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All Journal Damianus Journal of Medicine JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Neurona Acta Neurologica Indonesia
Octavianus Darmawan
Department Of Neurology, School Of Medicine And Health Sciences, Atma Jaya Catholic University Of Indonesia
Health Professions Medicine & Pharmacology Neuroscience Public Health

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Hubungan Fungsi Kognitif Dengan Keseimbangan Pada Lansia Di Jakarta Ireina Karyn; Maria Dara Novi Handayani; Octavianus Darmawan
Bahasa Indonesia Vol 20 No 2 (2021): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v20i2.2639

Abstract

Introduction: The world is entering an aging population. With aging comes many challenges due to changes of the brain structure that affect both cognitive function and balance. The amount of cognitive function and balance impairment cases in the elderly are rising. If left unattended, it can cause numerous adverse effects in the elderly, eventually leading to the loss of the ability to perform activities of daily living. Studies have observed the relationship between cognitive impairment and balance in Indonesia, but only a few were conducted in Jakarta, specifically among elders in the nursing home. This study is aimed to observe the association between cognitive function and balance in the elderly.Methods: This is a secondary analysis using a previous study conducted in PSTW Budi Mulia Jakarta in 2016. Demographic data, cognitive function, and balance were assessed using the demographic questionnaire, Mini-Mental State Examination (MMSE), and Berg Balance Scale (BBS). Statistical analysis is conducted using IBM SPSS Ver 22.Results: Most respondents were female, aged 60-69 years old, had low education level, good MMSE score (53,3%), and a normal BBS (90,7%) score. We found a significant relationship between cognitive functions and balance (p=0,045).Conclusion: Cognitive function is related to balance impairment in the elderly. Key Words: balance, cognitive function, elderly
Diagnosis dan Tatalaksana Terkini Penyakit Neurosistiserkosis Michael Carrey; Endy Suseno; Freggy Spicano Joprang; Octavianus Darmawan; Rr. Josephine Retno Widayanti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 3, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss3.art9

Abstract

Cysticercosis occurs in porcine naturally. A human can be infected by cysticercosis if they swallow Taenia solium's egg inadvertently. These eggs can be found in vegetables or unboiled water. These eggs hatch and later will become larva that becomes cysts in muscle or brain, known as cysticercus cellulose. Neurocysticercosis is an infection of the central nervous system caused by Taenia solium at its larval stage. Indonesia is a developing country with a high incidence rate of neurocysticercosis, with the highest amount of cases found in Bali and Papua. Neurocysticercosis boasts a broad array of clinical symptoms, from silent disease to a severe, debilitating illness that leads to death. The diagnosis of neurocysticercosis itself presents a great challenge, due to the unspecific clinical symptoms, in-pathognomonic radiographic findings and serologic studies with low specificity and sensitivity. The management of neurocysticercosis consists of a combination of antiparasitic agents and supportive therapies, ranging from steroid to surgeries that can be done under certain circumstances.
HUBUNGAN ANTARA RIWAYAT PENYAKIT JANTUNG DENGAN TINGKAT KEPARAHAN STROKE ISKEMIK AKUT PERTAMA KALI Ignatius Ivan; Budi Riyanto Wreksoatmodjo; Octavianus Darmawan
NEURONA Vol 37 No 1 (2019)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i1.101

