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Alergi susu sapi Mulya Safri
Jurnal Kedokteran Syiah Kuala Vol 8, No 1 (2008): Volume 8 Nomor 1 April 2008
Publisher : Universitas Syiah Kuala

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Daftar pustaka1. Lifsehitz C, Alergy to cow milk. J.Ped. Neonatal 2005;2:1-7.2. Muraro A, Dreborg S, Halken S et al, Dietary prevention of allergic diseases in infant and small children Part Ill: Critical review of published peer-reviewed observational and interventional studies and final recommendation. Pediatr Allergy Immunol,2004; 15:291-3073. Sampson HA. Adverse reactions to foods.Dalam: Middleton E, Reed CE, Elliot EF, Adkinson NF, Yunginger JW, Busse WW, penyunting. Allergy, Principle and Practice.Edisi ke-4.St.Louis, Mosby,1993:h 1661- 86.4. Host A. Halken S. Approach to feeding problems in the infant and young child. Dalam: Leung DYM, Sampson HA, Geha RS, Szefler SJ, penyunting. Pediatric Allergy principles and practice. Missouri, Mosby, 2003.h.488-94.5. Ebisawa M, Sugizaki C, Ikeda Y, Tachimoto H.Development of food allergy during infancy. APAPARI-KAPARD Joint congress. Seoul, Korea. April 2005.6. Sampson HA.Food allergy. Part I:lmmunopathogenesis and clinical disorders. J.Allergy Clin lmmunol 1999;103:717-287. Burks AW, James JM,Hiegel A,Wilson G, et al.Atopic dermatitis and food hypersensitivity reactions. J Pediatr 1998;132:132-68. Sicherer Sh,Sampson HA.Food hypersensitivity and atopic dermatitis: Pathofysiology, epidemiology, diagnosis and management J Allergy Clin lmmunol1999; 104:Sl 14-sl229. Hill DJ, Duke AM, Hosking CS,et al.Clinical manifestations of cow's milk allergy in childhood:II.The diagnosis value of skin tests and RAST. Clin Allergy 1988;18:481-9010. William LW, Bock SL. Skin testing and food challenges for evaluation of food allergy. Immunology and Allergy Clinics of North Amer 1999;19:479-931 L Bishop MJ, Hasting. Naturai history of cow's milk allergy. Clinical outcome. J Pediatr 1990;116:862-7.12. Vanto T, Helpplia S, Juntunen-Backman K, Kalimo K, Klemola T, Korpela R. Prediction of the development of tolerance to milk in children with cow's milk hypersensitivity. J Pediatr 2004;144:218-2213. Eggesbo M, Halvorsen R, Tambs K. Prevalence of parentally perceived adverse reaction to food in young children. Pediatr Allergy lmmunol 1999;10:122-32.14. Host A., Halken S. A prospective study of cow's milk alergy in Danish infants during the first 3 years of life. Alergy 1990;45:587-96.15. Hest A. Cow's milk protein alergy and intolerance in infancy. Some clinical, epidemiological and immunological aspects. Pediatr Allergy lmmunol1994;5:l-3

HUBUNGAN FAKTOR PENGETAHUAN, SIKAP, PENDIDIKAN, SOSIAL BUDAYA, EKONOMI KELUARGA SERTA PERAN PETUGAS KESEHATAN TERHADAP RENDAHNYA PEMBERIAN ASI EKSKLUSIF Mulya Safri
Jurnal Kedokteran Syiah Kuala Vol 13, No 1 (2013): Volume 13 Nomor 1 April 2013
Publisher : Universitas Syiah Kuala

