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All Journal BIO-SITE |BIOLOGI Sains Terapan Abdi Dosen : Jurnal Pengabdian Pada Masyarakat
Iwang Yusuf
Universitas Islam Sultan Agung
Religion Agriculture, Biological Sciences & Forestry Humanities Education Public Health Social Sciences

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UPAYA PENINGKATAN PENGETAHUAN MASYARAKAT TENTANG MAKANAN PENAMBAH STAMINA DAN IMUNITAS DI MASA PANDEMI COVID-19 Israhnanto Isradji; Iwang Yusuf; Suparmi Suparmi
Abdi Dosen : Jurnal Pengabdian Pada Masyarakat Vol. 6 No. 1 (2022): MARET
Publisher : LPPM Univ. Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (774.731 KB) | DOI: 10.32832/abdidos.v6i1.1092

Abstract

Currently, in the era of the covid-19 pandemic, to prevent the spreading of SARS-CORV2 infection, the public is advised to comply with health protocols and maintain stamina and immunity. Our community service activity (Pengabdian kepada Masyarakat/ PkM) was conducted to increase public knowledge, especially housewives to comply with health protocols and utilize traditional medicinal plants such as ginger, turmeric, and garlic to increase stamina and immunity. The knowledge improvement was evaluated by comparing the pre-test and post-test result using a questionnaire. Data was collected from 38 participants out of 50 participants who fulfilled the questioners. The T-paired test showed that the participant knowledge on covid-19 protocol and natural products for immune system was increased significantly (p<0.05). A 65.8% of participants understands the efforts to prevent the transmission of covid-19 “Protocol 5M” namely Wearing Masks, Washing Hands with Soap, Keeping Distance, Preventing Crowds, and Restricting Mobility. The awareness of participants on the benefit of herbal product to improve stamina and immunity was also improved. A training or workshop for participants in preparing healthy and safe food to avoid side effects can be considered for the next PkM activities.
SELEKTIVITAS ANTIKANKER EKSTRAK DAUN SIRSAK (Annona muricata) PADA LINI SEL KANKER PAYUDARA Dina Fatmawati; Suparmi Suparmi; Iwang Yusuf; Israhnanto Isradji
BIO-SITE |Biologi dan Sains Terapan Vol. 4 No. 2 (2018): Bio-Site
Publisher : Biology Department, Faculty of Science and Technology, Univeristas Jambi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (274.984 KB) | DOI: 10.22437/bs.v4i2.5440

Abstract

Studies have been conducted on cytotoxicity of sirsak (Annona muricata) against T47D cell line. However, the selectivity of Annona muricata leaf extract against MCF-7 breast cancer has not established. This study aimed to determine the index selectivity of Annona muricata leaf extract against MCF-7 breast cancer cell line. In this quasy experimental study using 2 kind of cell line, The MCF-7 breast cancer cell line and Vero cell line as normal cell were treated with Annona muricata leaf extract at dose 1000, 500, 250, 125, 62.5, 31.5 µg/mL respectively. The MTT assay were used to evaluate the viability of both cell line after treatment with Annona muricata leaf extract. The data of viability cells were analyzed with Probit regression to determine the IC50 value of Annona muricata leaf extract in both cell lines. The selectivity of two treatment was determine based on the selectivity index (SI) that represents the ratio of IC50 value of Annona muricata leaf extract. The IC50 value of MCF-7 and normal cell were 44.94 and 184.04 respectively with selectivity index 4. This result suggested that Annona muricata had cytotoxic effect in MCF-7 breast cancer cell line but not in normal cells. In conclusion Annona muricata leaf extract has cytotoxic effect to MCF7 breast cancer cell selectively.
Co-Authors Dina Fatmawati Israhnanto Isradji Suparmi