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All Journal Nexus Kedokteran Komunitas World Nutrition Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH)
Ratih Puspita Febrinasari
Sebelas Maret University
Computer Science & IT Decision Sciences, Operations Research & Management Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health

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The Relationship between Knowledge about Antibiotics with Usage Frequency of Non-prescription Antibiotics on Non-Medical Student of Sebelas Maret University Nadya Kemala Amira; Arsita Eka Prasetyawati; Ratih Puspita Febrinasari
Nexus Kedokteran Komunitas Vol 5, No 1 (2016): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (480.888 KB)

Abstract

Background: Antibiotics are the drugs most widely used and abused in the world. The most frequent form of antibiotic misuse is self-medication by various groups of society including students. Lacking of knowledge of the students, especially non-medical students, about antibiotics plays an important role in the discovery of many cases of antibiotics misuse. This study aimed to investigate the relationship between knowledge about antibiotics with usage frequency of non-prescription antibiotics on non-medical student of Sebelas Maret University. Method: This study was an observational analytic study with cross sectional approach. Sample collected from 186 non-medical students from 5 faculties in Sebelas Maret University which were randomly drawn by cluster random sampling technique. Each respondent was given a questionnaire regarding knowledge about antibiotics and the usage frequency of non-prescription antibiotics that has been tested for validity and reliability by researcher. The research data were tested with the nonparametric Spearman correlation test (? = 0.05). Result: Spearman correlation test results a significant correlation between knowledge about antibiotics with usage frequency of non-prescription antibiotics on non-medical students of Sebelas Maret University with p < 0.05 (p = 0.000). The test results also showed a strong correlation between the two variables with a correlation coefficient (r) -0.681, with increased knowledge about antibiotics will decrease the usage frequency of non-prescription antibiotics on non-medical students of Sebelas Maret University. Conclusion: There was a strong relationship between knowledge about antibiotics with the usage frequency of non-prescription antibiotics on non-medical students of Sebelas Maret University. Better knowledge of antibiotics, would reduce the usage frequency of non-prescription antibiotics. Keywords: antibiotics, knowledge about antibiotics, the usage frequency of non-prescription antibiotics
Antioxidant Activity of Ethanol Extract of Secang Wood (Caesalpinia sappan L.), Gotu Kola (Centella asiatica L.), and Their Combinations with DPPH Assay Binti Maulina Putri; Sugiarto; Brian Wasita; Ratih Puspita Febrinasari
Proceeding of International Conference on Science, Health, And Technology 2021: Proceeding of the 2nd International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1062.209 KB) | DOI: 10.47701/icohetech.v1i1.1081

Abstract

Antioxidants are the properties of active compounds that can prevent the formation or binding of free radicals and other molecules and inhibit oxidation reactions. Secang wood (Caesalpinia sappan L.) and Gotu kola (Centella asiatica L.) are plants that contain lots of phytochemical compounds used as traditional drinks such as steeping drinks to date. Combining several natural ingredients is believed to provide more benefits and a more effective dosage if used properly. This study aims to determine the antioxidant activity of the ethanol extract of secang wood and gotu kola and their combinations (1:1, 2:1, 1:2) based on the IC50 value with various concentrations and replication 3 times for each sample from the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Ascorbic acid was also used as a positive control for this assay. Secang wood and gotu kola were extracted using maceration method with 96% ethanol as solvent. The results showed that the IC50 antioxidant activity of 34.173 ppm of secang wood ethanol extract was more active (very strong) compared to 160.236 ppm of gotu kola extract (weak). The best combination of ethanol extract mixture of secang wood and gotu kola which resulted in the strongest activity among the three combinations was a 1:1 ratio of 59.431 ppm (strong).
The relationship of vitamin A, C, and E intake with premature aging of facial skin in female market traders Chintya Wulandarie; Sumardiyono Sumardiyono; Ratih Puspita Febrinasari
World Nutrition Journal Vol. 7 No. 01 (2023): Volume 07 Issue 1, August 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/10.25220/WNJ.V07.i1.0007

Abstract

Background: Women's market traders are jobs that are often exposed to free radicals, including air pollution, cigarette smoke, sun exposure and have a high workload that causes stress. Antioxidants can protect the skin from free radicals and can inhibit the process of premature aging of facial skin which are found in vegetables and fruits such as vitamins A, C, E. Objective: To determine the relationship between intake of vitamins A, C, and E with premature aging of market traders in the form of wrinkles around the face. Methods: Observational research with cross sectional method. The sampling technique is multi-stage cluster sampling. This research was conducted at Beringharjo Market with a total sample of 172 respondents with inclusion criteria namely female traders, aged 26–45 years, workers in the market area. The exclusion criteria are tourists/market visitors, women who are pregnant and breastfeeding. The research variables for intake of vitamins A, C, and E used the SQ-FFQ (Semi-Quantitative Food Frequency Questionnaire) questionnaire with the interview method. In measuring the number of wrinkles on facial skin using photoaging through facial shooting using a Sony A7R3 camera with a 24-70 lens that is analyzed by a dermatologist (skin expert). Data analysis technique using multiple logistic regression analysis. This analysis uses SPSS software version 22.0. Results: In the multiple logistic regression test, p = 0.037 (p <0.05) means that there is a relationship between vitamin A intake and premature aging of facial skin. On vitamin C intake, p = 0.436 (p> 0.05), meaning that there is no relationship between vitamin C intake and premature aging of facial skin. And on vitamin E intake, p = 0.171 (p> 0.05) there is no relationship between vitamin E intake and premature aging of facial skin. Conclusion: Intake of vitamin A has a significant relationship with the occurrence of premature aging of the face, but vitamins C and E do not have a significant relationship with the occurrence of premature aging of the facial skin
Co-Authors Arsita Eka Prasetyawati Binti Maulina Putri Brian Wasita Chintya Wulandarie Nadya Kemala Amira Sugiarto Sumardiyono Sumardiyono