Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Farmaka Indonesian Journal of Pharmaceutical Science and Technology
Anis Yohana Chaerunisaa
Faculty of Pharmacy Padjadjaran University
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
FORMULASI EMULGEL ANTIAKNE DENGAN MINYAK MIMBA Anis Yohana Chaerunisaa; Riri Pratiwi
Farmaka Vol 13, No 4 (2015): FARMAKA
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.151 KB) | DOI: 10.24198/jf.v13i4.15432

Abstract

Tanaman mimba (Azadirachta indica A.Juss) merupakan salah satu tanaman obat. Minyak mimba yang berasal dari biji mimba memiliki aktivitas antibakteri. Oleh karena itu pada penelitian dilakukan formulasi sediaan emulgel antijerawat yang mengandung minyak mimba. Bahan aktif minyak mimba dikarakterisasi, kemudian terhadap sampel minyak tersebut dilakukan pengujian aktivitas antibakteri dengan metode difusi agar teknik perforasi. Konsentrasi Hambat Tumbuh Minimum minyak mimba terhadap bakteri penyebab jerawat Staphylococcus aureus adalah 7,5% b/v dan terhadap Staphylococcus epidermidis adalah 10% b/v. Sediaan emulgel antijerawat dengan konsentrasi minyak mimba 15. 20 dan 25% b/v memiliki kestabilan yang baik dalam konsistensi, warna, tekstur dan bau. pH dan viskositas. pH sediaan mengalami perubahan selama penyimpanan, tetapi masih memenuhi persyaratan untuk sediaan topikal dan masih dapat dioleskan dengan baik. Sediaan emulgel antijerawat  dengan konsentrasi minyak mimba 15, 20 dan 25% b/v memiliki daya hambat terhadap bakteri penyebab jerawat. Nilai banding sediaan emulgel minyak mimba terhadap emulgel klindamisin adalah  47,64 : 1 terhadap Staphylococcus aureus dan 39,62 : 1 terhadap Staphylococcus epidermidis. Uji keamanan menunjukkan sediaan emulgel dengan variasi konsentrasi minyak mimba aman digunakan.
Piroxicam Percutaneous Permeation from Gels Through Membrane Models of Shed Snakeskin and Cellulose Anis Yohana Chaerunisaa; Marline Abdassah; Jutti Levita; Ellin Febrina; Ulfinana Hafni
Indonesian Journal of Pharmaceutical Science and Technology Vol 8, No 2 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v8i2.29017

Abstract

Skin has a very important role in determining percutaneous absorption of active substance in topical administration. Study on percutaneous permeation of piroxicam from gel had been conducted using Franz Diffusion Cell with membrane model of shed snakeskin and cellulose. Piroxicam gels were made using Aqupec HV-505 base with 0; 2.5; 5; and 7.5% of DMSO as an enhancer. The results showed that the most stable gel preparation was the one with 5% DMSO (F2), so it was used for further investigation to which percutaneous permeation test. The permeation test was conducted in preparation without and with 5% DMSO (F2) in vitro through shed snakeskin and cellulose membranes. The results showed that F2 increased the permeation rate by as much as 0.0281% per minute. In comparison, the permeation rate of formulation without DMSO (F0) was 0.012% per minute. It can be concluded that DMSO can increase piroxicam penetration through shed snakeskin. Permeation study using cellulose membrane on formula F2 revealed permeation rate as much as 0.006% per minute whereas that without DMSO (F0) was 0.0112% per minute.Keywords: DMSO, cellulose membrane, percutaneous permeation, piroxicam, shed snakeskin.
Co-Authors Ellin Febrina Jutti Levita Marline Abdassah Riri Pratiwi Ulfinana Hafni