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All Journal MEDIA KONSERVASI AGRIVITA, Journal of Agricultural Science Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Natural
Rohmat Mujahid
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Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Education Energy Immunology & microbiology Medicine & Pharmacology Neuroscience Physics

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 1 
Conservation Status of Medicinal Plants from Papua and West Papua Province (Indonesia) Anshary Maruzy; Rohmat Mujahid
Media Konservasi Vol 24 No 2 (2019): Media Konservasi Vol. 24 No. 2 Agustus 2019
Publisher : Department of Forest Resources Conservation and Ecotourism - IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (550.465 KB) | DOI: 10.29244/medkon.24.2.114-123

Abstract

Research on Medicinal Plants and Jamu (RISTOJA) in of Papua and West Papua  provinces was conducted in November-December 2012 and May 2017 using the purposive sampling and snowball method. The purpose of the review in this paper is to find out the patterns and trends in species used, and to discuss the factors that cause the vulnerability of declining plant species due to harvest pressure. In this paper, RISTOJA’s  data is primary data and a review of the data is carried out by searching literature online and offline. From the results of RISTOJA in Papua and West Papua (Western New Guinea) in 2012 and 2017, there were 2929 numbers of medicinal plants, and it is estimated that from the 2929 numbers there were 983 species of medicinal plants, and from the estimated 983 species of medicinal plants there were 444 species of medicinal plants not yet identified, because most species do not have generative parts and there are 529 medicinal plants identified to species level (2.1% of the total flora of Papua and West Papua). From these data, one species of medicinal plants was included in the category of Critically Endangered (0.19%), two species of Endangered (0.38%), and four species of Vulnerable (0.76%), two species Near Threatened (0.38%), 61 species of Least Concern (11.53%), six species of Data Deficient (DD). Threatened status is more commonly found in species recorded as harvested by traditional healer not from gardens (forests and others). Thus, the continuous exploitation of harvests from the forest and the wildlife can lead to an increase in the future Red List status of some species which are at risk threatened condition. Keywords: IUCN, medicinal plants, Papua, RISTOJA, Western Papua  
Kaempferia galanga L. A Medicinal Plant Used By Indonesian Ethnic Groups: Genetic Diversity Based on Inter-Simple Sequence Repeats (ISSR) Dyah Subositi; Nina Kurnianingrum; Rohmat Mujahid; Yuli Widiyastuti
AGRIVITA, Journal of Agricultural Science Vol 42, No 1 (2020)
Publisher : Faculty of Agriculture University of Brawijaya in collaboration with PERAGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17503/agrivita.v42i1.1850

Abstract

Kencur (Kaempferia galanga L.) has been recognized as a medicinal plant used by many ethnic groups in Indonesia. Up to present time, information on the diversity of the respected plant is still limited. The aim of this research was to reveal the genetic diversity of K. galanga in Indonesia as a baseline medicinal plant database. Inter-Simple Sequence Repeat (ISSR) molecular markers were employed to analyze the genetic diversity information of K. galanga from 12 selected locations in Indonesia where ethnic groups used the plant. Dice index similarity was used to calculate a similarity index, and Unweighted Pair Group Method Using Arithmetic Mean (UPGMA) was used to constructing a dendrogram. Ten selected ISSR primers generated 104 amplified DNA fragments, of which 98 fragments (94.2%) were polymorphic. The genetic similarity index among accessions ranged from 49.6–93.3%, indicating a high level of genetic diversity in K. galanga. The ISSR markers were thus able to genetically differentiate K. galanga accessions.
UJI KLINIK RAMUAN JAMU IMUNOSTIMULAN TERHADAP FUNGSI GINJAL DAN FUNGSI HATI Sunu Pamadyo; Rohmat Mujahid
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.687 KB) | DOI: 10.31942/jiffk.v0i0.1195

