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All Journal As-syifaa Jurnal Farmasi
Zainal Abidin
Fakultas Farmasi, Universitas Muslim Indonesia, Makassar
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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PENGUJIAN AKTIVITAS EKSTRAK ETANOL KULIT BUAH KECOMBRANG (Etlingera elatior (Jack) R.M.Sm) SEBAGAI INHIBITOR TIROSINASE Harti Widiastuti; Zainal Abidin
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.769

Abstract

Healthy skin should have a flat surface, the texture is soft, elastic, and have the same skin color. Skin color is determined by the size, number and distribution of melanin pigment. Pigment brownish pigment melanin is to protect the skin from UV light scattering. An enzyme that plays a role in this browning reaction is tyrosinase. Based on this research is conducted on the fruit skin kecombrang to see the activity of the enzyme tyrosinase barriers and whether rind kecombrang can inhibit tyrosinase enzyme and with the aim to utilize natural materials and waste that can inhibit the enzyme tyrosinase and can be used as a skin whitheter. Research iniated by the extraction of fruit skins kecombrang using etanol. Flavonid content test on the sample using Mg powder and HCl p, the results show a color change from dark brown to yellow. So positive it contains flavonoids. Measurements were contucted on a maximum wavelength of 478,003 nm, using the substrate L-tyrosine and the enzyme tyrosinase. Using comparators hidroquinon. Of the results of this study concluded that kecombrang fruit peel ectract at a concentration of 2 mg/mL could inhibit amounted to 55,92% and a concentration of 2,5 mg/mL could inhibit amounted to 56,58%
Co-Authors Harti Widiastuti