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Factors Related to the Success of IVF Program in Morula BMC Clinic Padang Nurmala Sari Dewi; Dedy Hendri; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.50-57.2022

Abstract

Introduction: Infertility is the failure of a couple to get pregnant 12 months after having regular sex without contraception. One in seven couples even have to be treated using Assisted Reproductive Technology (TRB). The most widely used TRB is In Vitro Fertilization (IVF). In general, the success rate is in the range of 40-50%. In Indonesia, there are 32 clinics providing IVF program with a success rate of 30-40%. The success rate of IVF is influenced by multi variables that affect directly or indirectly including age, Antral Follicle Count (AFC), Anti Mullerian Hormone (AMH), basal Follicle Stimulating Hormone (FSH), number of egg cells, egg quality, sperm quality, embryo quality, and endometrial thickness. Objectives: This study aims to determine the factors associated with the success of IVF programMethods: This study used a cross-sectional analytic study design which was conducted on 77 medical records of patients undergoing IVF program at Morula Clinic BMC Padang from January 2018-December 2020. All data were then analyzed using univariate, bivariate and multivariate analysis with appropriate statistical test; Results: The average age of the study subjects was (33.4 ± 3.93) years, the average length of infertility was (6.73 ± 3.69) years, the most used antagonist protocols (88.16%), with the most common causes of infertility being factors sperm (48.9%) and overweight BMI (36.4%). From the bivariate analysis, it was found that the factors related to the number of eggs were age (r = -0.349), AFC (r = 0.471), FSH (p 0.02), and AMH (p < 0.01) with the dominant factor being AMH. Egg quality was related to AFC (p 0.007) and FSH (p 0.002), with the dominant factor being AFC. Embryo quality correlated with egg quality (p < 0.01). Meanwhile, the success of implantation was dominantly related to the embryo quality factor (0.034); Conclusion: The most dominant factor to the success of IVF program is the quality of the embryo.Keywords: IVF, IVF success
Pulmonary TB in Pregnancy Efriza Naldi; Nurmala Sari Dewi
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.184-190.2022

Abstract

Objective : To report a case of pulmonary TB in pregnancyMethod : A case reportCase : Presented a case of cpulmonar TB in pregnancy on 33-year-old patient. This is fifth pregnancy with twice history of abortion, malnutrition and pulmonary TB (in treatment). The result of chest x-rays was pulmonary TB. The patient was on treatment for anti-tuberculosis drugs for second month. Patient had BMI was 16,88 kg/m2 which is underweight category. There were bronchovesicular and ronchi from both side of lung from auscultation examination. From laboratory findings there was decrease of albumin serum levels to 2,1 gr%. From ultrasound got impression 16-17 weeks of pregnancy. Patient got anti tuberculosis drugs treatment category I incentive phase (2HRZE). During hospitalization treatment, patient was given some nutrition consultation and high calories and high protein diet and also extra 3 egg whites per day. Total calories are 2250 kcal. Patient also got 1 infuse bottle of albumin and albumin supplementation.Discussion : . The incidence of TB in pregnancy was 1/10,000 pregnancies. .. Provision of an appropriate and adequate chemotherapy regimen will improve the quality of life of the mother, reduce the side effects of anti-tuberculosis drugs (OAT) on the fetus and prevent infection in newborns. Patient got anti tuberculosis drugs treatment category I incentive phase (2HRZE) which is no difference theraphy with no-pregnant patient. Patient was not given pyridoxine as adjuvant drugs along with the anti- tuberculosis drugs. Pyridoxine supplementation must be given with the dose  of 50 mg/day and is suggested for every pregnant woman who consumes isoniazid because the deficiency often happens in pregnancy than general population.Conclusion The diagnosis of this patient was correct based on anamnesis, physical examination, and supporting test . Active TB treatment in pregnancy doesn’t have any difference with non-pregnant. The management of this patient is not correct because the patient didn’t get pyridoxine supplementation, didn’t undergo sputum test in second month, and wasn’t done culture M. Tuberculosis as a gold standard. 
Dandy Walkor Malformation In Trisomy 18 (Edward’s Syndrome): A Rare Case Report Nurmala Sari Dewi; Roza Sriyanti
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3373.181 KB) | DOI: 10.36418/syntax-literate.v7i5.7160

