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Ayu Diandra Sari
Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital
Medicine & Pharmacology Public Health

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The Effect of Thiamine Supplementation for Critically Septic Patient: An Evidence-Based Case Report Ayu Diandra Sari; Melyarna Putri; Sheena R. Angelia; Mulianah Daya; Anak Agung Eka Widya Saraswati; Diyah Eka Andayani; Diana Sunardi
World Nutrition Journal Vol. 5 No. 1 (2021)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.i1.0003

Abstract

Sepsis has been accounted for various burdens worldwide, especially in critically ill patients. This could eventually lead to inflammatory response, provocation ischemia and lactic acidosis. On the other hand, thiamine was suggested as a coenzyme which could improve the outcome of those patients. Thus, we conducted an evidence-based case study with research on PubMed, ProQuest, and Scopus using a search strategy focusing on RCT or cohort study on thiamine supplementation/level towards the outcome of critically ill patients with sepsis. We found three articles eligible for review after full-text assessment. Articles were appraised using the University of Oxford’s tools for critical appraisal. It was known that all studies were good in terms of validity and applicability. This study showed that thiamine supplementation could improve lactate clearance and reduce mortality risk, moreover, thiamine deficiency could increase the risk of lactate acidosis. However, a high level of thiamine was associated with a high level of lactate in patients with liver failure. Therefore, thiamine supplementation could be recommended for critically ill patients with sepsis and normal liver function. Further research, such as RCT or systematic review on thiamine supplementation for age groups to make this study more applicable.
Medical nutrition therapy and vitamin D supplementation improved nutritional status and quality of life in relapse systemic lupus erythematosus patient : A case report Ayu Diandra Sari; Yohannessa Wulandari; Diyah Eka Andayani
World Nutrition Journal Vol. 5 No. S3 (2022): Selected conference proceedings of the Nutri Virtual Symposium 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.S3.0025

Abstract

Medical nutrition therapy (MNT) plays pivotal role in comprehensive management of autoimmune disease, includes systemic lupus erythematosus (SLE). Meanwhile, MNT for SLE is still not a concern in many international clinical practice guidelines. Many studies reported about nutritional declines and metabolic complications related to long term corticosteroid use in SLE patients, i.e. malnutrition, sarcopenia, hypovitaminosis D, hypertension and etc. Besides, obesity is more expected become important risk factor in SLE.
Co-Authors Anak Agung Eka Widya Saraswati Diana Sunardi Diyah Eka Andayani Diyah Eka Andayani Melyarna Putri Mulianah Daya Sheena R. Angelia Yohannessa Wulandari