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All Journal Budapest International Research in Exact Sciences (BirEx Journal)
Dora Darussalam
Departement of Child Health, Faculty of Medicine, Univesitas Syiah Kuala/Zainal Abidin General Hospital, Banda Aceh, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Physics Transportation

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Initial Screening of Thyroid Function Test in Premature and Term Infants at General Hospital Dr. Zainoel Abidin Banda Aceh Pretyca Yudra Perdana; Dora Darussalam; Rusdi Andid; Mulya Safri; Syafruddin Haris; Nora Sovira
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2646

Abstract

Congenital hypothyroidism (CH) is the most common cause of mental retardation which can be prevented by early diagnosis and treatment. Premature infants have a higher risk of developing HK than term infants. Screening for CH in every newborn is important, however, in premature babies screening for CH using the TSH examination is often found to have normal levels in the first week of examination. This study is a cross sectional study where the research sample amounted to 62 infants who were divided into 2 groups, namely premature babies (n = 31) and term infants (n = 31). Statistical analysis used is Independent sample t test and Mann-Whitney U test. This study aims to assess the comparison of thyroid function (FT4 and TSHs) between premature infants and term infants at the first examination in the age range of 2 -6 days. The results showed that 90% (28/31) premature infants had hypothyroxinemia with lower FT4 levels than term infants (18.70 ± 6.50, 95% CI). TSHs levels in premature infants were higher than term infants (5.70 ± 5.27, 95% CI). This study concluded that FT4 is better at detecting thyroid function disorders in premature infants while TSHs are better at detecting abnormal thyroid function in term infants.
Quality of Life of Epileptic Children Using Pediatric “Quality of Life Inventory” TM (PedsQLTM) Assessment at RSUD Dr. Zainoel Abidin Banda Aceh Hirsa Agriani; Anidar Anidar; Eka Yunita Amna; Bakhtiar Bakhtiar; Sulaiman Yusuf; Dora Darussalam; Syafruddin Haris
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 4 (2021): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i4.2638

Abstract

Epilepsy is a chronic disease that causes social function barriers that affect quality of life. Clinical factors, demographics, psychosocial, and anti-epileptic drugs are reported to affect the quality of life of people with epilepsy. This study aims to assess the quality of life of children with epilepsy who seek treatment at the IKA section of RSUDZA. This research is an observational analytic study with a cross-sectional design at the neurology polyclinic and inpatient Dr. RSUD. Zainal Abidin Banda Aceh for the period April-May 2021. The research subjects are 2-18 years old. Quality of life assessment using generic PedsQLTM 4.0. Multivariate analysis was tested using logistic regression test. It was found that 60 epilepsy patients participated in the study and obtained a quality-of-life disorder based on parent reports of 28.3%, and children's reports of 34.1%. There was no statistically significant relationship between demographic factors and children's quality of life based on parental reports (p< 0.05). In the children's report, it was found that demographic factors in the form of unexpected parenting were risk factors for impaired quality of life (p <0.05). Abnormal EEG picture is a clinically significant factor for impaired quality of life in children with epilepsy (p<0.05). This study concludes that patients with risk factors namely unexpected parenting, abnormal EEG affect quality of life.
Co-Authors Anidar Anidar Bakhtiar Bakhtiar Eka Yunita Amna Hirsa Agriani Mulya Safri Nora Sovira Pretyca Yudra Perdana Rusdi Andid Sulaiman Yusuf Syafruddin Haris