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All Journal Althea Medical Journal Jurnal Keperawatan Suaka Insan
Agustina Lestari
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Medicine & Pharmacology Nursing

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Predictor of Mortality in Acquired Immunodeficiency Syndrome Patients with Central Nervous System Opportunistic Infections Agustina Lestari; Sofiati Dian; Chrysanti Murad
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.685 KB)

Abstract

Background: Indonesia’s increase of acquired immunodeficiency syndrome (AIDS) cases is one of the fastest. Mortality cases of AIDS also increase per year. Central nervous system (CNS) opportunistic infection is one of the most likely manifestations on advanced stage of Human immunodeficiency virus (HIV)/AIDS patients. Common CNS opportunistic infections are toxoplasma infection and tuberculous meningitis (TBM). The study aimed to analyze the predictor of mortality in AIDS patients with CNS opportunistic infections.Methods: This study reviewed 151 medical records from AIDS patients with CNS opportunistic infection admitted to the Department of Neurology, Dr. Hasan Sadikin General Hospital Bandung from 2007-2012. This study was conducted from April to November 2013. Patients’ clinical manifestations (seizure, headache, altered consciousness), laboratory examination (CD4+ level count) and treatment history (antiretroviral or ART and cotrimoxazole) were collected. Chi-square and logistic regression test were used to determine the mortality predictor in patients.Results: Mortality rate was 37.7%. Clinical manifestations from patients were seizure 29.8%, altered consciousness 66.2%, and headache 88.7%. Patients had cotrimoxazole treatment 44.4% and 38.4% patients had ART. CD4+ level count data from 86 patients were obtained, 94% had CD4+ level count ≤200. Bivariate analysis showed altered consciousness had significant mortality predictor (Odd ratio (OR): 29.944; 95% Confidence interval (CI) 6.9–129.945; p<0,0). Multivariate analysis showed ART had highest predictive mortality value (OR: 2.968; 95% CI 1.236–7.126; p=0.015).Conclusions: Altered consciousness and no antiretroviral treatment are mortality predictors in AIDS patients with CNS opportunistic infections. [AMJ.2016;3(4):577–82] DOI: 10.15850/amj.v3n4.942
STUDY FENOMENOLOGI: PSIKOLOGIS PASIEN KANKER YANG MENJALANI KEMOTERAPI Agustina Lestari; Yuliani Budiyarti; Bahrul Ilmi
JURNAL KEPERAWATAN SUAKA INSAN (JKSI) Vol 5 No 1 (2020): Jurnal Keperawatan Suaka Insan (JKSI)
Publisher : STIKES Suaka Insan Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51143/jksi.v5i1.196

Abstract

Latar Belakang: Kanker merupakan penyebab kematian terbanyak terutama di negara berkembang. Penatalaksanaan untuk kanker ada beberapa macam yaitu melalui pembedahan, radioterapi dan kemoterapi. Kemoterapi memiliki dampak dalam berbagai aspek kehidupan antara lain dampak terhadap fisik dan psikologis. Seringkali perawatan pada pasien kanker hanya terfokus pada kondisi fisik saja sedangkan kondisi psikologis terabaikan. Terganggunya kondisi psikologis akan berpengaruh terhadap semakin memburuknya kondisi kesehatan pasien kanker. Tujuan: Untuk mengekplorasi aspek psikologis pasien kanker yang menjalani kemoterapi. Metode: Desain penelitian di rancang menggunakan metode kualitatif dengan pendekatan fenomenologi dimana pengumpulan data dengan melakukan wawancara mendalam (indept interview). Partisipan yang digunakan sebanyak 8 orang yaitu pasien kanker yang menjalani kemoterapi. Hasil:Penelitian menemukan 9 tema yaitu (1) respon psikologis pasien saat terdiagnosa kanker, (2) proses pengambilan keputusan pengobatan pada pasien kanker, (3) faktor yang mempengaruhi proses pengambilan keputusan pengobatan, (4) respon psikologis pasien kanker selama menjalani kemoterapi, (5) dampak yang dialami pasien kanker selama menjalani kemoterapi, (6) upaya dalam menghadapi dampak yang dialami selama menjalani kemoterapi, (7) keyakinan terhadap keberhasilan pengobatan, (8) perubahan yang dirasakan selama menjalani kemoterapi, (9) harapan selama menjalani pengobatan kemoterapi.
Co-Authors Bahrul Ilmi Chrysanti Murad Sofiati Dian Yuliani Budiyarti