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All Journal Jurnal Kedokteran Syiah Kuala Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Jurnal Ilmiah Mahasiswa Kedokteran Medisia
Nur Wahyuniati
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PERAN INTERFERON GAMMA PADA INFEKSI MYCOBACTERIUM TUBERCULOSIS Nur Wahyuniati; M.Imun M.Imun
Jurnal Kedokteran Syiah Kuala Vol 18, No 2 (2018): Volume 18 Nomor 2 Agustus 2018
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v18i2.18005

Abstract

Abstrak. Penyakit tuberkulosis masih tetap merupakan masalah kesehatan yang utama di dunia. Penyakit ini menyebabkan angka kesakitan yang tinggi pada jutaan penduduk dunia setiap tahunnya. Mycobacterium tuberkulosis (M.Tb) memiliki kemampuan aktifitas replikasi dan metabolisme yang tinggi dan memiliki kemampuan untuk bertahan hidup di dalam fagosit profesional. Respon imun seluler sangat berperan penting untuk proses eliminasi M. Tb. Sel TH1 yang teraktivasi akan mengeluarkan interferon gamma yang akan mengaktivasi makrofag. Interferon gamma memiliki peran yang sangat penting dalam imunitas protektif terhadap infeksi M.Tb.Kata kunci: Tuberkulosis, Mycobacterium tuberculosis, respon T­H1, Interferon gamma Abstract. Tuberculosis remains a major health problem in the world. This disease causes a high morbidity rate in millions of the world's population each year. Mycobacterium tuberculosis (M.Tb) has high replication and metabolism activity and has the ability to survive in professional phagocytes. Cellular immune responses play an important role in the elimination process of M. Tb. The activated TH1 cell will secrete interferon gamma that leads to activation of macrophages. Interferon gamma has a very important role in protective immunity against infection M.Tb.  Keywords: Tuberculosis, Mycobacterium tuberculosis, TH­1 response, Interferon gamma
Postpartum Coccydynia: an Anatomy Overview Reza Maulana; Nur Wahyuniati; Imai Indra
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 5, No 2 (2015): Life Sciences
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.401 KB)

Abstract

Coccydynia is a term that refers to a painful condition in and around the coccyx. This symptom is typically a discomfort or pain which is felt when sitting for long time and when rising from sitting position. Many physiologic and psychological factors contribute to its etiology, but the majority of cases were found to be aggravated by pregnancy and childbirth (postpartum). Luxation and fracture of the coccyx are the two most common lesion of postpartum coccydynia. This poster shows an anatomy overview especially the coccyx to increase the understanding about this symptom
Inflammation and the Migration of Mesenchymal Stem Cell Reza Maulana; Nur Wahyuniati; Imai Indra
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 5, No 2 (2015): Life Sciences
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.969 KB)

Abstract

Mesenchymal stem cells are adult non-hematopoietic stem cells with multilineage proliferation and differentiation capabilities. This type of stem cell has the multipotent ability to differentiate into osteocytes, tenocytes, adipocytes, chondrocytes and  bone marrow stromal cells. The migration mechanism of mesenchymal stem cell is not yet fully understood, but based on studies  that  have  been  done  recently  by  the  researchers  worldwide  shown  that  the inflammatory process plays an important role for mesenchymal stem cell migration. A number of chemokine that plays a role in the migration of mesenchymal stem cells such as MCP-1 (CCL2), CXCL8, RANTES (CCL5), LL-37, integrin β1, CD44 receptor, CCR2, CCR3, and tyrosine kinase receptors for the following growth factors: IGF -1, PDGF-bb, HGF and VEGF
Hubungan Dukungan Keluarga dengan Kualitas Hidup pada Pasien Penyakit Paru Obstruktif Kronik di Poli Paru BLUD RSUD. Zainoel Abidin Banda Aceh Dimas Maulana Agustian; Novita Andayani; Nur Wahyuniati
Jurnal Ilmiah Mahasiswa Kedokteran Medisia Vol 2, No 3: Agustus 2017
Publisher : Jurnal Ilmiah Mahasiswa Kedokteran Medisia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (336.091 KB)

Abstract

Penyakit Paru Obstruktif Kronik (PPOK) adalah penyakit paru yang memiliki keterbatasan jalan napas yang tidak sepenuhnya reversibel dan bersifat progresif yang disebabkan karena inflamasi kronik akibat pajanan partikel atau gas beracun dalam waktu yang lama. Penyakit Paru Obstruktif Kronik menyebabkan gangguan kualitas hidup. Salah satu faktor resiko yang mempengaruhi kualitas hidup pasien PPOK adalah dukungan keluarga. Tujuan dari penelitian ini untuk mengetahui hubungan dukungan keluarga dengan kualitas hidup pada pasien PPOK di Poli Paru BLUD RSUD. Zainoel Abidin Banda Aceh. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional dan telah dilakukan pada bulan Mei-Juli 2016 dengan jumlah responden 30 orang. Hasil analisis komparatif dengan uji Mann Whitney menunjukkan hubungan yang signifikan antara dukungan keluarga dengan kualitas hidup (p = 0,028) pada pasien PPOK di Poli Paru RSUD dr. Zainoel Abidin Banda Aceh. Penelitian ini diharapkan menjadi sumber informasi dan masukan bagi keluarga pasien untuk senantiasa memberikan dukungan serta motivasi kepaada pasien PPOK sebagai salah satu upaya untuk terus menjaga kualitas hidup pasien.Chronic Obstructive Pulmonary Disease (COPD) is a lung disease that has limited airway that is not fully reversible and progressive caused by chronic inflammation due to exposure of toxic gas particles over a long time. Chronic Obstructive Pulmonary Disease causes impaired quality of life. One of the risk factors that affect the quality of life of patients with COPD is family support. The Purpose of this study was to determine the relationship of family support and quality of life in COPD patients at Lung Polyclinics Zainoel Abidin Hospital, Banda Aceh. This research is an observational analytic research with crosss-sectional approach and has been done in the month of May to July 2016 with thirty respondents. The results of comparative analysis with Mann Whitney test showed a significant relationship between family support with the quality of life of patients with COPD at Lung Polyclinics Zainoel Abidin Hospital, Banda Aceh. This research expected to be a source of information and advice families of patients with COPD, and effort to maintain quality of life patients with COPD
Co-Authors Dimas Maulana Agustian Imai Indra M.Imun M.Imun Novita Andayani Reza Maulana