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Abstrak. Air Susu Ibu (ASI) eksklusif adalah pemberian ASI saja kepada bayi tanpa makanan atau minuman tambahan sampai bayi berusia 6 bulan. Pemberian ASI eksklusif pada bayi hingga usia 6 bulan dipengaruhi oleh berbagai faktor antara lain pengetahuan, sikap, pendidikan, sosial budaya, ekonomi keluarga dan petugas kesehatan. Penelitian ini bertujuan untuk mengetahui hubungan faktor pengetahuan, sikap, pendidikan, sosial budaya, ekonomi keluarga serta peran petugas kesehatan terhadap rendahnya pemberian ASI eksklusif. Penelitian merupakan penelitian deskriptif analitik dengan pendekatan cross sectional. Sampel diambil dengan teknik total sampling sebanyak 111 orang ibu-ibu yang memiliki bayi usia 6-12 bulan. Penelitian ini memperlihatkan 12% ibu menyusui secara eksklusif dan 88% yang tidak menyusui secara eksklusif. 64% ibu memiliki pengetahuan yang baik mengenai ASI eksklusif, 54% sikap ibu tidak mendukung praktek pemberian ASI eksklusif, 53% ibu berada pada kategori pendidikan dasar, 58% sosial budaya ibu tidak mendukung praktek pemberian ASI eksklusif, 65% ibu berada pada tingkat ekonomi keluarga menengah dan 60% ibu mendapat dukungan dari petugas kesehatan mengenai pemberian ASI eksklusif. Faktor-faktor yang berhubungan dengan rendahnya pemberian ASI eksklusif di Kecamatan Cot Glie Aceh Besar yaitu faktor pengetahuan (p=0,004), sikap (p=0,000), pendidikan (p=0,000), sosial budaya (p=0,000) dan petugas kesehatan (p=0,012). Sedangkan faktor ekonomi keluarga (p=0,074) tidak memiliki hubungan dengan rendahnya pemberian ASI eksklusif di wilayah tersebut. (JKS 2013; 1:23-32 ) Kata kunci : Pemberian ASI eksklusif, bayi, faktor-faktor Abstract. Exclusive breastfeeding is only breast milk for babies without any additional food or drink until the baby is 6 months old. Exclusive breastfeeding for infants up to age 6 months is influenced by various factors including knowledge, attitudes, educational, social cultural, economic of family and health workers. This study aims to determine knowledge, attitudes, educational, social cultural, economic of family and health workers that are associated with low exclusive breast feeding. The design of this study is descriptive analytical with cross sectional approach. Samples have been taken with total sampling technique as many as 111 mothers with babies aged 6-12 months. The results of this study shows that 12% of mothers breastfeed exclusively and 88% are not exclusive. 64% of mothers has a good knowledge of exclusive breastfeeding, 54% of mothers do not support the practice of exclusive breastfeeding, 53% of mothers are in the category of basic education, 58% of social and cultural mothers do not support the practice of exclusive breastfeeding, 65% mother is in the middle of family economic level and 60% of mothers received support from health workers to practice exclusive breastfeeding. Conclusion:Factors that are associated with low exclusive breast feeding in Cot Glie District namely knowledge (p=0,004), attitudes (p=0,000), educational (p=0,000), social cultural (p=0,000) and health workers (p=0,012). While the economic of family (p=0,074) do not have a relationship with the low exclusive breastfeeding in the region.(JKS 2013; 1:23-32 ) Key words : Exclusive breastfeeding, infant, factors

PENGARUH PEMBERIAN AIR SUSU IBU (ASI) EKSKLUSIF TERHADAP TIMBULNYA GEJALA AWAL ALERGI (Allergic March) PADA BAYI ATOPIK USIA 0-6 BULAN Mulya Safri
Jurnal Kedokteran Syiah Kuala Vol 12, No 3 (2012): Volume 12 Nomor 3 Desember 2012
Publisher : Universitas Syiah Kuala

