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All Journal As-syifaa Jurnal Farmasi AL-ULUM: JURNAL SAINS DAN TEKNOLOGI Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Etam Jurnal Farmasi Galenika
Anita Apriliana
Sekolah Tinggi Ilmu Kesehatan Samarinda
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Energy Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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KARAKTERISASI DAN SKRINING FITOKIMIA SIMPLISIA BUAH SELUTUI PUKA (Tabernaemontana macracarpa Jack) Fitri Handayani; Anita Apriliana; Ira Novianti
As-Syifaa Jurnal Farmasi Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (125.191 KB) | DOI: 10.33096/jifa.v12i1.577

Abstract

Selutui puka (Tabernaemontana macrocarpa Jack) is a medicinal plant that grows in forests and river banks. This plant can be found in West Kutai, East Kalimantan. Empirically, the use of selutui puka fruit is used as a medicine for toothache and canker sores by boiling it, the cooking water is used by stew. The importance of simplicia characterization is to determine the quality of simplicia which will become the standard for traditional medicine. The purpose of this study was to determine the characteristics of simplicia powder from selutui puka fruit and to determine the class of chemical compounds contained in selutui puka fruit. This research is non experimental. The research starts from sampling, determination, making simplicia, characterization which includes macroscopic test, microscopic test, determination of moisture content, soluble ethanol extract content, water soluble extract content, moisture content, ash content, acid insoluble ash content and phytochemical screening. Data were analyzed using descriptive methods.Macroscopic and organoleptic characterization of simplicia powder has a distinctive aroma (aromatic), bitter fruit flavor, yellowish-brown simplicia powder, white meat, hard and runny meat. Microscopic results of simplicia powder are found in the endocarp, wooden vessels in the form of stairs, trachea, and cork tissue. The level of dissolved ethanol extract was 36%, water juice content was 47%, water content was 8%, ash content was 4.36%, acid insoluble ash content was 0.57%. The results of phytochemical screening contain alkaloids, saponins, and flavonoids.
KARAKTERISASI DAN SKRINING FITOKIMIA SIMPLISIA DAUN SELUTUI PUKA (Tabernaemontana macracarpa Jack) Fitri Handayani; Anita Apriliana; Hellen Natalia
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.543 KB) | DOI: 10.36387/jiis.v4i1.285

Abstract

Selutui puka (Tabernaemontana macrocarpa Jack) is a plant that is efficacious for treating tumor diseases and blisters. Simplicia is said to be of high quality if it meets the simplicia requirements. The initial process to find out the quality of simplicia is characterization. The study aims to determine the specific, non-specific characteristics and content of chemical compounds.This research is non experimental. The research starts from sampling, determination, making simplicia, characterization which includes macroscopic test, microscopic test, determination of moisture content, soluble ethanol extract content, water soluble extract content, moisture content, ash content, acid insoluble ash content and phytochemical screening. Data were analyzed using descriptive methods.Specific characteristics in the macroscopic and organoleptic tests showed long round leaves, pinnate leaf bones, spiky rounded leaf tips, rounded base of leaves, flat leaf edges, thick leaf flesh, dark green color, leaf width of 4.5 cm long, 12.5 cm long. The powder is dark green, aromatic and has a bitter taste. Microscopic tests include cover hair, vessels, bundles of stairs, upper epidermis and lower epidermis with bidiastic type stomata, 12% soluble ethanol, 15% water soluble extract. Non-specific characteristics consisted of 8% moisture content, 6.51% ash content, acid insoluble ash content 0.246%. The results of phytochemical screening contain alkoloid, flavonoids, tannins, saponins and steroids.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BUNGA KECOMBRANG (Etlingera elatior (Jack) R. M.Sm.) TERHADAP BAKTERI Propionibacterium acnes Yulistia Budianti Soemarie; Anita Apriliana; Achmad Kadri Ansyori; Pipih Purnawati
AL-ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 5, No 1 (2019)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.238 KB) | DOI: 10.31602/ajst.v5i1.2469

