Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter
Noratul Hafdhah
Unknown Affiliation
Engineering Other

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The effect of ethanol extracts of pegagan (Centela asiatica) urban in inhibiting the growth of Staphylococcus aureus and Klebsiella pneumoniae that caused pneumonia Zinatul Hayati; Noratul Hafdhah; . Junaidi
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 3, No 3 (2013): Addendum
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.069 KB)

Abstract

Pegagan (Centela asiatica [L] Urban) contains alkaloid, flavonoid, saponin, triterpenoid and tannin that have antibacterial activity. Staphylococcus aureus and Klebsiella pneumoniae are most common of bacteria that cause pneumonia. This study conducted t odetermine the effect of ethanol extracts of pegagan in inhibiting the growth of S. aureus and K. pneumoniae that caused pneumonia. The type of this study is a laboratory experiment using a completely randomized design (CRD). Testing of inhibitory growth effect was measured by Kirby Bauer disc diffusion method. The results showed that ethanol extracts of pegagan at 12.5%, 25%, 50% and 75% concentrations formed inhibition zones on the growth of S. aureus, on average respectively of 7.00 mm, 9.20 mm, 13.20 mm, and 14.50 mm, whereas on the growth of K. pneumoniae, it didn’t form any inhibition zone. The results of ANOVA and Duncan (α=1%) tests showed that ethanol extracts of pegagan at all concentrations made a significant difference in inhibiting the growth of S. aureus compared to negative and positive control. The ability of ethanol extracts of pegagan to inhibit the growth of S. aureus at 12.5% and 25% concentrations categorized as no inhibitory growth effect, whereas 50% and 75% concentrations categorized as weak inhibitory growth effect. While the ethanol extracts of pegagan at all concentrations of the tests categorized as no inhibitory growth effect for K. pneumoniae. It can be concluded that ethanol extracts of pegagan inhibit the growth of S. aureus, but do not inhibit the growth of K. pneumoniae.
Co-Authors . Junaidi Zinatul Hayati