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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Daldiyono Hardjodisasto
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Medicine & Pharmacology

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Management of Duodenal Ulcer with Gastroesophageal Reflux Disease (GERD) with Intravenous Pantoprazole Ari Fahrial Syam; Murdani Abdullah; Marcellus Simadibrata; Dadang Makmun; Chudahman Manan; Daldiyono Hardjodisasto
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 4, NUMBER 1, April 2003
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/41200326-28

Abstract

Proton pump inhibitors (PPIs) are the most effective anti secretory drugs available for controlling gastric acid acidity and volume. They are the drug of choice in the treatment for gastro esophageal reflux disease (GERD), Helicobacter pylori eradication, peptic ulcer and non steroidal anti-inflammatory drug (NSAID) gastropathy: For acute cases, an intravenous PPI is needed, especially for hospitalized patient. Recently, intravenous pantoprazole represents an alternative to intravenous histamine-2 receptor antagonists. We observed 2 patients who were treated with pantoprazole for duodenal ulcer, where one case had a complication of bleeding with a history of long term use of NSAID. After two weeks of treatment with pantoprazole, significant lesion healing from endoscopy findings was achieved in both cases. Keywords: peptic ulcer, upper gastrointestinal bleeding, proton pump inhibitors, pantoprazole
Co-Authors Ari Fahrial Syam Chudahman Manan Chudahman Manan Dadang Makmun Marcellus Simadibrata Marcellus Simadibrata Murdani Abdullah Murdani Abdullah