Abstract

Acne is one of the skin diseases that disturbs the appearance especially of teenagers. Some types of bacteria that cause acne is Propionibacterium acnes. An alternative natural ingredient that can be used to treat acne is kecombrang flowers (Etlingera elatior (Jack) R.M.Sm.). The purpose of this study was to determine whether the kecombrang ethanol extract has antibacterial activity against the bacteria that caused acne, and to know the effective concentration of the ethanol extract of the kecombrang flower on the bacteria that caused the acne. The research conducted was experimental research. The stages of the study began from the determination of the sample, the manufacture of simplicia powder, extraction of kecombrang flowers using the maceration method, phytochemical screening and antibacterial activity test using the disc diffusion method. The concentrations of extract used in the testing of antibacterial activity were 20%, 40%, 60% and 80%. The results showed that the ethanol extract of the kecombrang flower contained secondary metabolites in the form of flavonoids and saponins. The results of the testing of the antibacterial activity showed that the ethanol extract of the kecombrang flowers had a medium activity at a concentration of 80% against the Propionibacterium acnes bacteria with a inhibition zone of 7,67 mm. Keywords:       Kecombrang flowers (Etlingera elatior (Jack) R.M.Sm.), Antibacterial activity test, Propionibacterium acnes
Analisis Pengawet Natrium Benzoat Pada Kecap Asin Dengan Metode Spektrofotometri UV-Vis Henny Nurhasnawati; Anita Apriliana
Jurnal Farmasi Etam (JFE) Vol 3 No 1 (2023): Volume 3, No. 1, Juni 2023
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v3i1.246

Abstract

Kecap asin merupakan produk olahan kedelai yang digunakan sebagai penyedap masakan. Agar memiliki waktu simpan yang cukup lama, produsen umumnya menambahkan pengawet natrium benzoat, salah satu bahan pengawet yang diperbolehkan dalam bahan makanan. Penelitian ini bertujuan untuk mengidentifikasi dan menetapkan kadar natrium benzoat serta kesesuaian kadar natrium benzoat menurut SNI 01-2543-1999 dalam produk kecap asin yang beredar di Pasar Pagi Kota Samarinda. Identifikasi natrium benzoat dilakukan dengan reaksi warna menggunakan FeCl3 5%, sedangkan penetapan kadar natrium benzoat menggunakan metode Spektrofotometri UV-Vis. Analisis data dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa ketiga sampel yang diuji positif mengandung natrium benzoat ditandai dengan terbentuknya endapan kecoklatan. Kadar natrium benzoat yang diperoleh menunjukkan seluruh sampel memenuhi persyaratan SNI 01-2543-1999 yaitu tidak melebihi ambang batas 600 mg/kg. Kadar natrium benzoat pada sampel A sebesar 157,66 mg/kg ± 1,35, sampel B sebesar 148,65 mg/kg ± 0,20 dan sampel C sebesar 12,90 mg/kg ± 0,27.
PERBANDINGAN METODE MASERASI DAN REFLUKS TERHADAP RENDEMEN EKSTRAK DAUN SELUTUI PUKA (Tabernaemontana macrocarpa Jack) Fitri Handayani; Anita Apriliana; Lisa Ariyanti
JURNAL FARMASI GALENIKA Vol 6 No 1 (2019): Jurnal Farmasi Galenika Volume 6 No. 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Masyarakat suku dayak di Kalimantan Timur secara empiris menggunakan selutui puka pada bagian daun untuk mengobati sakit gigi dan sariawan dengan cara direbus kemudian dikumurkan. Potensi selutui puka sebagai obat tradisional dapat dibuat dalam bentuk ekstrak. Rendemen ekstrak salah satu faktor baiknya suatu metode ekstraksi. Faktor yang mempengaruhi rendemen adalah lama ekstraksi dan akurasi lama waktu yang digunakan berpengaruh terhadap efisiensi proses. Penelitian ini merupakan penelitian eksperimental yang bertujuan untuk mengetahui perbandingan metode maserasi dan refluks terhadap rendemen ekstrak daun selutui puka. Teknik sampling yang digunakan adalah purposive sampling. Tahapan penelitian dimulai dengan pengumpulan sampel, pengolahan sampel, proses ekstraksi, penetapan rendemen, penetapan kadar air dan skrining fitokimia. Metode ekstraksi yang digunakan adalah metode maserasi dan refluks. Analisis data yang digunakan adalah analisis deskriptif dan disajikan dalam bentuk tabel. Hasil penelitian menunjukan bahwa metode refluks menghasilkan nilai rata-rata rendemen tertinggi yaitu sebesar 25,76% dan maserasi menghasilkan nilai rata-rata yaitu sebesar 24,37%. Kadar air ekstrak pada maserasi sebesar 14,67 dan pada refluks sebesar 14,83. Ekstrak daun selutui puka mengandung senyawa metabolit sekunder yaitu alkaloid, flavonoid, tanin dan saponin.
Analisis Pengawet Natrium Benzoat Pada Kecap Asin Dengan Metode Spektrofotometri UV-Vis Henny Nurhasnawati; Anita Apriliana
Jurnal Farmasi Etam (JFE) Vol 3 No 1 (2023): Juni
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v3i1.246