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Abstrak. Penyakit atopik merupakan penyakit yang umum terjadi pada anak-anak dan merupakan masalah kesehatan serius di dunia. Dermatitis atopik, asma, alergi makanan dan rinitis alergi pada bayi merupakan perjalanan alamiah penyakit alergi yang dikenal dengan istilah “allergic march”. Studi menunjukkan bahwa pemberian ASI eksklusif secara signifikan mengurangi risiko alergi pada bayi atopik. Penelitian ini bertujuan untuk melihat pengaruh pemberian ASI eksklusif terhadap timbulnya gejala awal alergi (allergic march) pada bayi atopik usia 0-6 bulan. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross sectional. Sampel diambil dengan teknik total sampling sebanyak 79 bayi berusia kurang dari 3 tahun. Hasil penelitian ini memperlihatkan dermatitis atopik dan mengi lebih banyak terjadi pada bayi laki-laki (59,5%). Dermatitis atopik merupakan gejala awal yang paling banyak timbul pada bayi atopik yaitu 54,5%. Sedangkan bayi yang mengalami dermatitis atopik dan mengi pada waktu yang bersamaan sebesar 26,6%. Sebagian besar bayi atopik (68,4%) tidak mendapatkan ASI eksklusif. Bayi atopik yang mendapat ASI non eksklusif lebih banyak yang menderita dermatitis atopik dan mengi dibandingkan dengan bayi yang mendapat ASI eksklusif [31 (39,3%) vs 12 (15,1%)] dan [11 (13,9%) vs 4 (5,1%)]. Gejala awal alergi berupa dermatitis atopik dan mengi lebih banyak terjadi pada bayi laki-laki dibandingkan bayi perempuan. Gejala awal yang paling banyak timbul adalah dermatitis atopik. Bayi yang mendapat ASI non eksklusif cenderung lebih rentan terhadap munculnya gejala awal alergi berupa dermatitis atopik, mengi maupun kombinasi dari keduanya. Abstract. Atopic disease is a common disease in children and is a serious health problem in the world. Atopic dermatitis, asthma, food allergies and allergic rhinitis in infants is a natural way of allergic disease known as "allergic march". Studies have shown that exclusive breastfeeding significantly reduces the risk of allergy in atopic infants. This study aimed to observe the effect of exclusive breastfeeding on the incidence of early symptoms of allergy (allergic march) in atopic infants aged 0-6 months. This study was a descriptive cross-sectional approach. Samples were taken with a total sampling technique as much as 79 infants aged less than 3 years. The results of this study showed atopic dermatitis and wheezing is more common in boys (59.5%). Atopic dermatitis is the most initial symptoms occur in atopic infants is 54.5%. While infants with atopic dermatitis and wheezing at the same time of 26.6%. Most atopic infants (68.4%) were not exclusively breastfed. Atopic infants who are breastfed more non exclusive with atopic dermatitis and wheeze compared with infants who were exclusively breastfed [31 (39.3%) vs 12 (15.1%)] and [11 (13.9%) vs 4 (5.1%)]. The early symptoms of allergy such as wheezing and atopic dermatitis is more common in boys than girls. Initial symptoms arise is the most atopic dermatitis. Babies who are breastfed exclusively non tend more susceptible to the emergence of the early symptoms of allergies such as atopic dermatitis, wheezing or a combination of both.

Standar emas pemeriksaan alergi makanan pada anak Mulya Safri
Jurnal Kedokteran Syiah Kuala Vol 8, No 3 (2008): Volume 8 Nomor 3 Desember 2008
Publisher : Universitas Syiah Kuala

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Abstrak, Alergi rnerupakan reaksi kekebalan abnormal yang dapat merugikan tubuh dan sering dijumpai pada anak dengan riwayat atopi. Kadar imunoglobulin E pada penderita ini biasanya tinggi sehingga dapat mengeluarkan · mediator seperti histamin dan lain-lain yang dapat menimbulkan gejala alergi. Diperlukan stander pemeriksaan yang tepat meliputi anamnesa, pemeriksaan fisik dan pemeriksaan penunjang untuk mendiagnosa penyskit alergi pada anak. Hasil perneriksaan penunjang tersebut dapat dijadikan pedornan untuk dilakukan pencegahan (avoidance) yang tepat terhadap makanan dan lingkungan, yang rnerupakan tindakan mutlak dan harus dilakukan pada seorang anak menderita alergi. Pencegahan terhadap alergen/makanan yang dilakukan sedini mungkin dapat menghindarkan seorang anak menderita alergi walaupun mempunyai bakat alergi. (JKS2008; 3: 151-156) Kata kunci : stander pemeriksaan; alergi; anak Abstrack. Allergy is the abnormal immunity reaction that can be found in the children who got the atopic history. The high titer of immunoglobulin E (IgE) found in this patient and the mediator like histamine and oilier kind of mediators that can induce the allergy reaction are secreted. The correct standard of examination is needed to diagnose allergy in children including anarnnesis, physical examination and supportive examination. So that, we can make some dismissed avoidance to related foods and environment which included in absolute steps to the children with allergy. The earlier avoidance to related foods can prevent allergy in the children even though to the risked one. (JKS 2008; 3: 151-156) Key word: standartexamination, alergy, child

HUBUNGAN PEMBERIAN SUSU SAPI DENGAN KEJADIAN MENGI PADA ANAK DI PENDIDIKAN ANAK USIA DINI (PAUD) ISLAM TERPADU AL-AZHAR Mulya Safri; Kulsum Kulsum; Sulaiman Yusuf; Novita Andayani; Jufitriany Ismy; Mala Hayati
Jurnal Kedokteran Syiah Kuala Vol 18, No 1 (2018): Volume 18 Nomor 1 April 2018
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v18i1.11211

