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All Journal Media Kesehatan Masyarakat Indonesia JURNAL GIZI INDONESIA Jurnal Kesehatan Lingkungan indonesia Jurnal Kesehatan Masyarakat Jurnal Kesehatan Masyarakat Jurnal Ilmiah Mahasiswa Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat ASPIRATOR - Journal of Vector-Borne Diseases Studies
Praba Ginandjar
Bagian Epidemiologi, Fakultas Kesehatan Masyarakat, UNDIP
Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Journal : JURNAL GIZI INDONESIA

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Tidak ada perbedaan respon imun perokok berat dan perokok ringan karena asupan mikronutrien Rahfiludin, Mohammad Zen; Ginandjar, Praba
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 2, No 1 (2013)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.963 KB) | DOI: 10.14710/jgi.2.1.

Abstract

Background: Smoking may affect cytokine levels, including IFN-γ, IL-6, and IL-10. Objectives: This study aimed to analyze the difference in levels of cytokines (IFN-γ, IL-6 and IL-10) based on the degree of smoking, and how the daily intake of nutrient influence the relationship of smoking with cytokines level.Method: This was a cross sectional study. Study subject consisted of 23 adult, healthy, smoker men. Ethical clearance was issued by Commission of Ethics of Medical and Public Health Research, Faculty of Public Health Diponegoro University. Smoking variabel was obtained from questions. Level of cytokines examined consists of IFN-γ, IL-6 and IL-10 was measured using ELISA (pg/dl). Nutritional intake was measured by method of 2x24-hour recall. The difference of level of IFN-γ, IL-6, IL-10 and daily nutrient intake based on smoking degree was analyzed with Mann Whitney (α 0,05). Result: The result showed no difference in level of IFN-γ, IL-6 and IL-10 found between group of light and heavy smokers. In the group of heavy smokers, daily nutrient intake was higher compare to light smokers. However, the significant difference only found in vitamin C (p = 0.042). Conclusion: Immune response, as measured by level of interferon gamma, interleukin 6 and interleukin 10, do not differ betwen light and heavy smokers due to micronutrient intake Keywords: heavy smoker, light smoker, interferon gamma, interleukin 6, interleukin 10
Co-Authors Ari Udijono Ari Udiyono Ariyani, Vivi Septi Dina R. Pangestuti Ester Sri Majawati Gambiro Gambiro, Gambiro Hestiningsing, Retno Hidayah, Elma Nur Hidayati Hidayati Jorghi, Herlysse Jorghi Kusariana, Nissa Kusariana Lestari, Dwi Nikmah Lintang Dian Saraswati Mailana, Alfiko Aditya Martini Martini Mohammad Z. Rahfiludin Mohammad Zen Rahfiludin Ningtyas, Angelia Galuh Nissa Kusariana Nugroho, Aldo Arta Nur Endah Wahyuningsih Pranajaya, Condro Sukmo Putri, Fanindita Widyantoro Retno Hestiningsih Sri Yuliawati Suhartati Suhartati Woerjanto, Moh Arie Wulandari, Diana Wurjanto, Moh Arie