Abstract

Kecap asin merupakan produk olahan kedelai yang digunakan sebagai penyedap masakan. Agar memiliki waktu simpan yang cukup lama, produsen umumnya menambahkan pengawet natrium benzoat, salah satu bahan pengawet yang diperbolehkan dalam bahan makanan. Penelitian ini bertujuan untuk mengidentifikasi dan menetapkan kadar natrium benzoat serta kesesuaian kadar natrium benzoat menurut SNI 01-2543-1999 dalam produk kecap asin yang beredar di Pasar Pagi Kota Samarinda. Identifikasi natrium benzoat dilakukan dengan reaksi warna menggunakan FeCl3 5%, sedangkan penetapan kadar natrium benzoat menggunakan metode Spektrofotometri UV-Vis. Analisis data dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa ketiga sampel yang diuji positif mengandung natrium benzoat ditandai dengan terbentuknya endapan kecoklatan. Kadar natrium benzoat yang diperoleh menunjukkan seluruh sampel memenuhi persyaratan SNI 01-2543-1999 yaitu tidak melebihi ambang batas 600 mg/kg. Kadar natrium benzoat pada sampel A sebesar 157,66 mg/kg ± 1,35, sampel B sebesar 148,65 mg/kg ± 0,20 dan sampel C sebesar 12,90 mg/kg ± 0,27.
ANTIDEPRESSANT ACTIVITY TEST OF RED BETEL LEAF ETHANOL EXTRACT (Piper crocatum) ON MALE WHITE MICE (Mus musculus) USING THE FORCED SWIM TEST METHOD Triswanto Sentat; Anita Apriliana; Siti Lili Rizki Sari; Novi Milasari; Ghina Adhila; Rizki Rahmadi Pratama; M. Hasan Andryanto
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 11, No 2 (2025)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v11i2.18542

Abstract

Red betel leaves (Piper crocatum) contain flavonoids, alkaloids, polyphenols, tannins, and which is known for its antidepressant properties. The purpose of this study was to determine the effect of antidepressant activity of ethanol extract of red betel leaves on male white mice (Mus musculus) orally. The method used in testing antidepressants is the Forced Swim Test. Fifteen mice were divided into five groups: a positive control group receiving 3.5 mg/kg BW amitriptyline, a negative control group, and three groups receiving 200, 400, and 800 mg/kg BW of the extract. The antidepressant effect was measured by observing the immobility of mice during swimming. The results of the study using paired sample t-Test analysis showed that there was a difference in immobility before and after, in the 400 mg/kg BW extract and 3.5 mg/kg BW amitriptyline dose groups had significant differences.
Co-Authors Ansyori, Achmad Kadri Fitri Handayani Fitri Handayani Ghina Adhila Hellen Natalia Henny Nurhasnawati Ira Novianti Lisa Ariyanti M. Hasan Andryanto Novi Milasari Pipih Purnawati Rizki Rahmadi Pratama Siti Lili Rizki Sari Triswanto Sentat Yulistia Budianti Soemarie