Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Medica Hospitalia
Anindita Soetadji
Unknown Affiliation
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Hubungan Kadar Lipid Darah dan hsCRP pada Anak Obesita Anindita Soetadji; Agustini Utari; Rina Pratiwi; Maria Mexitalia; Hertanto W Subagjo
Medica Hospitalia : Journal of Clinical Medicine Vol. 2 No. 3 (2014): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v2i3.190

Abstract

Latar belakang : Obesitas telah menjadi epidemi global karena prevalensi dan komplikasinya baik pada anak maupun dewasa. Meskipun aterosklerosis telah diketahui dimulai pada masa anak, tetapi sampai sekarang belum ada penanda aterosklerosis dini khususnya pada anak. Tujuan penelitian ini adalah mencari hubungan antara kadar lipid darah dengan hsCRP sebagai penanda dini aterosklerosis pada anak. Metode : Desain penelitian adalah belah lintang. Tempat penelitan di SMP Domenico Savio, salah satu SMP di Semarang, yang telah diketahui tinggi angka obesitasnya. Dinilai indeks massa tubuh (IMT) dan persentase lemak tubuh pada murid usia 12-14 tahun, serta kadar lipid darah (kolesterol total, LDL, HDL serta trigliserida) dari darah puasa. Sampel dipilih secara acak, dihitung dengan rumus untuk uji korelasi, dibutuhkan sampel 35 anak obesitas, dan diambil 35 anak normal sebagai pembanding, maka total subyek penelitian minimal adalah 70 orang. Hasil : Terdapat perbedaan kadar trigliserid (95%CI;0,13-0,26) dan hsCRP (95%CI;0,37-0,87) pada kelompok obesitas dan kontrol. Pada seluruh subyek, hsCRP berhubungan sedang dengan IMT (r=0,445;p< 0,05) dan persen lemak tubuh (r=0,44;p<0,05) serta hubungan lemah antara kadar HDL dan hsCRP (r=-0,227; p<0,05). Simpulan : Kadar hsCRP akan meningkat bila terjadi peningkatan IMT dan persentase lemak tubuh, sedangkan kadar HDL kolesterol bersifat protektif terhadap peningkatan hsCRP
Pengaruh Durasi Sakit dan Dosis Kumulatif Prednison terhadap Fungsi dan Geometri Ventrikel Kiri pada Anak dengan Sindroma Nefrotik Muhammad Heru Muryawan; Irma Rezky Ratu; Anindita Soetadji
Medica Hospitalia : Journal of Clinical Medicine Vol. 4 No. 3 (2017): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.248 KB) | DOI: 10.36408/mhjcm.v4i3.331

Abstract

Background: Nephrotic syndrome is a chronic disease that often occurs in children. Treatment with prednison as a first line treatment in nephrotic syndrome plays a role in the process of remodeling and left ventricular hypertrophy. Prevalence of LVH among CKD patients is 34 - 78%. The presence of LVH increases the risk of mortality and morbidity of cardiovascular disorders, so its recomended to determine geometry of left ventricle to see the systolic and diastolic function. Objective: To determine the effect of duration of illness and cumulative prednison dossage on geometry and left ventricular function children with nephrotic syndrome. Methods: A cross sectional study of 27 children between 1 -18 years was conducted in Kariadi hospital, Semarang. Subjects were enrolled by consecutive sampling. The cumulative dose of prednison was calculated based on overall dose received during treatment untill echocardiography were done. Geometric parameter and left ventricular function were determined by M – mode echocardiography. Data were analyzed using bivariate analysis. Results: There is a significant difference between cumulative prednison dossage and left ventricular geometry (p=0.001). Duration of illness (p= 0.60) and cumulative prednison dossage (p=0.44) were not significantly associated with diastolic ventricular function. Conclusion: Cumulative prednison dossage was significantly associated with concentric tipe left ventricular geometry and there is no association with duration of illness. There is no effect of duration of illness and cumulative prednison dossage in diastolic ventricular function. Keywords: Nephrotic syndrome, prednison, left ventricular geometry
Co-Authors Agustini Utari Hertanto W Subagjo Irma Rezky Ratu Maria Mexitalia Muhammad Heru Muryawan Rina Pratiwi