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Chrysanti Murad
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Medicine & Pharmacology

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Predictor of Mortality in Acquired Immunodeficiency Syndrome Patients with Central Nervous System Opportunistic Infections Agustina Lestari; Sofiati Dian; Chrysanti Murad
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Indonesia’s increase of acquired immunodeficiency syndrome (AIDS) cases is one of the fastest. Mortality cases of AIDS also increase per year. Central nervous system (CNS) opportunistic infection is one of the most likely manifestations on advanced stage of Human immunodeficiency virus (HIV)/AIDS patients. Common CNS opportunistic infections are toxoplasma infection and tuberculous meningitis (TBM). The study aimed to analyze the predictor of mortality in AIDS patients with CNS opportunistic infections.Methods: This study reviewed 151 medical records from AIDS patients with CNS opportunistic infection admitted to the Department of Neurology, Dr. Hasan Sadikin General Hospital Bandung from 2007-2012. This study was conducted from April to November 2013. Patients’ clinical manifestations (seizure, headache, altered consciousness), laboratory examination (CD4+ level count) and treatment history (antiretroviral or ART and cotrimoxazole) were collected. Chi-square and logistic regression test were used to determine the mortality predictor in patients.Results: Mortality rate was 37.7%. Clinical manifestations from patients were seizure 29.8%, altered consciousness 66.2%, and headache 88.7%. Patients had cotrimoxazole treatment 44.4% and 38.4% patients had ART. CD4+ level count data from 86 patients were obtained, 94% had CD4+ level count ≤200. Bivariate analysis showed altered consciousness had significant mortality predictor (Odd ratio (OR): 29.944; 95% Confidence interval (CI) 6.9–129.945; p<0,0). Multivariate analysis showed ART had highest predictive mortality value (OR: 2.968; 95% CI 1.236–7.126; p=0.015).Conclusions: Altered consciousness and no antiretroviral treatment are mortality predictors in AIDS patients with CNS opportunistic infections. [AMJ.2016;3(4):577–82] DOI: 10.15850/amj.v3n4.942
Health Belief Model Theory Application on Voluntary Counseling and Testing among Homosexual Men in Bandung Greater Area Argya Nareswara; Chrysanti Murad; Irvan Afriandi
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: The number of human immunodeficiency virus (HIV) cases is high and is constantly increasing. Homosexual men as a transmission niche is not only significant in terms of numbers, but also in natural aspects of anal sex, tropism of HIV-1, and high-risk behavior. Voluntary Counseling and Testing (VCT) is important for accelerating diagnosis and management plan; yet the uptake on high-risk population in Indonesia is low. A behavior-reasoning theory, Health Belief Model (HBM), attempts to explain whether or not individuals engage in certain health behavior. This study tries to assess participation rate of VCT, to portray HBM variables perception, and to depict significance of HBM variables towards VCT uptake or VCT intention. Methods: This study was conducted in October-November 2014 using cross-sectional design; 127 respondents were gathered according to Respondent Driven Snowball Sampling. This study used an internet-based questionnaire derived from Champion’s 1984 mammogram HBM questionnaire. Privacy and compensation were obtained. The Chi square test and logistic regression of HBM variables were done. Results: The VCT uptake was low (15.7%). Certain sexual experience and commitment were significant (Commitment to Men p=0.027, Oral Sex experience with men p=0.001, Anal Sex Experience with men p=0.038). Chi Square test revealed significance on Perceived Susceptibility, Perceived Benefit, and Cues to Action. Conclusions: Uptake of VCT is considerably low compared with total high risk population and other similar studies. Personal Susceptibility to HIV/AIDS is recommended to be emphasized; while VCT Benefit and Cues to Action in young homosexual men communities are better encouraged. [AMJ.2016;3(4):595–604]DOI: 10.15850/amj.v3n4.945
Nurses’ Knowledge of Blood Culture Sampling Procedure Wulan Ardhana Iswari; Chrysanti Murad; Ida Parwati
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: False-positive blood culture results due to contaminated samples have shown to increasepatients’ health costs, including the use of broad spectrum antibiotics and prolonged hospital length ofstay. While previous research have suggested that increasing staff knowledge on proper specimen collectionlowers contamination rates significantly, staff’s current knowledge of hospital-recommended samplecollection procedure have yet to be assessed in Dr. Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.Methods: This was a cross-sectional descriptive study on 81 Emergency Department nurses in Dr. HasanSadikin General Hospital, Indonesia. Subjects were asked to complete a questionnaire in order to measuretheir knowledge of blood culture sampling procedure in accordance with the hospital’s standard operatingprocedure.Results: Among 81 subjects enrolled, 51 managed to adequately describe the prerequisites in proper bloodculture sampling procedure and their purpose as dictated by Dr. Hasan Sadikin General Hospital’s standardoperating procedure.Conclusions: Up to 67% of nurses conducting blood sampling procedure in Dr. Hasan Sadikin GeneralHospital’s Emergency Department understood the prerequisites of hospital-recommended blood culturesampling procedure and their purpose.
Co-Authors Agustina Lestari Argya Nareswara Ida Parwati Irvan Afriandi Sofiati Dian Wulan Ardhana Iswari