Abstract

ASSOCIATION BETWEEN HISTORY OF HEART DISEASE AND SEVERITY OF ACUTE FIRST-EVER ISCHEMIC STROKEABSTRACTIntroduction: History of heart disease such as atrial  fibrillation, angina pectoris, myocardial infarction, heart failure has a role on ischemic stroke severity.Aim: This research aims to find the association between history of heart disease and stroke severity using NIHSS score on acute ischemic stroke patients in Atma Jaya hospital during 2014-2018.Method: This research used cross-sectional method with two-sided fisher’s exact test. With total sampling, samples retrieved from secondary sources in Atma Jaya hospital during 2014-2018 resulting 236 subjects. Stroke severity measured by NIHSS score during admission, categorized with severe stroke (15-42) and non-severe stroke (0-14).Result: There is a significant association between history of AF (p=0.046) on first-ever ischemic stroke severity. Acute first-ever ischemic stroke patients who are  >18 years old with history of AF has a tendency of 5,2 times to have severe stroke compared with patients without AF. Other history of heart disease has no significant association towards stroke severity.Discussion: In accordance with previous research, our findings suggest a significant association between history of atrial fibrillation and acute first-ever ischemic stroke severity in which there is a tendency of more severe stroke compared wth patients without AF. Unlike previous findings, this research shows no significant association between history of heart failure and stroke severity due to limited data characteristic  of ejection fraction preventing us to include patient with ejection fraction below 30%. This limitation may also allow history of angina pectoris and myocardial infarction to be insignificant.Keywords:  Atrial  fibrillation,  heart  failure,  ischemic  stroke,  myocardial  infarction,  National  Institutes  of Health Stroke ScaleABSTRAKPendahuluan: Riwayat penyakit jantung seperti atrial fibrilasi, angina pektoris, infark miokardium, gagal jantung memiliki peran terhadap keparahan stroke iskemik.Tujuan: Mengetahui hubungan riwayat penyakit jantung dengan tingkat keparahan stroke berdasarkan skor NIHSS pada pasien stroke iskemik akut di RS Atma Jaya pada tahun 2014-2018.Metode: Penelitian potong lintang terhadap data sekunder pasien stroke iskemik pertama kali yang dirawat di RS Atma Jaya pada tahun 2014-2018. Keparahan stroke diukur berdasarkan National Institutes of Health Stroke Scale (NIHSS) masuk dengan kategori severe stroke (skor 15-42) dan non-severe stroke (0-14). Dilakukan uji Fisher dua sisi untuk menilai hubungan.Hasil: Terdapat 236 subjek dengan mayoritas hubungan riwayat AF (p=0,046) terhadap tingkat keparahan stroke. Pasien berumur >18 tahun yang mengalami stroke iskemik akut pertama kali dengan riwayat AF akan berpeluang 5,2 kali lebih tinggi untuk mengalami severe stroke dibandingkan jika tanpa riwayat AF. Riwayat penyakit jantung lain tidak memiliki hubungan signifikan terhadap tingkat keparahan stroke.Diskusi: Terdapat hubungan yang signifikan antara riwayat AF terhadap tingkat keparahan stroke, terutama pada subjek dengan severe stroke jika dibandingkan pasien tanpa riwayat AF. Tidak ditemukan hubungan signifikan antara penyakit jantung yang lain dikarenakan keterbatasan data penelitian.Kata kunci: Atrial fibrilasi, gagal jantung, infark miokardium, National Institutes of Health Stroke Scale, stroke iskemik
Marital Status As A Predictor of Amnestic Mild Cognitive Impairment in Indonesia Chandra, Fani Agusta; Darmawan, Octavianus
Acta Neurologica Indonesia Vol. 2 No. 01 (2024): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v2i01.22

Abstract

Introduction: Several modifiable risk factors have been identified as the predictors of amnestic mild cognitive impairment (aMCI). However, research focusing on factors beyond biological is limited. Marital status is a psychosocial factor with recognized impact on health that needs further exploration. Objective: This study aimed to evaluate the association between marital status and aMCI amongst older Indonesian population. Material and methods: This was a cross-sectional study of Indonesian Family Life Survey-5. The participants (≥60 years old), excluding individuals with functional dependency, were subdivided into two based on word list recall (WLR) score (cut-off<6.5). Sociodemographic, psychological factors, physical activity, and body mass index were included as predictors. Bivariate and multivariate analyses were conducted. Result: A total of 4287 participants were included. Significant associations were observed between low WLR score and older age, low education, low socioeconomic status, rural residential area, being unmarried, life dissatisfaction, no social engagement, negative affect, and obesity. Multivariate analysis revealed being unmarried was significantly associated with aMCI (AOR 2.38, 95% CI 1.014–5.589, p=0.046), along with older age, low education, low socioeconomic status, and obesity. Discussion: Being unmarried (never married, divorced, or widowed) is a significant predictor of aMCI amongst Indonesian older people. This finding can be explained by the marital resource model and the stress model. Conclusion: This nationwide study is one of the first to explore marital status as a potential yet underexplored factor of aMCI in Indonesia. Being unmarried is associated with an increased risk of aMCI, prompting different approaches in this population.
Co-Authors Budi Riyanto Wreksoatmodjo Chandra, Fani Agusta Endy Suseno Freggy Spicano Joprang Ignatius Ivan Ireina Karyn Maria Dara Novi Handayani, Maria Dara Novi Michael Carrey Rr Josephine Retno Widayanti