Abstract

ABSTRAK   Kunyit, temulawak dan temu mangga adalah tanaman obat yang secara terpisah atau digabung biasa digunakan masyarakat untuk meningkatkan daya tahan tubuh, mengurangi pegel linu dan menambah stamina.Diharapkan gabungan dari ketiga tanaman ini dapat meningkatkan efektifitasnya sebagai immunostimulan (meningkatkan daya tahan tubuh) sehingga perlu dilakukan penelitian pada manusia dengan gangguan status immunologi.Tuberkulosis paru (TBC) merupakan salah satu penyakit infeksi kronis yang mengganggu sistem imun penderitanya, maka penelitian ini menggunakan penderita TBC dalam jumlah terbatas. Penelitian ini dilakukan di 3 tempat yaitu di Puskesmas Tawangmangu, Puskesmas Karangpandan dan Klinik Saintifikasi Jamu Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional dengan jumlah subyek sebanyak 32 orang. Subyek adalah penderita TBC yang masih menjalankan program pengobatan TBC metode DOTS, dan selama penelitian subyek diharuskan tetap melaksanakan pengobatan TBC tersebut. Subyek dibagi menjadi 2 kelompok yaitu kelompok uji dan kelompok kontrol. Semua kelompok tetap diharuskan melanjutkan pengobatan TBC, namun kelompok uji diberikan bahan uji jamu immunostimulan sedangkan kelompok kontrol tidak diberikan bahan uji.Semua subyek dinilai kadar IFN g, hematologi lengkap serta fungsi hati dan fungsi ginjal untuk memantau keamanan. Hasil penelitian terhadap keamanan jamu secara subyektif tidak ditemukan keluhan tambahan, tidak ada tanda-tanda keracunan akut, dan secara laboratoris tidak ada perubahan bermakna nilai-nilai hematologi rutin, fungsi hati dan fungsi ginjal. Hal ini berarti menandakan bahwa ramuan jamu untuk immunostimulan aman digunakan. Kata kunci : jamu, immunostimulan, keamanan, fungsi hati, ginjal
ANTIOXIDANT ACTIVITY OF N-HEXANE EXTRACT OF NUTMEG PLANTS FROM SOUTH ACEH PROVINCE Binawati Ginting; Mustanir Mustanir; Hira Helwati; Lydia Septa Desiyana; Eralisa Eralisa; Rohmat Mujahid
Jurnal Natural Volume 17, Number 1, March 2017
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.588 KB) | DOI: 10.24815/jn.v17i1.6969

Abstract

Abstract. It has tested the antioxidant activity of n-hexane extract respective roots, bark, fruit and seed crops of nutmeg against DPPH. Each extracted by maceration method with n-hexane. The extraction of each plant nutmeg with n-hexane extract obtained yield of n-hexane respectively 8,35%; 81,5%; 11,89% and 55,63%. The result of the antioxidant activity of n-hexane extract of each plant nutmeg against DPPH with a concentration of 25 ppm, 50 ppm and 100 ppm is obtained IC50, respectively, are 0,216 ppm, 63,755 ppm, 43,998 ppm and 11,599 ppm and positive control vitamin C ( IC50 = 3,657 ppm). Vitamin C is a standard compound is more often used than butyl for very high antioxidant activity. The antioxidant activity increases from high to low at the roots, seeds, fruits and bark of plants nutmeg in a row. Based on data GC-MS chemical components of each successive extracts of roots, bark, fruit and seeds are 41, 41, 44, 43 components of secondary metabolites. The main components of each part of the plant based on data from GC-MS are a 5-Octadecanoic acid, linalool, eugenol, myristicin, methoxyeugenol. The compounds are thought to play an active role in inhibiting free radicals from DPPH. n-Hexane extract nutmeg plant potential as an antioxidant. Keywords:Nutmeg (Myristica fragrans Houtt), n-hexane extract, Antioxidant, DPPH
ANTIOXIDANT ACTIVITY OF N-HEXANE EXTRACT OF NUTMEG PLANTS FROM SOUTH ACEH PROVINCE Binawati Ginting; Mustanir Mustanir; Hira Helwati; Lydia Septa Desiyana; Eralisa Eralisa; Rohmat Mujahid
Jurnal Natural Volume 17, Number 1, March 2017
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v17i1.6969

Abstract

Abstract. It has tested the antioxidant activity of n-hexane extract respective roots, bark, fruit and seed crops of nutmeg against DPPH. Each extracted by maceration method with n-hexane. The extraction of each plant nutmeg with n-hexane extract obtained yield of n-hexane respectively 8,35%; 81,5%; 11,89% and 55,63%. The result of the antioxidant activity of n-hexane extract of each plant nutmeg against DPPH with a concentration of 25 ppm, 50 ppm and 100 ppm is obtained IC50, respectively, are 0,216 ppm, 63,755 ppm, 43,998 ppm and 11,599 ppm and positive control vitamin C ( IC50 = 3,657 ppm). Vitamin C is a standard compound is more often used than butyl for very high antioxidant activity. The antioxidant activity increases from high to low at the roots, seeds, fruits and bark of plants nutmeg in a row. Based on data GC-MS chemical components of each successive extracts of roots, bark, fruit and seeds are 41, 41, 44, 43 components of secondary metabolites. The main components of each part of the plant based on data from GC-MS are a 5-Octadecanoic acid, linalool, eugenol, myristicin, methoxyeugenol. The compounds are thought to play an active role in inhibiting free radicals from DPPH. n-Hexane extract nutmeg plant potential as an antioxidant. Keywords:Nutmeg (Myristica fragrans Houtt), n-hexane extract, Antioxidant, DPPH
Co-Authors Anshary Maruzy Binawati Ginting Binawati Ginting Dyah Subositi Eralisa Eralisa Hira Helwati Lydia Septa Desiyana Mustanir Mustanir Nina Kurnianingrum Sunu Pamadyo Yuli Widiyastuti