Abstract

Objektif : Trisomi 18 atau sindrom Edward merupakan kelainan genetik autosomal kedua terbanyak yang terjadi pada 1 dalam 6000 kelahiran hidup dengan fenotipe sering menunjukkan kelainan neurologis, keterlambatan kurva pertumbuhan, malformasi organ internal, dan fitur spesifik di wajah, dada, perut, ekstremitas, alat kelamin, kulit, kuku dan rambut. Malformasi Dandy-Walker (DWM) adalah sebuah anomali dari fossa posterior dengan ciri berupa agenesis atau hipoplasia dari vermis dan pembesaran kistik dari ventrikel ke empat menyebabkan perpindahan ke arah atas dari tentorium dan torcula. DWM didiagnosis ketika ada 3 tanda utama muncul pada pasien yaitu agenesis atau hipoplasia dari serebelar vermis, dilatasi kistik dari ventrikel ke empat dan pembesaran fossa posterior. Insiden DWM pada trisomi 18 jarang terjadi dan memiliki prognosis yang buruk. Laporan kasus : Kasus merupakan wanita 36 tahun dengan kehamilan ketiga yang mengeluhkan kehamilan yang sekarang terasa lebih besar dan gerak anak kurang jika dibandingkan dengan kehamilan sebelumnya. Janinnya dicurigai mengalami malformasi Dandy Walker karena dari gambaran USG didapatkan hypoplasia cerebellum dan pembesaran fossa posterior, ditemukan polihidramnion (AFI 27.9 cm) yang kemungkinan disebabkan oleh atresia esofagus. Pada pasien dilakukan amnioreduksi sebanyak 1200 ml dan dilakukan amniosintesis, dari hasil analisis kromosom cairan ketuban didapatkan kariotipe 45,XX+18 (Trisomi 18) atau dikenal dengan Sindrom Edward. Setelah janin lahir didapatkan berat badan 2100 gram dan ditemukan kelainan berupa oksiput yang menonjol, low set ear, pembukaan mulut yang kecil, atresia esofagus, clenched fist yang sesuai untuk gambaran sindrom Edward. Pada bayi dilakukan tindakan Gastrostomi, tetapi kondisi bayi makin memburuk dimana bayi kemudian meninggal pada hari ke 10. Kesimpulan: malformasi dandy Walker pada Trisomi 18 jarang ditemukan dan memilki prognosis yang buruk
Application of Agro-industrial Solid Waste as Biochar for Iron (II) Removal from Aqueous Solution Rusnam Rusnam; Nika Rahma Yanti; Aninda Tifani Puari; Nurmala Sari
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol 13, No 1 (2024): March 2024
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtep-l.v13i1.155-164

Abstract

In recent years, various industrial activities have introduced a high concentration of iron in the waterbody which causes serious problem to environment. This paper proposed the application of Exhausted Coffee Husk (ECH) as the biosorbent (BS) for removing iron (Fe) (II) in the aqueous solution. The ECH was carbonized into biochar before performing biosorption of the heavy metal ion. The effect of carbonization temperature, time and rate on the performance of the ECH biochar for removing Fe (II) were evaluated. The percentage of removal efficiency (RE) and the capacity of biosorption (mg/g) were considered as the determining parameters. The pyrolysis temperature was varied in a range of 200-600 °C with 50 °C of interval, while the time was in between 1h – 3h with a n interval of 0.5 h, and the temperature gradient of 5 – 25°C/min. The results showed that the temperature had a significant effect on the properties of the ECH biochar as BS for Fe (II). The temperature of 550 °C, at 1.5 h of time and 25 °C/min was chosen as the suggested carbonization temperature of biochar from ECH for biosorption of Fe (II).  Keywords:  Agro-industrial solid waste, Biosorption,  Carbonization, Exhausted coffee husk (ECH), Heavy metal.   
Response Surface Methodology (RSM) for Optimization Carbonization Parameters of Exhausted Coffee Husk for Iron Removal from Aqueous Solution Aninda T. Puari; Nika R. Yanti; Nurmala Sari; Rusnam Rusnam
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol 13, No 3 (2024): September 2024
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtep-l.v13i3.637-649

Abstract

In this study, biochar derived from exhausted coffee husk (ECH) was used as biosorbent for removing Iron (II) from aqueous solution. The aim of this study was to improve the biosorption capacity of the biosorbent from agricultural solid waste and its usability for Fe²⁺ removal. The biosorption performance of ECH biochar was optimized through carbonization parameters: temperature, time, and temperature gradient. Response Surface Methodology (RSM) based on multivariate analysis was employed to evaluate the biosorption performance of ECH biochar for Fe²⁺ biosorption. The optimum performance predicted through Box-Behnken design experiment. The optimal combination of the three parameters was 549.37°C, 1.98 h and 21.98°C/min. At the optimal condition the removal efficiency (RE) was predicted to be 107.01% and biosorption capacity (qt) was 5.11 mg/g. SEM-EDX, FT-IR and XRD analysis were conducted in this study to evaluate the biosorption mechanism of ECH biochar on the iron ion. The results showed that ion exchange existed on the surface of the ECH biochar during the biosorption. Additionally, the presence of functional groups on the ECH biochar surface responsible for Fe(II) binding. Overall, the findings of this study suggested an eco-friendly strategy for optimizing the removal of Iron (II) from polluted water by the biosorption onto ECH biochar. Keywords: Biochar, Biosorption capacity, Box-Behnken design, Temperature, Time