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Formulasi Pembuatan Sabun Padat Anti Acne Ekstrak Etanol Kulit Pisang Kepok (Musa Balbisiana Colla) Nur Azizah Syahrana; Indah Indah; Suryanita Suryanita; Muhammad Asri SR
Journal of Pharmaceutical and Health Research Vol 3 No 3 (2022): October 2022
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v3i3.2838

Abstract

Herbal soap is a natural soap that can be made from plant extracs. Kepok banana pee (Musa balbiasana colla) as one of the plants that contains high antioxidants is in line with the research objective, namely evaluating the formulation of anti acne solid soap making of kepok banana ethanol extract. This type of research is a laboratory experiment, namely making solid soap from yellow kepok banana peels (Musa balbisiana colla) which is chopped then dried and mashed using a blender then extracted using 70% ethanol and formulated into solid soap preparetions with variations in the concentration of yellow kepok banana extrac FII (10%) and FIII (15%) did not meet the good physical quality for organoleptic testing and 3 people experienced irritation, while FI(5%) met all requirements for good physical quality seen from the organoleptic test, pH 8 test (8-11), the foam strength tes was 6 cm (60mm) and none of the respondents experienced skin irritation. So it can be formulated into solid soap preparations with the best concentration using extract 5%.
The Effect of Squid (Loligo sp.) Bone Chitosan Powder on Total Cholesterol Levels of Rats (Rattus norvegicus) Indah Indah; Muhammad Asri; Suryanita Suryanita; Astika Irianti
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 21 No. 01 Juli 2024
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v0i0.15666

Abstract

Bones in squid (Loligo sp.) can be used as a source of medicinal ingredients, one of which is chitosan. The polymer in chitosan contains amino and hydroxyl groups per residue, giving chitosan many biological activities, such as anti-inflammatory, antimicrobial, hypoglycemic, hypocholesterolemic, and immunostimulatory effects. This study aims to determine the antioxidant activity and the effect of chitosan squid bone powder on the total cholesterol levels of rats (Rattus norvegicus). This type of research used an experimental method with a one-group pre-test and post-test design, in which 12 male white rats, body weight 150 g, were divided into four groups. Group 1 was a negative control of 1% Na-CMC, group II chitosan 50 mg/kg, group III chitosan 100 mg/kg, and group IV positive control of simvastatin 10 mg, which each group was given orally; the treatment was carried out for two weeks. The results showed a decrease in the mean after treatment in the treatment group with chitosan powder, but there was no significant difference compared to the control group (P>0.005). This shows that squid bone chitosan powder reduced total cholesterol levels in rats.