Abstrak: Mengi adalah gejala asma yang paling umum pada anak.Salah satu faktor yang mempengaruhi terjadinya mengi adalah pemberian susu sapi pada anak.Studi ini bertujuan untuk mengetahui hubungan pemberian susu sapi dengan kejadian mengi pada anak di PAUD Islam Terpadu AL-AZHAR. Jenis studi ini adalah analitik observasional dengan desain cross-sectional. Responden studi ini adalah 60 orang tua dari anak dengan rentang usia 6 bulan – 5 tahun. Hasil studi didapatkan dengan menggunakan kuisioner yang telah valid dan reliabel yaitu kuisioner ISAAC dan kuisioner pemberian susu sapi. Hasil analisis data dengan menggunakan uji Chi Square didapatkan p value 0,045 (α0,05) sehingga terdapat adanya hubungan pemberian susu sapi dengan kejadian mengi pada anak. Kesimpulan dari studi ini adalah anak yang diberi susu sapi dapat meningkatkan risiko mengi dibandingkan anak yang tidak diberi susu sapi.Kata kunci: susu sapi, mengi, anak 6 bulan-5 tahun.Abstract:Wheezingis the main symptom of asthma in children. One of the factors predisposing this symptom is cow's milk consumption.The objective of this study is to identify the association between cow's milk consumption and wheezing incidence in children at PAUD Islam Terpadu AL-AZHAR.This is an analytic observational study with cross-sectional design. The sample of this study include 60 parents of children aged from 6 months to 5 years old. The result is obtained using valid and reliable questionnaires, ISAAC and cow's milk consumption questionnaire. Analyzed using Chi Square test, the result revealed p value of 0.045 (α0,05), indicating an association between cow's milk consumption and wheezing incidence in children. The conclusion of this study is that children consuming cow's milk have higher risk for experiencing wheezing.Keywords: cow's milk, wheezing, 6-month to 5-year-old children

HUBUNGAN FAKTOR PENGETAHUAN, SIKAP, PENDIDIKAN, SOSIAL BUDAYA, EKONOMI KELUARGA SERTA PERAN PETUGAS KESEHATAN TERHADAP RENDAHNYA PEMBERIAN ASI EKSKLUSIF Mulya Safri; Aulia Rahman Putra
Jurnal Kedokteran Syiah Kuala Vol 13, No 1 (2013): Volume 13 Nomor 1 April 2013
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v13i1.3431

Abstrak. Air Susu Ibu (ASI) eksklusif adalah pemberian ASI saja kepada bayi tanpa makanan atau minuman tambahan sampai bayi berusia 6 bulan. Pemberian ASI eksklusif pada bayi hingga usia 6 bulan dipengaruhi oleh berbagai faktor antara lain pengetahuan, sikap, pendidikan, sosial budaya, ekonomi keluarga dan petugas kesehatan. Penelitian ini bertujuan untuk mengetahui hubungan faktor pengetahuan, sikap, pendidikan, sosial budaya, ekonomi keluarga serta peran petugas kesehatan terhadap rendahnya pemberian ASI eksklusif. Penelitian merupakan penelitian deskriptif analitik dengan pendekatan cross sectional. Sampel diambil dengan teknik total sampling sebanyak 111 orang ibu-ibu yang memiliki bayi usia 6-12 bulan. Penelitian ini memperlihatkan 12% ibu menyusui secara eksklusif dan 88% yang tidak menyusui secara eksklusif. 64% ibu memiliki pengetahuan yang baik mengenai ASI eksklusif, 54% sikap ibu tidak mendukung praktek pemberian ASI eksklusif, 53% ibu berada pada kategori pendidikan dasar, 58% sosial budaya ibu tidak mendukung praktek pemberian ASI eksklusif, 65% ibu berada pada tingkat ekonomi keluarga menengah dan 60% ibu mendapat dukungan dari petugas kesehatan mengenai pemberian ASI eksklusif. Faktor-faktor yang berhubungan dengan rendahnya pemberian ASI eksklusif di Kecamatan Cot Glie Aceh Besar yaitu faktor pengetahuan (p=0,004), sikap (p=0,000), pendidikan (p=0,000), sosial budaya (p=0,000) dan petugas kesehatan (p=0,012). Sedangkan faktor ekonomi keluarga (p=0,074) tidak memiliki hubungan dengan rendahnya pemberian ASI eksklusif di wilayah tersebut. Abstract. Exclusive breastfeeding is only breast milk for babies without any additional food or drink until the baby is 6 months old. Exclusive breastfeeding for infants up to age 6 months is influenced by various factors including knowledge, attitudes, educational, social cultural, economic of family and health workers. This study aims to determine knowledge, attitudes, educational, social cultural, economic of family and health workers that are associated with low exclusive breast feeding. The design of this study is descriptive analytical with cross sectional approach. Samples have been taken with total sampling technique as many as 111 mothers with babies aged 6-12 months. The results of this study shows that 12% of mothers breastfeed exclusively and 88% are not exclusive. 64% of mothers has a good knowledge of exclusive breastfeeding, 54% of mothers do not support the practice of exclusive breastfeeding, 53% of mothers are in the category of basic education, 58% of social and cultural mothers do not support the practice of exclusive breastfeeding, 65% mother is in the middle of family economic level and 60% of mothers received support from health workers to practice exclusive breastfeeding. Conclusion:Factors that are associated with low exclusive breast feeding in Cot Glie District namely knowledge (p=0,004), attitudes (p=0,000), educational (p=0,000), social cultural (p=0,000) and health workers (p=0,012). While the economic of family (p=0,074) do not have a relationship with the low exclusive breastfeeding in the region.

