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Kemampuan Daya Hambat Beberapa Produk Sampo Antiketombe Dengan Kandungan Bahan Aktif Berbeda Terhadap Jamur Candida albicans Dewi, Resmila; Marniza, Erda; Anggraeni, Widya; Kaliu, Sutriani
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.18749

Abstract

Ketombe merupakan suatu kondisi yang tidak normal pada kulit kepala yang disebabkan oleh infeksi jamur Candida albicans. Penggunaan sampo antiketombe saat keramas membantu menghambat pertumbuhan jamur tersebut. Sampo antiketombe mengandung berbagai bahan aktif yang berperan dalam mengurangi infeksi pada kulit kepala dan menghambat pertumbuhan jamur penyebab ketombe. Tujuan dari penelitian ini adalah untuk menentukan kemampuan daya hambat antijamur beberapa sampo antiketombe dengan bahan aktif berbeda terhadap C. albicans. Uji kemampuan daya hambat dilakukan dengan metode difusi cakram. Data yang diperoleh kemudian dianalisis dengan Analysis of Varience (ANOVA) menggunakan SPSS 27 dan dilanjutkan dengan uji DMRT. Hasil penelitian yang dilakukan terhadap enam sampo antiketombe dengan bahan aktif berbeda yaitu piroctone alamine, selenium sulfida, tea tree oil, asam salisilate, ketokonazole dan zinc pyrithione menunjukkan bahwa masing-masing memiliki perbedaan yang signifikan dalam menghambat jamur C.albicans dengan diameter zona hambat sebesar 20 mm, 30 mm, 18 mm, 29 mm, 34, mm dan 41 mm. Berdasarkan zona hambat yang terbentuk, maka dapat disimpulkan bahwa sampo antiketombe yang mengandung bahan aktif zinc pyrithione memiliki aktivitas daya hambat lebih baik terhadap jamur C.albicans dibanding dengan sampo yang mengandung bahan aktif lainnya.
Antibacterial Activity Of Nutmeg Seed (Myristica fragrans Houtt.) Methanol Extract Against The Growth Of Staphylococcus aureus and Eschericia coli Dewi, Resmila; Kurniaty, Rina; Marniza, Erda
JURNAL BIOSAINS Vol. 11 No. 1 (2025): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v11i1.64594

Abstract

Nutmeg seeds (Myristica fragran Houtt.) are natural materials containing active compounds with potential antibacterial properties. This study aims to determine the antibacterial activity of nutmeg seed methanol extract and the effective concentration for inhibiting the growth of S. aureus and E. coli, as well as to compare the inhibition zones produced against both bacteria. The nutmeg seed extract was obtained through maceration extraction using 96% methanol solvent. The antibacterial activity was tested using the disc diffusion method with three different concentrations of the extract: 20%, 30%, and 40%, along with chloramphenicol (positive control) and 10% DMSO (negative control). The inhibition zone data were analyzed using ANOVA with SPSS 26, followed by the DMRT test. Phytochemical testing revealed that the methanol extract of nutmeg seeds positively contains alkaloids, saponins, flavonoids, quinones, and triterpenoids. The results showed that the methanol extract of nutmeg seeds at concentrations of 20%, 30%, and 40% produced inhibition zones against S. aureus of 11.83 mm, 12.56 mm, and 15.06 mm, respectively, and against E. coli, the inhibition zones measured 11.83 mm, 12.56 mm, and 15.06 mm. The study concludes that the methanol extract of nutmeg seeds exhibits strong antibacterial activity against S. aureus and E. coli, with the most effective concentration being 40%. Additionally, the nutmeg seed methanol extract tended to have better antibacterial properties against E. coli than against S. aureus.
UTILIZATION OF CINNAMON BARK (Cinnamomi burmannii cortex)AS A HERBAL PRODUCT: PEMANFAATAN KULIT KAYU MANIS (Cinnamomi burmannii cortex)SEBAGAI PRODUK HERBAL Rina Kurniaty; Resmila Dewi; Cut Suraiya Wahyuni Utami; Erda Marniza; Widya Angreni
WISDOM : Jurnal Pengabdian Kepada Masyarakat Wisdom Vol. 2 No. 2 (2025): JPKM WISDOM 4, 2025
Publisher : PT. ROCE WISDOM ACEH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71275/wisdom.v2i2.108

