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All Journal Jurnal Kesehatan Reproduksi Jurnal Penelitian Kesehatan Suara Forikes Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Kesehatan Reproduksi
Anak Agung Istri Dalem Cinthya Riris
Universitas Airlangga
Health Professions Medicine & Pharmacology Nursing Public Health

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Potensi Ekstrak Solanum betaceum sebagai Agen Protektif Sel Leydig pada Mencit yang Dipapar Timbal Asetat Anak Agung Istri Dalem Cinthya Riris; Reny I’tishom; Siti Khaerunnisa
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11 (2020): Nomor Khusus Mei-Juni 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11nk313

Abstract

Lead exposure as environmental pollution can cause male reproductive problems. Provision of natural antioxidants can be an alternative solution to protect male reproductive function. This research was conducted to investigate the potential of Solanum betaceum extract as a protective agent for Leydig cells in mice exposed to lead acetate. The entire research process with a replication unit of 40 male mice. Mice were divided into five groups with each treatment given orally. The negative control group (K0) only gets aquadest for 35 days, the positive control group (K1) gets aquadest day 1-3, day 4-35 get lead acetate at a dose of 0.075 mg/kg BW/day, the treatment group (P1), (P2 ), and (P3) only given Solanum betaceum extract at day 1-3 with sequential doses of 100 mg/ kg BW /day, 200 mg/ kg BW /day, and 400 mg/ kg BW /day, then 4-35 days were given Solanum extract betaceum and after 1 hour given lead acetate. The results of this study indicate that there were significant differences between groups with p
Role of antioxidant to protect Leydig cells induced by reactive oxygen species: a literature review Anak Agung Istri Dalem Cinthya Riris; Reny I'tishom; Siti Khaerunnisa
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.4693

Abstract

The Leydig cells play crucial role in steroidogenesis and spermatogenesis. Those processes need complex communication in hormonal and testicular to maintain male reproductive function. Abnormal condition induced by reactive oxygen species reduce cell viability through lipid peroxidation and apoptotic pathway. Antioxidant ameliorate ROS elevation and prevent cell damage. Specifically, Leydig cells are vulnerable to ROS exposure and decline its function in mediating spermatogenesis. Therefore, it is needed to improve Leydig cells viability within antioxidant supplementation. This study aimed to determine the protective effect of antioxidant on Leydig cells induced by reactive oxygen species. This type of study is a literature review. Various studies have been reviewed through critical appraisal tool Olsen-Baisch Scoring for integrated review. Furthermore, this study highlighted the importance of the mechanism of antioxidant as protective agent of Leydig cells. Supplementation of antioxidant with the correct administration, dosage, and duration is potential to balance reactive oxygen species level and protect Leydig cells.    Keywords             : Leydig cell, antioxidant, reactive oxygen species, infertility
EFFECTIVENESS OF PEER EDUCATION IN DECREASING ADOLESCENT PREGNANCY: A LITERATURE REVIEW Anak Agung Istri Dalem Cinthya Riris; Ni Kadek Diah Purnamayanti
Jurnal Kesehatan Reproduksi Vol 12 No 1 (2021): JURNAL KESEHATAN REPRODUKSI VOLUME 12 NOMOR 1 TAHUN 2021
Publisher : Puslitbang Upaya Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/kespro.v12i1.3831

Abstract

Background: Currently, the number of adolescents who have sexual intercourse is increasing and those make a higher risk of medical, psychological, and social implications. This behaviour is obviously leading to an increase the number of adolescence pregnancy. Sex education and counselling in many countries is delivered by health care professionals. In Indonesia, there are some sex education programs delivered by peer educators but their success in reducing adolescence pregnancy is unknown. Objective: The aim of this study was to analyze the effectiveness of a peer reproductive health education program in decreasing unplanned pregnancy in adolescents. Method: This integrative literature review was based on 3 databases which included Google Scholar, Pubmed and SAGE Journal. The inclusion criteria were articles published within the 2012–2018-year range, written in English, and the entire article was available and accessible. Only original articles with experimental design will be included. The quality of the selected articles was defined by using the Olsen-Baisch Scoring critical appraisal tool for integrative review. Result: Peer education builds social support and sense of belonging. The content is not only about unplanned pregnancy but also STI and HIV; responsible decision making; and body image identification. Peer educator can be the role model and have greater opportunities to counter the risk of adolescent pregnancy. Conclusion: Preventing adolescent pregnancy can save the next generation and improve adolescent health. Peer educator as part of health provider connect adolescents with their reproductive health needs. This approach would be beneficial strategy consider by health provider to protect adolescents. Keywords: adolescent, peer educator, pregnancy, sex education
EFFECTIVENESS OF PEER EDUCATION IN DECREASING ADOLESCENT PREGNANCY: A LITERATURE REVIEW Anak Agung Istri Dalem Cinthya Riris; Ni Kadek Diah Purnamayanti
JURNAL KESEHATAN REPRODUKSI Vol 12 No 1 (2021): JURNAL KESEHATAN REPRODUKSI VOLUME 12 NOMOR 1 TAHUN 2021
Publisher : IAKMI South Tangerang Branch

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58185/jkr.v12i1.5

Abstract

Abstract Background: Currently, the number of adolescents who have sexual intercourse is increasing and those make a higher risk of medical, psychological, and social implications. This behaviour is obviously leading to an increase the number of adolescence pregnancy. Sex education and counselling in many countries is delivered by health care professionals. In Indonesia, there are some sex education programs delivered by peer educators but their success in reducing adolescence pregnancy is unknown. Objective: The aim of this study was to analyze the effectiveness of a peer reproductive health education program in decreasing unplanned pregnancy in adolescents. Method: This integrative literature review was based on 3 databases which included Google Scholar, Pubmed and SAGE Journal. The inclusion criteria were articles published within the 2012–2018-year range, written in English, and the entire article was available and accessible. Only original articles with experimental design will be included. The quality of the selected articles was defined by using the Olsen-Baisch Scoring critical appraisal tool for integrative review. Result: Peer education builds social support and sense of belonging. The content is not only about unplanned pregnancy but also STI and HIV; responsible decision making; and body image identification. Peer educator can be the role model and have greater opportunities to counter the risk of adolescent pregnancy. Conclusion: Preventing adolescent pregnancy can save the next generation and improve adolescent health. Peer educator as part of health provider connect adolescents with their reproductive health needs. This approach would be beneficial strategy consider by health provider to protect adolescents. Keywords: adolescent, peer educator, pregnancy, sex education
Co-Authors I'tishom, Reny Ni Kadek Diah Purnamayanti Siti Khaerunnisa