Hubungan Karakteristik Klinis dan Laboratoris Terhadap Kejadian Miokarditis Difteri pada Anak di RSUD Dr. Zainoel Abidin Banda Aceh Tita Menawati Liansyah; Mulya Safri; Sulaiman Yusuf
Sari Pediatri Vol 22, No 3 (2020)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp22.3.2020.131-8

Latar belakang. Difteri merupakan penyakit infeksi yang disebabkan oleh Corynebacterium diphtheriae. Komplikasi terberat penyakit ini yaitu terjadinya miokarditis yang dapat mengakibatkan kematian.Tujuan. Mengetahui hubungan antara karakteristik klinis dan laboratoris terhadap kejadian miokarditis difteri pada anak di RSUDZA Banda Aceh.Metode. Jenis penelitian ini adalah observasional analitik dengan pendekatan cross sectional yang menggunakan data rekam medik pasien difteri periode Januari 2017 hingga Desember 2019. Sampel 101 pasien difteri dengan metode purposive sampling. Analisis data menggunakan univariat dan bivariat dengan Chi-square test. Hasil. Berdasarkan hasil analisis bivariat antara karakteristik klinis dengan terjadinya miokarditis difteri didapatkan hasil (CI=95%; p<0,05) untuk stridor dan (CI=95%; p>0,05) untuk variabel letak membran, demam, nyeri tenggorokan, suara parau, bull neck dan derajat difteri. Analisis antara karakteristik laboratoris (leukosit, Troponin I, CK-MB, SGOT dan SGPT) dengan terjadinya miokarditis difteri didapatkan hasil (CI = 95%; p >0,05)Kesimpulan. Terdapat hubungan antara variabel karakteristik klinis, yaitu stridor dengan terjadinya miokarditis difteri. Sementara variabel lain, seperti letak membran, demam, nyeri tenggorokan, suara parau, bull neck dan derajat difteri tidak ada hubungan dengan terjadinya miokarditis difteri. Tidak ada hubungan antara variabel karakteristik laboratoris (leukosit, Troponin I, CK-MB, SGOT dan SGPT) dengan terjadinya miokarditis difteri pada anak di RSUDZA Banda Aceh.

Early allergy symptoms in infants aged 0-6 months on breast milk substitutes Mulya Safri; Aulia Rahman Putra
Paediatrica Indonesiana Vol 55 No 1 (2015): January 2015
Publisher : Indonesian Pediatric Society

