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All Journal METAMORFOSA Journal of Biological Sciences Jurnal Manajerial
Siti Masnunah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Environmental Science Immunology & microbiology

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OPTIMALISASI WAKTU PEKERJAAN PEMBANGUNAN PERUMAHAN GREEN HILL GRESIK MENGGUNAKAN METODE PERT DAN CPM Siti Masnunah
JURNAL MANAJERIAL Vol 4 No 1 (2017)
Publisher : Program Studi Manajemen Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.272 KB) | DOI: 10.30587/manajerial.v4i1.307

Abstract

This study aims to know the planning to control the project activities during the implementation phase. The success rate or failure of a project leads to less mature planning and less effective controls, resulting in project delays, increased implementation costs and lower quality. To set the time for completion of the project to be more effective and efficient can use PERT and CPM methods so as to reduce the impact of delays and swelling of implementation costs. The PERT (Program Evaluation and Review Technique) method is a method that aims to reduce as much as possible delays, Production, and coordinate various parts of a job thoroughly and accelerate the completion of the project. While the CPM method is a method of planning and control projects that have cost data in the past. Based on the analysis results show the initial duration of the project with duration of 180 days (6 months) with the total cost of Rp. 73.599253,59. As a result of overtime work system, the duration of its activities to be 164 days with project cost of Rp. 55,089,267.07.
Uji Efektivitas Neuroprotektif Ekstrak Daun Pepaya (Carica papaya L.) Terhadap Sel Piramidal Di Hipokampus Dan Korteks Serebri Mencit (Mus musculus L.) Yang Diinduksi Trimetiltin Siti Masnunah; Ngurah Intan Wiratmini; Ni Made Rai Suarni
Metamorfosa: Journal of Biological Sciences Vol 7 No 1 (2020)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2020.v07.i01.p05

Abstract

Penelitian ini bertujuan untuk mengetahui efek neuroprotektif ekstrak daun pepaya (Carica papaya L.) terhadap sel piramidal di hipokampus dan korteks serebri mencit (Mus musculus L.) yang diinduksi Trimetiltin serta untuk mengetahui dosis optimum ekstrak daun pepaya yang bersifat neuroprotektif. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan lima perlakuan yang terdiri dari K+ (hanya diinduksi TMT dosis 0,6 mg/kgBB), K- (hanya diberikan Na-CMC 0,5%), P1 (diinduksi TMT dan diberi ekstrak daun pepaya dosis 500 mg/kgBB), P2 (diinduksi TMT dan diberi ekstrak daun pepaya dosis 1000 mg/kgBB), P3 (diinduksi TMT dan diberi ekstrak daun pepaya dosis 2000 mg/kgBB). Parameter yang diamati adalah nekrosis sel piramidal dan persentase kerusakan sel piramidal pada hipokampus dan korteks serebri. Hasil penelitian menunjukkan terjadi penurunan persentase kerusakan sel piramidal di hipokampus pada P1 sebesar 26,46%, P2 sebesar 28,91%, dan P3 sebesar 26,67%. Persentase kerusakan sel piramidal di korteks serebri mengalami penurunan pada P1 sebesar 9,62%, P2 sebesar 11,14%, dan P3 sebesar 14,88%. Dosis optimum ekstrak daun pepaya yang bersifat neuroprotektif adalah dosis 2000 mg/kgBB (P3). Kata kunci: daun pepaya, TMT, neuroprotektif, nekrosis, hipokampus
Co-Authors Ngurah Intan Wiratmini Ni Made Rai Suarni