Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kefarmasian Indonesia Jurnal Insan Farmasi Indonesia
Alvi Kusuma Wardani
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
UJI AKTIVITAS ANTIKOLESTEROL HASIL FERMENTASI ANGKAK PADA TIKUS GALUR Sprague dawley Abdul Rahman Wahid; Armiyatin Damayanti; Alvi Kusuma Wardani
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.296

Abstract

Hypercholesterolemia is a condition in which the levels of cholesterol in the blood increases and decreases in HDL cholesterol levels below the normal range. Low levels of HDL cholesterol and high levels of LDL cholesterol can increase the risk of atherosclerosis. Angkak is a fermented product from brown rice using mold Monascus purpureus. Angkak contains secondary lovastatin which functions as an anti-cholesterol. This study aims to determine the effect of the administration of brown rice Angkak to decreasing LDL levels at a dose of 15 mg/200gBB, 40 mg/200gBB, and 65 mg/200gBB in mice induced by high cholesterol feed. This type of research is true experimental laboratory withmethods pre and post test control group design. The results showed that Angkak dosages of 15 mg / 200gBB, 40 mg / 200gBB, and 65 mg / 200gBB were able to reduce levels in rats induced high cholesterol. The conclusion of this study is that red rice Angkak containing lovastatin has an anticolesterol effect on decreasing total cholesterol, LDL, and trigliseride levels in rats.
Uji Aktivitas Antimalaria in vitro dari Ekstrak Etanol Batang Tanaman Ashitaba (Angelica keiskei [Miq.] Koidz) Alvi Kusuma Wardani; Abdul Rahman Wahid; Yanti Astuti
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.815

Abstract

Malaria infection is still become a serious and complex health problem in the world. The diffi culty in treating malaria is caused by the resistance of the malaria parasite to synthetic drugs. One alternative to prevent resistance is to use herbal medicines such as the Ashitaba plant (Angelica keiskei [Miq.] Koidz). This study aims to determine the activity of Ashitaba stem ethanol extract as an antimalarial to the Plasmodium falciparum parasite strain 3D7. Ashitaba stem extract was tested for chemical compound content and antimalarial activity against Plasmodium falciparum strain 3D7 with concentrations of 100, 10, 1, 0.1 and 0.01 μg / ml. The test results for the chemical compounds of Ashitaba stem extract were positive for fl avonoids and chalcone compounds. Ashitaba stem extract with a concentration of 100, 10, 1, 0.1 and 0.01 μg / ml had an average resistance value of 67.75%, 46.61%, 32.56%, 19.60%, and 7.56%. The antimalarial activity test results of Ashitaba stem ethanol extract had an IC50 value of 11.07 μg / ml. The antimalarial activity of Ashitaba stem ethanol extract is included in the category of good antimalarial activity because the IC50 value falls within the range of 10-50 μg / ml.
Co-Authors Abdul Rahman Wahid Armiyatin Damayanti Yanti Astuti