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PENURUNAN INTERDIALYTIC WEIGHT GAIN PASIEN HEMODIALISA DENGAN MENGGUNAKAN APLIKASI THEORY OF PLANNED BEHAVIOUR irma sari
Jurnal Kesehatan Hesti Wira Sakti Vol. 6 No. 1 (2018)
Publisher : Institut Teknologi, Sains, dan Kesehatan RS dr. Soepraoen Malang

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Abstract

Latar belakang : Untuk mengetahui jumlah cairan yang masuk selama periode interdialitik dapat dilakukan dengan mengukur Interdialytic Weight Gain (IDWG). Pengontrolan nilai IDWG selama periode hemodialisa dapat dipengaruhi oleh kepatuhan dalam pembatasan cairan. Pemberian edukasi terstruktur berlandaskan Theory of Planned Behaviour tentang asupan cairan dapat memberikan keyakinan pada pasien gagal ginjal kronik tahap akhir yang menjalani hemodialisa sehingga berdampak pada penurunan IDWG. Tujuan Penelitian : untuk menganalisis penurunan Interdialytic Weight Gain (IDWG) pasien hemodialisa melalui aplikasi Theory of Planned Behaviour. Metode Penelitian : Quasy experiment dengan menggunakan pretest postest with control group design. Sampel dalam penelitian adalah pasien yang menjalani hemodialisa rutin di RSUD Panembahan Senopati Bantul sebanyak 44 orang dengan consecutive sampling. Analisis menggunakan paired t test. Hasil : Terdapat penurunan nilai IDWG pada kelompok intervensi sebelum dan setelah diberikan edukasi Theory of Planned Behaviour dengan nilai p value 0,001. Kesimpulan : Edukasi berlandaskan Theory of Planned Behaviour dapat digunakan untuk menurunkan nilai Interdialytic Weight Gain (IDWG) pasien hemodialisa di Unit Hemodialisa RSUD Panembahan Senopati Bantul. Kata Kunci : hemodialisa, interdialytic weight gain, Theory of Planned Behaviour
THE CYTOTOXIC ACTIVITY OF N-HEXANE EXTRACT OF KERSEN(muntingia calabura linn.) LEAVES USING THE BRINE SHRIMP LETHALITY TEST (BSLT) METHOD Irma Sari; Titania Miranda; Sadli Sadli
Jurnal Natural Volume 16, Number 2, September 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.783 KB) | DOI: 10.24815/jn.v16i2.5124

Abstract

The cytotoxic activity experiment of n-hexane extract of kersen (Muntingia calabura Linn.) leaves has been carried out using the Brine Shrimp Lethality Test (BSLT) method. The purpose of this research is to identify the secondary metabolites, extract characterize, and determine the LC50 value of the extract against larvae shrimp Artemia salina Leach. Screening result showed that n-hexane extract of kersen leaves contain triterpenoid. Extract characterization showed the results water content of 2.59±0.18 %w/w, water soluble extractive content of 1.9%±0.19 %w/w, the ethanol soluble extractive content of 17.41±1,87 %w/w and total ash value 0.25% w/w. Extract showed LC50 value is 278,72 ppm were calculated by probit analysis. The LC50 value indicated that the n-hexane extract of kersen leaves potentially has cytotoxic activity.
THE CHARACTERIZATION OF SIMPLISIA, ISOLATION AND IDENTIFICATION OF CHEMICAL CONSTITUENS FROM THALLUS Turbinaria decurrens Bory Irma Sari
Jurnal Natural Volume 15, Number 2, September 2015
Publisher : Universitas Syiah Kuala

