A significant progressive increase (p<0.05) in the levels of tissue factor (TF) in all groups of hypertensivemen and women compared to healthy groups. In contrast, values of tissue factor pathway inhibitor (TFPI)confirmed a significant lowering (p<0.05) in all age groups of hypertensive men and women when comparedwith those healthy subjects. In conclusion, data obtained from this study can be attributed to damage ofvascular system resulted from continuous increase blood pressure, drop of sexual hormones, and aging
Co-Authors Dakhel Ghani Omran