This Author published in this journals
All Journal Health Notions
Kuntoro Kuntoro
Faculty of Public Health, Airlangga University

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Multivariate Adaptive Regression Spline Approach for the Classification Accuracy of Drugs User in East Java Stefanny Zulistya Wenno; Kuntoro Kuntoro; Soenarnatalina Soenarnatalina
Health Notions Vol 1, No 2 (2017): April-June
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (79.444 KB) | DOI: 10.33846/hn.v1i2.18

Abstract

Background: Classification method is a statistical method for grouping or classifying the systematically arranged data into a group so we can know that an individual are in a particular group. Multivariate Adaptive Regression Spline (MARS) introduced by (Friedman, 1991) is a methodology for approximating functions of many input variables given the value of the function at a collection of points in the input space. Although training times for this method tend to be much faster than feed forward neural networks using back propagation, it can still be fairly slow for large problems that require complex approximations (many units). Methods: This was a nonreactive study, which is a measurement which individuals surveyed did not realize that they are part of a study. Result: Based on the best model selection criteria MARS then the selected is with model BF 20, MI 1 and MO 0 with the form Y = 0.929944 + 0.912438 * BF1 - 0.218729 * BF2 + 0.886429 * BF3 + 0.215575 * BF4 + 0.0745423 * BF5 - 0.232014 * BF6 + 0.0472966 * BF7 - 0.0367996 * BF8 + 0.0188678 * BF9 + 0.0304537 * BF11. Accuracy of drugs user rehabilitation classification that non relapse and relapse status based on MARS model is calculated using precision classification value. The accuracy level of drugs user rehabilitation classification in East Java using MARS method produces accuracy of 95,71% and misclassification of 4,29%. The magnitude of the above classification accuracy is due to the large prediction in the nonrelapse class that as many as 269 people with nonrelapse status are appropriately predicted in the nonrelapse status class. Conclusion: There are four important variables included in the best MARS model that is age of first use of drugs, how to use drugs, marital status and jobs. The accuracy level of drugs user rehabilitation classification in East Java using MARS method produces accuracy of 95,71% and misclassification of 4,29%. Keywords: Multivariate adaptive regression spline, Classification accuracy, Drugs user.
Expression of VCAM in Male Wistar Rats (Rattus norvegicus) with Hypercholesterolemia Supplemented with Pumpkin Seeds (Cucurbita moschata Duch) Extract Jujuk Proboningsih; Bambang Wirjatmadi; Kuntoro Kuntoro; Merryana Adriani
Health Notions Vol 2, No 6 (2018): June
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (970.221 KB) | DOI: 10.33846/hn.v2i6.214

Abstract

Treatment of cardiovascular diseases tends to be expensive and requires long-term therapy. Investigation about the effect of pumpkin seeds on prevention of endothelial dysfunction of blood vessel has never been reported yet, accordingly, bodies of research are required to know its effectiveness. This study aimed to analyze the expression of Vascular Cell Adhesion Molecule (VCAM) in male Wistar rats (Rattus norvegicus) with hypercholesterolemia supplemented with pumpkin seeds extract (Cucurbita moschata Duch). This was an experimental laboratory study with randomized post-test control group design. The independent variable was pumpkin seeds extract, and the dependent one was expression of VCAM. Data analysis employed chi-square test to test the difference between control and treatment groups. Study results showed that there was significant difference (p=0.000) between VCAM expression in group-K2 (positive control) as compared to group-K1 (negative control) and group-K5 (treatment group-dose 3) α=0.001, whereas no significant difference was found between that of as compared to group-K3 (treatment group-dose 1) α=0.125 and group-K4 (treatment group-dose 2) α=0.05. The study showed reduction of VCAM expression in treatment groups consisted of male Wistar rats with hypercholesterolemia supplemented with pumpkin seeds (Cucurbita moschata Duch) extract. Keywords: Pumpkin seeds, VCAM expression, hypercholesterolemia