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Abstract

The characterization of simplisia, phytochemical screening, extraction, isolation and identification of chemical constituens  from thallus Turbinaria decurrens Bory have been carried out. The examination of simplisia characteristics gave the water soluble extract the value of 10.59%, ethanol soluble extract valued at 0.93%, total ash valued at 15.64%, the acid insoluble ash value 0.79% and the water content valued at 8.66%. The result of phytochemical screening showed that there was triterpens/steroids present. The extraction process was carried out by percolation and then was separated by liquid vacum column chromatography. Then by preparative thin layer chromatography isolate B1 was obtained. The analysis of isolate B1 by infra red spectrophotometry showed hydroxyl, aliphatic C-H bond, C=O bond, double bond of C=C, C=O bond, C=H bond of CH3 and CH2, were present. Ultra violet spectrophotometry exhibited a maximum absorption at 242 nm and mass spectrometric fragmentation pattern exhibited that the molecular weight of isolate B1 was 394, it was suspected ergosta -4,7,22 –trien -3 one.
THE CYTOTOXIC ACTIVITY OF ETHYLACETATEFRACTION OF KERSEN (Muntingia Calabura) LEAVES AGAINST LARVAE SHRIMP ARTEMIA SALINA LEACH Sadli .; Nurul Wahyu Utami; Irma Sari
Jurnal Natural Volume 15, Number 2, September 2015
Publisher : Universitas Syiah Kuala

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Abstract

Abstract. The cytotoxic activity experiment of ethylacetatefraction of kersen (Muntingia calabura) leaves has been carried out using the Brine Shrimp Lethality Test (BSLT) method withf ive concentration variables; they are 10 ppm, 100 ppm, 200 ppm, 500 ppm, and 1000 ppm. The research aims to determine the secondary metabolite; the extract characterization and determine cytotoxic activity of the ethyl acetate fraction of kersen (Muntingia calabura L.) leaves. Extraction was done with maceration method using ethyl acetate solvent to the kersen dried leaves dregs of n-hexane extract and the value of LC50 was determine by using probit analysis. The results of phytochemical screening showed that ethyl acetate fraction of kersen (Muntingia calabura) leaves contained three secondary metabolites, namely tannin, saponin and flavonoid with extract characterization results are the water content of 3.85%3 ± 0.35%, the water soluble extractive of 17.65% ± 0.27%, ethanol soluble extractive of 62.24% ± 0.07%, the total ash value of 0.89%± 0.005%, and acid insoluble ash value of 0.69%± 0.004%. The LC50 value of ethyl acetate fraction of kersen (Muntingia calabura) 84.92 ppm showed that the extract has  cytotoxic activity as medium toxic.
THE CYTOTOXIC ACTIVITY OF N-HEXANE EXTRACT OF KERSEN(muntingia calabura linn.) LEAVES USING THE BRINE SHRIMP LETHALITY TEST (BSLT) METHOD Irma Sari; Titania Miranda; Sadli Sadli
Jurnal Natural Volume 16, Number 2, September 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v16i2.5124

Abstract

The cytotoxic activity experiment of n-hexane extract of kersen (Muntingia calabura Linn.) leaves has been carried out using the Brine Shrimp Lethality Test (BSLT) method. The purpose of this research is to identify the secondary metabolites, extract characterize, and determine the LC50 value of the extract against larvae shrimp Artemia salina Leach. Screening result showed that n-hexane extract of kersen leaves contain triterpenoid. Extract characterization showed the results water content of 2.59±0.18 %w/w, water soluble extractive content of 1.9%±0.19 %w/w, the ethanol soluble extractive content of 17.41±1,87 %w/w and total ash value 0.25% w/w. Extract showed LC50 value is 278,72 ppm were calculated by probit analysis. The LC50 value indicated that the n-hexane extract of kersen leaves potentially has cytotoxic activity.
Pemanfaatan Bahan Ajar Berbasis Kearifan Lokal Dalam Pembelajaran Sains Di Sekolah Dasar Indriyani Indriyani; Nurul Anisa; Irma Sari; Minawar Minawar; Riski Andrianingsih
Jurnal Sultra Elementary School Vol 5 No 1 (2024): Edisi Juni 2024
Publisher : Prodi PGSD Unsultra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64690/jses.v5i1.408

Abstract

The use of local wisdom-based teaching materials in science learning in elementary schools offers a relevant and contextual approach to improving students' understanding of science. This article aims to explore the literature related to the integration of local wisdom in science learning, focusing on its impact on students' understanding, environmental awareness, and the development of science skills. This study shows that the use of local wisdom can enrich teaching materials, increase student engagement, and foster an attitude of caring for the environment. The method used in this article is a literature study by analyzing various studies related to local wisdom in the context of science education. It was found that despite challenges in implementation, local wisdom-based teaching materials provide significant benefits in a more inclusive and relevant learning context for elementary school students.