Abstract

Cinnamon is a species of the genus Cinnamomum, family Lauraceae, a woody plant commonly knownfor its use as a spice. A natural ingredient rich in benefits, with a distinctive aroma, is widely used forvarious purposes, including flavoring food and cakes. The most significant chemical componentspresent are cinnamic alcohol, coumarin, cinnamic acid, cinnamaldehyde, anthocyanin, and essential oil,along with sugars, proteins, simple fats, pectin, and other compounds. The extraction results ofCinnamomum burmanii bark contain the main antioxidant compounds in the form of polyphenols(tannins, flavonoids) and phenolic group essential oils, which have antimicrobial, antifungal, antiviral,antioxidant, antitumor, blood pressure-lowering, cholesterol-lowering, and low-fat properties. Thisactivity of making cinnamon bark herbal products in the form of rajangan, powder, and capsulepreparations can provide students with information, education, knowledge, and skills, as an alternativemedicinal preparation derived from natural ingredients.
ANTIBACTERIAL ACTIVITY TEST OF PINEAPPLE JUICE (Ananas comosus L.) AGAINST THE GROWTH OF Escherichia coli: UJI AKTIVITAS ANTIBAKTERI SARI NANAS (Ananas comosus L.) TERHADAP PERTUMBUHAN Escherichia coli Resmila Dewi; Cut Suraiya Wahyuni Utami; Erda Marniza; Widya Angreni; Rina Kurniaty
ROCE : Jurnal Pertanian Terapan Vol. 3 No. 1 (2026): JPT ROCE 5, 2026
Publisher : PT. ROCE WISDOM ACEH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71275/roce.v3i1.175

Abstract

Pineapple (Ananas comosus L.) is known to contain active compounds that have antibacterial potential. This study aims to evaluate the antibacterial activity of pineapple juice and determine the effective concentration required to inhibit the growth of Escherichia coli. The antibacterial activity test was conducted using the disc diffusion method at three concentrations (20%, 25%, and 30%), with chloramphenicol as the positive control and distilled water as the negative control. The antibacterial activity test showed that pineapple juice at 20%, 25%, and 30% produced inhibition zones against Escherichia coli of 13.83 mm, 16.33 mm, and 18.50 mm, respectively. Based on the study results, pineapple juice shows antibacterial activity against Escherichia coli, with the most effective concentration for inhibiting bacterial growth at 30%.
UTILIZATION OF  BLU-PEA FLOWERS (Clitoria ternatea)AS AN ANTIOXIDANT IN FOOD AND DRINKS IN LUTHU DAYAH KRUENG VILLAGE, SIBREH, ACEH BESAR: PEMANFAATAN BUNGA TELANG (Clitoria ternatea) SEBAGAI ANTIOKSIDAN PADA MAKANAN DAN MINUMAN DI DESA LUTHU DAYAH KRUENG, SIBREH, ACEH BESAR Widya Angreni; Erda Marniza; Rina Kurniaty; Resmila Dewi; Cut Suraiya Wahyuni Utami
WISDOM : Jurnal Pengabdian Kepada Masyarakat Wisdom Vol. 3 No. 1 (2026): JPKM WISDOM 5, 2026
Publisher : PT. ROCE WISDOM ACEH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71275/wisdom.v3i1.156

Abstract

This Community Service activity was carried out in Luthu Dayah Krueng Village, Sibreh, Aceh Besar Regency, on February 10, 2022, with the theme of Utilization of Butterfly Pea Flowers (Clitoria ternatea) as Antioxidants in Food and Beverages. The target of this program was residents of Luthu Dayah Krueng Village, totaling 40 people aged 30 to 70, including men and women. In its implementation, the methods used were lectures, demonstrations, and question-and-answer sessions. Overall, the implementation of this community activity program went well, was safe, and adhered to procedures. It is hoped that the results of this Community Service activity will deepen the community’s understanding of the proper use of Butterfly Pea Flowers (Clitoria ternatea) to be made into food products, especially food and beverages.