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All Journal Jurnal Serambi Engineering Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Insan Farmasi Indonesia
Novriyanti Lubis
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health

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STUDI IN SILICO SENYAWA YANG TERKANDUNG DI DALAM RIMPANG TEMULAWAK (Curcuma xanthorriza Roxb.) SEBAGAI ANTIHEPATITIS B Riska Prasetiawati; Shielva Meilanda; Benny Permana; Novriyanti Lubis
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.788

Abstract

Hepatitis B is inflammation of the liver caused by the Hepatitis B virus (HBV). HBV is a DNA virus that plays a role in virus replication through the process of reverse transcription. The curcuma rhizome against HBV reseptor with protein ID 1A7L and ID 1IUD using the Autodock Tools program. The 1A7L receptor showed that the curcumin compound had ?G of -8.05 kcal/mol and the value of inhibition constant (KI) of 1.26 µM, natural ligands had ?G of -8.17 kcal/mol and the value of KI was 1.03 µM, and Lamivudin as a comparative ligand had ?G of -7.02 kcal/mol and the value of the KI was 7.13 µM, while the result of the 1IUD receptor had ?G of -8.44 kcal/mol and KI value of 647.75 nM, natural ligand had ?G of -6.90 kcal/mol and KI value of 8.78 µM, and Lamivudin as a comparative ligand had ?G of -5.01 kcal/mol and the value of the KI was 211.47 nM. The absorption and distribution prediction results showed the curcumin compound had a Caco2 value of 20.07 nm sec-1, the percentage of HIA was 94.40% and plasma Binding Protein was 88.03%. The curcumin compound fulfills all Lipinski's is non-mutagenic and carcinogenic negative.
Enkapsulasi Probiotik Lactobacillus sp. Menggunakan Biopolimer Alginat dan Kitosan dengan Metode Satu Tahap Tazkia Nur Hidayah; Djaenudin Djaenudin; Novriyanti Lubis
Jurnal Serambi Engineering Vol 6, No 2: April 2021
Publisher : Fakultas Teknik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jse.v6i2.2881

Abstract

Lactobacillus sp are gram-positive bacteria that cannot survive in acidic conditions, such as stomach acid conditions (pH 1.5- pH 2.5) so that a carrier is needed so that Lactobacillus sp can survive when colonizing the intestine. One way to protect Lactobacillus sp in acidic conditions is by encapsulation. The core material used for Lactobacillus encapsulation uses a mixture of Na-alginate and chitosan. The mixture formed then becomes microcapsules using an electrospinning device. One of the components of the electrospinning device is a syringe that provides pressure to form droplets that fall into a solution of CaCl2 and chitosan with a concentration of 1.2%; 1.6% and 2%. Lactobacillus sp. The encapsulated viability was tested for viability in simulated gastric acid (0.2% NaCl pH 1.2 and pH 3) for 1 minute, 60 minutes, and 120 minutes using the Total Plate Count (TPC) method. After the viability test was carried out, it was found that Lactobacillus sp. encapsulation results with a 2% chitosan matrix with the number of colonies in the simulated gastric acid pH 3 for 1 minute is 4x109 cfu / g, for 60 minutes 3x109 cfu / g and for 120 minutes is 1x9 cfu /g.
Penyuluhan Kesehatan Lingkungan di SDN 2 Kersamenak Kecamatan Tarogong Kidul Kabupaten Garut Novriyanti Lubis; Muhammad Fairuzzaman; Mike Agusti Nuryani; Bentang Yasha Muhammad Murki; Sri Putriany; Najwa Najiyya Arsyisyifa; Aprilia Sakinah; Rai Nurhalizah
ABDI: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 5 No 4 (2023): Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Labor Jurusan Sosiologi, Fakultas Ilmu Sosial, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/abdi.v5i4.523

Abstract

Early introduction of education about environmental health, especially for elementary school children, is very important. This is because schoolchildren are one of the groups most vulnerable to health problems. This counseling aims to increase the awareness of students at SDN 2 Kersamenak on environmental health. The socialization activity was carried out by providing counseling through media flayers and education in the form of environmental health materials directly to students at SDN 2 Kersamenak. Analysis of the level of students' understanding was identified through a survey method using 10 multiple choice test items based on three factors, namely understanding the definition and benefits of environmental health, and understanding of the characteristics of a good environment. In this school total 82 students, while only 42 students filled out the questionnaire. The survey results showed that 97.6% of students already understood the importance of environmental health even before the counseling was carried out. However, this socialization activity can also be said to be successful, because there is an increase in the percentage of knowledge of SDN 2 Kersamenak students about environmental health.
Co-Authors Aprilia Sakinah Benny Permana Bentang Yasha Muhammad Murki Djaenudin Djaenudin Mike Agusti Nuryani Muhammad Fairuzzaman Najwa Najiyya Arsyisyifa Rai Nurhalizah Riska Prasetiawati Shielva Meilanda Sri Putriany Tazkia Nur Hidayah