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All Journal JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Neurona
Rr Josephine Retno Widayanti
Fakultas Kedokteran Dan Ilmu Kesehatan Universitas Katolik Indonesia Atma Jaya, Jakarta.
Health Professions Medicine & Pharmacology Neuroscience Public Health

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Diagnosis dan Tatalaksana Terkini Penyakit Neurosistiserkosis Michael Carrey; Endy Suseno; Freggy Spicano Joprang; Octavianus Darmawan; Rr. Josephine Retno Widayanti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss3.art9

Abstract

Cysticercosis occurs in porcine naturally. A human can be infected by cysticercosis if they swallow Taenia solium's egg inadvertently. These eggs can be found in vegetables or unboiled water. These eggs hatch and later will become larva that becomes cysts in muscle or brain, known as cysticercus cellulose. Neurocysticercosis is an infection of the central nervous system caused by Taenia solium at its larval stage. Indonesia is a developing country with a high incidence rate of neurocysticercosis, with the highest amount of cases found in Bali and Papua. Neurocysticercosis boasts a broad array of clinical symptoms, from silent disease to a severe, debilitating illness that leads to death. The diagnosis of neurocysticercosis itself presents a great challenge, due to the unspecific clinical symptoms, in-pathognomonic radiographic findings and serologic studies with low specificity and sensitivity. The management of neurocysticercosis consists of a combination of antiparasitic agents and supportive therapies, ranging from steroid to surgeries that can be done under certain circumstances.
PERBEDAAN SENAM OTAK DAN SENAM POCO-POCO MENINGKATKAN FUNGSI EKSEKUTIF LANSIA: STUDI EKSPERIMENTAL DI PUSAT SANTUNAN KELUARGA Yuliana Yosephine; Rr Josephine Retno Widayanti; Yuda Turana
NEURONA Vol 37 No 2 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i2.111

Abstract

THE DIFFERENCE OF BRAIN GYM AND POCO-POCO GYMNASTICS IMPROVING EXECUTIVE FUNCTION OF ELDERLY: EXPERIMENTAL STUDY IN PUSAT SANTUNAN KELUARGAABSTRACTIntroduction: The elderly have the risk of experiencing executive dysfunction due to structural and functional changes in neurons and synapses in the prefrontal cortex associated with aging. The brain gym and Poco-poco gymnastics can maintain and improve executive function so that productivity and quality of life of theelderlyremainoptimal.Aim: To find out the difference between the effect of brain gym and Poco-poco gymnastics on improving the executive function of elderly population in Pusat Santunan Keluarga (PUSAKA).Method: The study uses an experimental study with a nonequivalent control group design approach. Sixty elderly respondents were dividedinto the brain gym group (n=30) and the Poco-poco gymnastics group (n=30) in two different PUSAKAs. Each interventions are carried out three times a week for 30 minutes in four weeks. Analysis of the differences in the effect of brain gym and Poco-poco gymnastics on executive function of the elderly based on the mean difference in Oral Trail Making Test Form B (OTMT-B) using the Mann-Whitney test.Result: There was an improvement in the mean duration of completion of OTMT-B after the intervention in the brain gym group and Poco-poco gymnastics group with a significant p<0.05. The difference in mean difference between OTMT-B after the intervention in the Poco-poco gymnastics group was higher than the brain gym group.Discussion: The brain gym and Poco-poco gymnastics can improve the function of the elderly executive function. Improved executive function was more significant in the Poco-poco gymnastics group than the brain gym group.Keyword: Brain gym, elderly, executive function, Oral Trail Making Test Form-B, Poco-poco gymnasticsABSTRAKPendahuluan: Lansia berisiko mengalami gangguan fungsi eksekutif karena perubahan struktural dan fungsional pada neuron dan sinaps di korteks prefrontalis terkait penuaan. Senam otak dan senam Poco-poco dapat mempertahankan dan meningkatkan fungsi eksekutif sehingga produktivitas dan kualitas hidup lansia tetap optimal.Tujuan: Untuk mengetahui perbedaan pengaruh senam otak dan senam Poco-poco terhadap peningkatan fungsi eksekutif populasi lansia di Pusat Santunan Keluarga (PUSAKA).Metode: Penelitian menggunakan studi eksperimental dengan pendekatan nonequivalent control group design. Enam puluh lansia sebagai subyek terbagi dalam kelompok senam otak (n=30) dan kelompok senam Poco-poco (n=30) di­ dua PUSAKA. Masing-masing intervensi dilakukan sebanyak tiga kali seminggu selama 30 menit dalam empat minggu. Analisis perbedaan pengaruh senam otak dan senam Poco-poco terhadap fungsi eksekutif lansia berdasarkan selisih rerata Oral Trail Making Test Form B (OTMT-B) menggunakan uji Mann-Whitney.Hasil: Terdapat perbaikan durasi penyelesaian OTMT-B setelah intervensi senam otak dan senam Poco-poco dengan nilai kemaknaan p<0,05. Perbedaan selisih rerata durasi penyelesaian OTMT-B pada kelompok intervensi senam Poco-poco lebih tinggi dibandingkan kelompok senam otak.Diskusi: Intervensi senam otak dan senam Poco-poco dapat meningkatkan fungsi eksekutif populasi lansia. Peningkatan fungsi eksekutif lebih signifikan pada kelompok intervensi senam Poco-poco dibandingkan kelompok intervensi senam otak.Kata kunci: Fungsi eksekutif, lanjut usia, Oral Trail Making Test Form-B, senam otak, senam Poco-poco
HUBUNGAN KOLESTEROL NON-HDL TERHADAP FUNGSI KOGNITIF PADA PASIEN STROKE ISKEMIK DENGAN DEFISIT NEUROLOGIS RINGAN Aylenia Lysandra; Budi Riyanto Wreksoatmodjo; Josephine Retno Widayanti
NEURONA Vol 37 No 3 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i3.163

Abstract

Introduction: Ischemic stroke patients have higher risk of cognitive decline. Severity of cognitive impairment depends on the severity of neurological deficit. The severity of cognitive impairment is also affected by abnormal non-HDL cholesterol level which includes atherogenic lipid that causes atherosclerosis. Aim: Understanding the association of non-HDL cholesterol and cognitive function in mild stroke patients at Atma Jaya Hospital in 2014-2018. Methods: A cross-sectional study by analyzing stroke registry patients (115 subjects). Data is analyzed by using Chi-square test and Fisher exact test. Results: Total sample of this research is 115 respondents. Mean age was 58±11,286 years old and 30,4% graduated from senior high school. 38,3% have cognitive impairment measured by Mini Mental State Examination (MMSE), of which 79.5% have abnormal non-HDL cholesterol. Meanwhile, 70,4% have cognitive impairment measured by Montreal Cognitive Assessment Indonesian Version (MoCA-Ina), of which 76.5% have abnormal non-HDL cholesterol. Cognitive function measured by MMSE and MoCA-Ina has no significant association with non-HDL cholesterol (respectively). Discussion: This research contradicted the previous research. It is suspected that there is no direct relationship between non-HDL cholesterol and cognitive function. Besides, cholesterol acts as antioxidant, has a role in neurotransmission and has a protective effect. Discussion: Cognitive function in patients with mild stroke, measured by MMSE and MoCA-Ina, is not associated with non-HDL Cholesterol. Keywords: Cognitive function, ischemic stroke, mild stroke, non-HDL cholesterol
Co-Authors Aylenia Lysandra Budi Riyanto Wreksoatmodjo Endy Suseno Freggy Spicano Joprang Michael Carrey Octavianus Darmawan Yuda Turana Yuliana Yosephine