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Perbandingan Variasi Pelarut dari Ekstrak Daun Lidah Mertua (Sansevieria trifasciata) terhadap Rendemen dan Aktivitas Antibakteri Dewatisari, Whika Febria
Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) 2019: Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (512.836 KB)

Abstract

Lidah Mertua (Sansevieria trifasciata) memiliki kandungan berbagai macam metabolit sekunder sehingga berpotensi sebagai antibakteri. Salah satu bakteri yang sering menyerang tubuh manusia adalah Escheria coli. Bakteri E. coli merupakan bakteri yang terdapat pada saluran pencernaan manusia dan hewan, namun bakteri ini dapat berubah menjadi oportunis patogen bila hidup di luar usus, misal pada saluran kemih. Dalam penelitian ini dilakukan perbandingan variasi pelarut terhadap rendemen ekstrak Lidah Mertua untuk mendapatkan pelarut yang tepat yang berpotensi sebagai antibakteri. Ekstraksi lidah Mertua dilakukan dengan cara maserasi menggunakan pelarut n-heksan (non polar), aseton (semi polar), dan etanol(polar), menggunakan ekstraksi secara maserasi. Pengujian efektivitas antibakteri ekstrak kasar daun Lidah Mertua dilakukan terhadap bakteri E. coli menggunakan metode sumur difusi. Metode tersebut dilakukan dengan cara mengukur diameter zona bening di sekitar sumuran. Adanya zona bening di sekitar sumuran menunjukkan aktivitas antibakteri. Pelarut yang paling berpotensi sebagai antibakteri dilanjutkan dengan uji KHM (Konsentrasi Hambat Minimum). KHM dilakukan pada konsentrasi 250; 125; 62,5; 31,25; 15,625 mg/mL. Hasil penelitian menunjukkan bahwa etanol merupakan pelarut yang paling berpotensi menghambat pertumbuhan E. coli, hal ini ditunjukkan dengan pembentukan zona bening sebesar 24 mm, 23 mm, dan 24 mm, diikuti oleh n heksan sebesar 19 mm,18 mm, 18mm dan aseton sebesar 18 mm, 17 mm, 15 mm. Nilai KHM ekstrak etanol lidah mertua terhadap bakteri E. coli adalah 125 mg/mL.
Literature Review: Natural Anthelmintic from Moringa Leaves (Moringa oleifera) for Controlling Haemonchus contortus in Goats Wulandari, Aprilia Rizki; Dewatisari, Whika Febria
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10939

Abstract

Haemonchus contortus remains one of the most pathogenic gastrointestinal nematodes in goats, causing substantial productivity losses in small ruminant farming. The increasing resistance and residue concerns associated with synthetic anthelmintics highlight the need for safer, plant-based alternatives. This study aims to review the potential of Moringa oleifera leaves as a natural anthelmintic for controlling Haemonchus contortus infections in goats. A non-systematic literature review was conducted by screening scientific articles published between 2019 and 2024 through Google Scholar using keywords related to alternative natural anthelmintics, control of goat parasites, Haemonchus contortus infection, Moringa oleifera, and plant phytochemical compounds. Relevant in vitro and in vivo studies were analyzed descriptively to evaluate the plant’s phytochemical profile, mechanisms of action, and effectiveness. Findings indicate that Moringa oleifera leaves contain tannins, saponins, flavonoids, alkaloids, and terpenoids that inhibit egg hatching, disrupt larval development, and impair adult worm survival. In vitro studies consistently demonstrate high ovicidal, larvicidal, and vermicidal activity, with inhibition rates comparable to albendazole at higher concentrations. In vivo results also show significant reductions in fecal egg counts (FEC), particularly at doses of 200–400 mg/kg body weight, without reported adverse effects. These outcomes underline the effectiveness and safety of Moringa oleifera leaves as a promising natural anthelmintic. In conclusion, Moringa oleifera represents a viable, environmentally friendly option for integrated parasite control in goats, particularly for reducing infections caused by Haemonchus contortus. Further standardized dosing studies and long-term evaluations are recommended to optimize its practical application in small ruminant health management.
Implementasi Teknologi Tepat Guna Cookies Sambung Nyawa (Gynura procumbens) untuk Pemberdayaan PKK Sidomulyo, Pengasih, Kulon Progo, Yogyakarta Whika Febria Dewatisari; Andina Setyawati; Nuurhidayat Jafar; Dwi Riyanti; Dhimas Setyo Nugroho; Suyatno; Dyah Paminta Rahayu; Putri Cahaya Situmorang; Hartati
Kurnia Mengabdi: Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 2 (2026): Kurnia Mengabdi: Jurnal Pengabdian kepada Masyarakat
Publisher : CV. Kurnia Grup

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61476/j40wcp06

Abstract

In Indonesia, the rising prevalence of diabetes has been accompanied by an increased risk of complications, adversely affecting quality of life and imposing a substantial economic burden on households. The development of functional food innovations based on locally available medicinal plants represents a promising strategy to support the prevention of diabetes-related complications while simultaneously strengthening community economic resilience. Gynura procumbens (sambung nyawa) is recognized for its bioactive potential, particularly in supporting glycemic control and wound-healing processes under diabetic conditions. This community engagement program aimed to implement appropriate technology for processing G. procumbens into functional cookies while strengthening women’s capacity through the Family Welfare Empowerment (PKK) group. The program was conducted in Sidomulyo Village, Kulon Progo Regency, using a Participatory Community Empowerment approach comprising health education, demonstrations and hands-on production, the application of household-scale processing equipment, and initial mentoring. A total of 40 PKK members participated and were divided into five groups. Participants were actively involved in ingredient weighing, dough preparation, shaping, baking, and product evaluation under the guidance of professional chefs. All groups successfully produced functional cookies, while the community partner received production support consisting of five ovens, mixers, digital scales, baking trays, and aprons. The program demonstrates that research downstreaming can be effectively translated into practical skills based on local resources, with the potential to generate value-added functional food products and serve as an initial platform for developing productive PKK-led microenterprises. The cookie formulation used modified cassava flour (MOCAF), a fermented cassava flour, as the flour base because cassava is readily available in Kulon Progo.
Co-Authors Andina Setyawati Dhimas Setyo Nugroho Dyah Paminta Rahayu Hartati Ismi Rakhmawati Leni Rumiyanti Mega Fatimah Rosana Nuurhidayat Jafar Putri Cahaya Situmorang Rakhmawati, Ismi Riyanti, Dwi Rumiyanti, Leni Suyatno To'bungan, Nelsiani Wulandari, Aprilia Rizki Yuliastrin, Adisti