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Muhammad Asri
Sekolah Tinggi Ilmu Kesehatan Mega Rezky Makassar
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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PENGARUH EFEK EKSTRAK ETANOL DAUN SIRIH ( Piper Betle Linn.) SEBAGAI ANTIOKSIDAN TERHADAP LUKA BAKAR PADA KULIT PUNGGUNG KELINCI (Oryctolagus Cuniculus) Muhammad Asri
As-Syifaa Jurnal Farmasi Vol 9, No 2 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.582 KB) | DOI: 10.33096/jifa.v9i2.302

Abstract

The burn are injuries to the skin where a response to the skin and subcutaneous tissue to the trauma experienced. The burn with partial thickness is a burn that does not damage the epithelial tissue of the skin and only damage some of the epithelial. This research aims to determine the effect of ethanol extract of betel leaf (Piper betle Linn.) As an antioxidant to burns on the skin back of the rabbit's (Oryctolagus Cuniculus). The experimental method was carried out experimentally, divided into 5 groups and treatment for 7 days, P1 negatife control (made wound on the skin back of rabbit and smeared with vaseline flavum), P2 positif control (made wound on rabbit’s skin back and smeared with bioplacenton ointment) P3 (made wound and ethanol extract of betel leaf with 5% concentration), P4 (made wound and ethanol extract of betel leaves with 10% concentration), P5 (made wound and ethanol extract of betel leaves with 15% concentration). The result of the research on the measurement of diameter of burn area on  rabbit's skin back before and after treatment, group I 2.5 cm and 2.4 cm, group II 2.5 cm and 1.9 cm, group III 2.2 cm and 1.9 cm, group IV 2.3 cm and 1.8 cm, and group V 2.3 cm and 1.6 cm. The conclusion of ethanol extract of betel leaf (Piper betle Linn) at concentrations of 5%, 10% and 15% as antioxidants can heal burns on the skin back of the rabbit's .
PENGARUH EFEK EKSTRAK ETANOL DAUN MURBEI (Morus multicaulis) SEBAGAI ANTIOKSIDAN PADA PARU – PARU TIKUS (Rattus norvegicus) JANTAN YANG DIPAPAR ASAP ROKOK DENGAN PARAMETER HISTOPATOLOGI Muhammad Asri; Rachmat Kosman; Dewi Yuliana
As-Syifaa Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.062 KB) | DOI: 10.33096/jifa.v7i2.2

Abstract

This research aimed to see antioxidant effect of extract ethanol leaves of Murbei (Morus multicaulis) in the lung hispathology of rats who get cigarette smoke exposure. The research method is have been done with experimental, 25 male rats (Rattus norvegicus) with 2-5 month old, body weigh range 100-200 gram were treated for 31 days. Devide in to 5 groups, P1 positive control (has given food and drink), P2 negative control (with cigarette smoke exposure), P3 (a group treated by cigarette smoke exposure and extract ethanol Murbei 100 mg/kgBB), P4 (a group treated by cigarette smoke exposure and extract ethanol Murbei 200 mg/kgBB), P5 (a group treated by cigarette smoke exposure and vitamin E 1,8 mg/kgBB). In 31st day, the mice performed surgery to retrieve organs rat lung histopathology test is then performed. Given ethanol extract of leaves of Murbei (Morus multicaulis) 100 mg/kgBB and 200 mg/kgBB may have an effect as an antioxidant in the lungs of rat (Rattus norvegicus) males
Co-Authors Dewi Yuliana Rachmat Kosman