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All Journal Damianus Journal of Medicine Jurnal Kedokteran Meditek
Adelina Simamora
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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AKTIVITAS ANTIOKSIDAN DAN ANTI HIPERKOLESTEROLEMIA EKSTRAK UMBI BAWANG DAYAK (Eleutherine bulbosa [Mill.] Urb) Yani Andryani; Anna Maria Dewajanti; Adelina Simamora
Bahasa Indonesia Vol 21 No 1 (2022): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v21i1.3362

Abstract

Introduction: High cholesterol levels can build up plaque inside the lining of the artery wall leading to coronary heart disease. Dayak onion bulbs (Eleutherine bulbosa (Mill.) Urb) contain flavonoids that can act as antioxidants and are believed to reduce blood cholesterol level. This study investigated the flavonoid content and antioxidant activity of Dayak onion tuber extract, and their effect on total blood cholesterol levels. Methods: Dayak onion bulbs were extracted by maceration (ethanol 70%). Total flavonoid was determined by a colorimetric method using AlCl3. Antioxidant activity was determined based on DPPH radical scavenging activity. Anti-hypercholesterolemia effect was studied in vitro. Thirty-six white male rats (Rattus novergicus) were divided into 6 groups: healthy rats, hyper-cholesterol rats, hyper-cholesterol rats treated with simvastatin (18 mg/bw) and rutin (75 mg/bw) as positive controls, hyper-cholesterol rats treated with dayak union bulbs extracts (75 and 150 mg/bw). Measurement of total cholesterol levels was performed using CHOD-PAP method. Data were analyzed using paired t-test and one-way anova. Results: Flavonoids were present in onion bulb extract with a concentration of 1.7 mg/g dried biomass. The antioxidant activity of the extract (IC50 0.37 mg/mL) was weaker than that of rutin (IC50 15.58 µg/mL). The addition of dayak onion bulbs extract dose of 150 mg/kg bw was the best dose in reducing total blood cholesterol levels on the 14th day, p = 0,001. Conclusion: dayak onion bulbs can be further investigated for application as anti hypercholesterolemia agent.
Efek Tokoferol pada Peroksida Lipid Adelina Simamora
Jurnal Kedokteran Meditek vol. 11 no. 28 April-July 2003
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v11i28.122

Abstract

Bionergetika Adenosin Trifosfat Adelina Simamora
Jurnal Kedokteran Meditek vol. 15 no. 39 Januari-April 2007
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v15i39.184

Abstract

Flavonoid dalam Apel dan Aktivitas Antioksidannya Adelina Simamora
Jurnal Kedokteran Meditek vol. 15 no. 40 Januari-April 2009
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v15i40.192

Abstract

The Potency of CO(Fen)2(NCS)2 Mixed Complex As Indicator of Solvent Acceptor Strenght Adelina Simamora
Jurnal Kedokteran Meditek Vol. 10 No. 27 Januari-April 2002
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v10i27.919

Abstract

Kompleks Besi(II) dengan Lingan 1,10-Fenantrolin 4,7-Dimetil-1,10-Fenantrolin KARAKTERISASI SECARA Spektrometri Ultraungu-Tampak Adelina Simamora
Jurnal Kedokteran Meditek Vol. 7 No. 20 Juli-Oktober 1999
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v7i20.935

Abstract

Komplek Campuran Co(Ii) Dan Mn(Ii) Dengan 1,10-Fenantrolin Dan Rodanida. 1.Studi Pengomplekan Secara Spektrometri Inframerah Adelina Simamora
Jurnal Kedokteran Meditek Vol. 5 No. 13 Oktober-Desember 1997
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v5i13.950

Abstract

Co-Authors Anna Maria Dewajanti Yani Andryani