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All Journal Jurnal Florea Jurnal Farmasi Sains dan Komunitas Jurnal Biodjati Jurnal Abdimas Berdaya : Jurnal Pembelajaran, Pemberdayaan dan Pengabdian Masyarakat Eastasouth Journal of Effective Community Services
Siti Nur Azizah
Akademi Farmasi Jember
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Journal : Jurnal Florea

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Pengaruh Variasi Suhu Sebelum dan Setelah Penyimpanan terhadap Stabilitas Fisik dan Kontaminasi Bakteri Suspensi Antasida Generik Rica Laily Istighfarin; Siti Nur Azizah; Asa Falahi; Amaliyah Nurul Hidayah
Florea : Jurnal Biologi dan Pembelajarannya Vol 9, No 2 (2022)
Publisher : UNIVERSITAS PGRI MADIUN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/florea.v9i2.11904

Abstract

The purpose of this study was to determine the effect of temperature variations before and after storage on physical stability and bacterial contamination of the antacid suspension. The samples in this study were generic antacid suspensions with variations in storage temperature stored at 15-30°C (room), 2-8°C (cold), and 30-40°C (warm). Physical evaluations were carried out in the form of organoleptic tests, pH tests, viscosity tests and there was a bacterial contamination test. The results of the organoleptic test showed that the generic antacid suspension before and after storage had no change in smell, color and taste. The pH test has a stable pH and meets the requirements, namely pH between 7.3 and 8.5, the statistical test results obtained were 0.589> 0.05, which means that the pH before and after storage there was no significant difference. The viscosity test met the requirements, namely viscosity from 0.37 to 3.9 dpas. statistical test results obtained 0.023 <0.05, which means that the viscosity before and after storage there was a significant difference. The results of the Total Plate Number test before storage there was no contamination with ALTB values, namely 1.3x101 colonies/ml, 1,3x101 colonies/ml, and 1x101 colonies/ml, based on The International Pharmacopeia-7th edition the requirement for suspension bacterial contamination ≤ 1x102 colonies/ml, the result showed that contamination happened in all samples after storage. It can be concluded that bacterial contaminatios occured in all samples with temperature variations before and after storage but not affected on physical stability of antacid suspension.
POTENSI MEDIA AGAR PISANG MAS SEBAGAI MEDIA TUMBUH Staphylococcus aureus DAN Aspergillus niger Amaliyah Nurul Hidayah; Ayuk Lestari; Mikhania Christiningtyas Eryani; Siti Nur Azizah
Florea : Jurnal Biologi dan Pembelajarannya Vol 9, No 2 (2022)
Publisher : UNIVERSITAS PGRI MADIUN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/florea.v9i2.14237

Abstract

The high cost of instant culture media on the market has become the background of research to develop Mas banana (Musa acuminata Colla) Agar as a culture medium for Staphylococcus aureus and Aspergillus niger. Culture media is a mixture of nutrients or food substances needed by microorganisms for their growth. The purpose of this study was to determine the potential of Mas banana Agar (Musa acuminata Colla) at various concentrations of 2%, 4%, 6%, and 8% on the number of Staphylococcus aureus colony and Aspergillus niger micellium diameter. The type of research used was experimental research. The research stages were making Mas banana flour, prepared suspension of Staphylococcus aureus and Aspergillus niger, prepared Mas banana Agar, bacterial culture (spread method) incubated for 24hours at 37°C and mold (dot method) were incubated for 7 days at 37°C. Based on the results, S. aureus colonies on Mas banana Agar at 2%, 4%, 6% and 8% were 43.67 colonies, 52 colonies, 17.33 colonies and 7.67 colonies respectively. The average of Aspergillus niger mycelium diameter at 2%, 4%, 6% and 8% were 11.43 mm, 12.63 mm, 25.26 mm and 62.33 mm respectively. It can be concluded that Staphylococcus aureus and Aspergillus niger cultures growth on Mas banana Agar (Musa acuminata Colla) at various concentrations of 2%, 4%, 6%, 8%.
Co-Authors Asa Falahi Ayuk Lestari Azizah Azizah Denok Risky Ayu Paramita Dewi Rashati Diyan Ajeng Rossetyowati Dyan Maulani Eryani, Mikhania Christiningtyas Hadi Barru Hakam Fajar Siddiq Rica Laily Istighfarin rosida hari