Background Atopic diseases are common in children and a serious health problem worldwide. Atopic dermatitis, food allergies, asthma and allergic rhinitis, have been described as the natural progression of allergic diseases, also known as the â€œallergic marchâ€. Cowâ€™s milk protein is known to be a common trigger of food allergies and hypersensitivity reactions during infancy. Objective To give an overview of the breast milk substitutes (BMS) and incidence of early allergy onset (allergic march) in atopic infants aged 0-6 months. Methods This cross-sectional study included a total of 40 atopic infants collected by consecutive sampling. A questionnaire was used for interview that inquired information on the type of BMS used, initial allergy complaints, the age of the emergence of early allergic symptoms, and the breakdown for BMS type. Univariate analysis was carried out to describe their characteristics as frequency distributions and percentages of each variables. Results Atopic dermatitis and wheezing were more common in boys (62.5%). Atopic dermatitis was the most common initial symptom to occur in atopic infants (52.5%). Atopic dermatitis and wheezing occurred together in 27.5% subjects. Early allergy symptoms that first occurred at the age of 1 month were seen in 42.9% for atopic dermatitis category, 37.5% for wheezing category, and 63.6% for both symptoms category, respectively. Cowâ€™s milk was the most common type of BMS given to atopic infants in the first 6 months of life (47.5%). Conclusion Early symptoms of allergies, such as atopic dermatitis and wheezing, are more common in boys than girls. Atopic dermatitis is the most common early symptom to arise, but both symptoms occur at an early age, often during the first month of life.Â

Nutritional status of infants with cow's milk allergy who consume breast milk vs. hypoallergenic formula Mulya Safri; Aulia Rahman Putra; Vidya Chatmayani Mulya
Paediatrica Indonesiana Vol 56 No 5 (2016): September 2016
Publisher : Indonesian Pediatric Society

Background Infants with CMA are prone to suffer malnutrition because of the inability to absorb nutrients due to bowel inflammation. Breast milk and hypoallergenic formula is the best nutritional intake in CMA infants.Objective To compare the nutritional status of CMA infants who were consumed breast milk and hypoallergenic milk.Methods We conducted a cross-sectional study included a total of 63 CMA infants aged 3-6 months collected by consecutive sampling. Infantâ€™s nutritional status measured by anthropometric exam were divided into well-nourished (-2 to 2 SD) or malnourished (<-2 or >2 SD). Type of milk consumption were asked directly to parents/caregivers through interviews.Results Most of our subject are well-nourished (75%). The number of CMA infants who were consumed breast milk or hypoallergenik milk is not a lot of difference, 51% vs 49%, respectively. There is no significant difference between the nutritional status of CMA infants who consumed breast milk and hypoallergenic milk (P=0.61).Conclusion because there were no differences between the nutritional status of CMA infants who consumed breast milk and hypoallergenic milk. Therefore it is recommended giving breast milk or hypoallergenic milk for the first 6 months of life to reduce cowâ€™s milk protein exposure.

Assessing the Difference in Time to Increase Hemoglobin Levels at 1 hour, 6 hours, and 12 hours after Blood Transfusion in Thalassemia Patients at the Regional General Hospital Dr. Zainoel Abidin Banda Aceh Riny Fasli; Heru Noviat Herdata; Dora Darussalam; Bakhtiar Bakhtiar; Sulaiman Yusuf; Syafruddin Haris; Rusdi Andid; Mulya Safri; Eka Destianti Edward
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 2 (2021): Budapest International Research in Exact Sciences, April
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i2.1809

Thalassemia is a congenital blood disorder characterized by reduced production of one or more globin chains. Thalassemia patients lack healthy hemoglobin which the body needs to be properly oxygenated. Blood transfusion is the main treatment for thalassemia patients. Checking hemoglobin levels after transfusion is a common test, but until now there is no definite uniformity of time to carry out these tests, so it will be detrimental to the patient and increase the length of the patient in the hospital. Assessing the difference in time to increase in hemoglobin levels at 1 hour, 6 hours, and 12 hours after blood transfusion in thalassemia patients. This research is an observational analytic study with cross sectional design. This study was conducted by examining the hemoglobin levels of thalassemia patients after 1 hour, 6 hours, and 12 hours after transfusion in thalassemia patients aged 1-18 years with a total sample of 40 people. The statistical analysis used was paired t test. The results showed that 20 men and 20 women and Most were in the age group 10-13 (35%), with an average Hb level at admission of 7.38 g / dL (95% CI). At 1 hour post-transfusion, the patient's mean Hb level increased by 8.97 g / dL (8,59-9,35 g / dL), at 6 hours post transfusion, 8.95 g / dL (8,57-9,32 g / dL), at 12 hours post transfusion increased by 9.60 g / dL (9,17-10,03 g / dL). Significant increase in Hb levels occurred at 1 hour and 12 hours after blood transfusion.

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